Re: [Bioc-devel] a pattern to be avoided? mcols(x)$y <- z

Hi Vince, This issue was reported here a couple of weeks ago: https://github.com/Bioconductor/GenomicRanges/issues/11 Internally $<- uses something like: do.call(DataFrame, list(DF1, DF2)) to combine the metadata columns. However in some situations the do.call(DataFrame, list(...)) form

[Bioc-devel] a pattern to be avoided? mcols(x)$y <- z

The following comes up in use of Fdb.InfiniumMethylation.hg19::getPlatform debug: mcols(GR)$channel <- Rle(as.factor(mcols(GR)$channel450)) Browse[3]> system.time(uu <- Rle(as.factor(mcols(GR)$channel450))) user system elapsed 0.020 0.003 0.022 Browse[3]>