[Bioc-devel] Bioconductor Devel 3.11 Notification

Thank you for your patience. We now have Bioconductor 3.11 running on all three platforms (linux, mac, windows) as seen on our daily build report. http://bioconductor.org/checkResults/3.11/bioc-LATEST/ We encourage all maintainers to monitor their packages as there have been many changes with

[Bioc-devel] From Biostring matching to short read mapping

Dear bioc-devel, multicrispr provides functions for Crispr/Cas9 gRNA design (and is being prepared for BioC). One task involves finding all genomic (mis)matches of a 23-bp candidate Cas9 sequence. Currently this is done with