Re: [Bioc-devel] 'semantically rich' subsetting of SummarizedExperiments

2014-10-11 Thread Vincent Carey
Is there anything on the order of as([GeneSet], GRanges) around? On Sat, Sep 20, 2014 at 11:34 PM, Gabe Becker becker.g...@gene.com wrote: Sean and Vincent, The goal of what we are doing builds off of what Martin has in GSEABase. We were looking to see how much benefit we can get with

Re: [Bioc-devel] 'semantically rich' subsetting of SummarizedExperiments

2014-10-11 Thread Martin Morgan
On 10/11/2014 08:41 AM, Vincent Carey wrote: Is there anything on the order of as([GeneSet], GRanges) around? no, I don't think so; obviously of use and following a common theme. Martin On Sat, Sep 20, 2014 at 11:34 PM, Gabe Becker becker.g...@gene.com wrote: Sean and Vincent, The goal

Re: [Bioc-devel] 'semantically rich' subsetting of SummarizedExperiments

2014-10-11 Thread Michael Lawrence
But what it would do exactly? Probably would want to be able to extract a gene list from a TxDb, then extract the desired type of structure from the TxDb. Not too bad right now, but it would be nice to leverage the identifier type information on the gene list object. Currently: tx -

Re: [Bioc-devel] 'semantically rich' subsetting of SummarizedExperiments

2014-10-11 Thread Vincent Carey
On Sat, Oct 11, 2014 at 5:17 PM, Michael Lawrence lawrence.mich...@gene.com wrote: But what it would do exactly? Probably would want to be able to extract a gene list from a TxDb, then extract the desired type of structure from the TxDb. Not too bad right now, but it would be nice to

Re: [Bioc-devel] 'semantically rich' subsetting of SummarizedExperiments

2014-09-22 Thread Cook, Malcolm
Hi, https://github.com/vjcitn/biocMultiAssay/blob/master/vignettes/SEresolver.Rnw shows some modifications to [ that allow subsetting of SE by gene or pathway name Without reading the code, do you intend that SE[i,j] will , if i is provided as vector of string, will subset those rows where

Re: [Bioc-devel] 'semantically rich' subsetting of SummarizedExperiments

2014-09-22 Thread Vincent Carey
On Mon, Sep 22, 2014 at 10:17 AM, Cook, Malcolm m...@stowers.org wrote: Hi, https://github.com/vjcitn/biocMultiAssay/blob/master/vignettes/SEresolver.Rnw shows some modifications to [ that allow subsetting of SE by gene or pathway name Without reading the code, do you intend that

Re: [Bioc-devel] 'semantically rich' subsetting of SummarizedExperiments

2014-09-21 Thread Vincent Carey
Sounds very nice. Anything for the impending release? On Sat, Sep 20, 2014 at 11:34 PM, Gabe Becker becker.g...@gene.com wrote: Sean and Vincent, The goal of what we are doing builds off of what Martin has in GSEABase. We were looking to see how much benefit we can get with something

Re: [Bioc-devel] 'semantically rich' subsetting of SummarizedExperiments

2014-09-20 Thread Sean Davis
Hi, Vince. I'm coming a little late to the party, but I agree with Kasper's sentiment that the less magical approach of using subsetByXXX might be the cleaner way to go for the time being. Sean On Sat, Sep 20, 2014 at 10:42 AM, Vincent Carey st...@channing.harvard.edu wrote:

Re: [Bioc-devel] 'semantically rich' subsetting of SummarizedExperiments

2014-09-20 Thread Tim Triche, Jr.
Agreed with Sean, having tried implementing to magical alternative --t On Sep 20, 2014, at 9:31 AM, Sean Davis sdav...@mail.nih.gov wrote: Hi, Vince. I'm coming a little late to the party, but I agree with Kasper's sentiment that the less magical approach of using subsetByXXX might be

Re: [Bioc-devel] 'semantically rich' subsetting of SummarizedExperiments

2014-09-20 Thread Vincent Carey
OK by me to leave [ alone. We could start with subsetByEntrez, subsetByKEGG, subsetBySymbol, subsetByGOTERM, subsetByGOID. Utilities to generate GRanges for queries in each of these vocabularies should, perhaps, be in the OrganismDb space? Once those are in place no additional infrastructure is

Re: [Bioc-devel] 'semantically rich' subsetting of SummarizedExperiments

2014-09-20 Thread Gabe Becker
Hey all, We are in the (very) early stages of experimenting with something that seems relevant here: classed identifiers. We are using them for database/mart queries, but the same concept could be useful for the cases you're describing I think. E.g. mysyms = GeneSymbol(c(BRAF, BRCA1)) mysyms

Re: [Bioc-devel] 'semantically rich' subsetting of SummarizedExperiments

2014-09-20 Thread Sean Davis
On Sat, Sep 20, 2014 at 3:11 PM, Gabe Becker becker.g...@gene.com wrote: Hey all, We are in the (very) early stages of experimenting with something that seems relevant here: classed identifiers. We are using them for database/mart queries, but the same concept could be useful for the cases

Re: [Bioc-devel] 'semantically rich' subsetting of SummarizedExperiments

2014-09-20 Thread Vincent Carey
On Sat, Sep 20, 2014 at 3:11 PM, Gabe Becker becker.g...@gene.com wrote: Hey all, We are in the (very) early stages of experimenting with something that seems relevant here: classed identifiers. We are using them for database/mart queries, but the same concept could be useful for the cases