Re: [aroma.affymetrix] peculiar array quality

2010-07-23 Thread Henrik Bengtsson
Hi, it's hard to say what causing this, but if you see it in several samples at the same location, then my immediate thought is that you reference signal may carry it. Are you using the average of the pool of all samples as a reference or how do you calculate it? How many samples to you have

[aroma.affymetrix] peculiar array quality

2010-07-21 Thread Matt Wilkerson
Hello, I have detected what I think is an array quality issue and wanted to get others' opinions about this phenomena. I observed this issue on chromosome views of CN from SNP6 arrays. It looks like a smearing effect where CN has irregular values and a range of large negative numbers to zero