Hi,
it's hard to say what causing this, but if you see it in several
samples at the same location, then my immediate thought is that you
reference signal may carry it. Are you using the average of the pool
of all samples as a reference or how do you calculate it? How many
samples to you have
Hello,
I have detected what I think is an array quality issue and wanted to get
others' opinions about this phenomena.
I observed this issue on chromosome views of CN from SNP6 arrays. It looks
like a smearing effect where CN has irregular values and a range of large
negative numbers to zero