The human genome is arranged in 46 chromosomes. The longest is ~250 Mb
(~2^28). While a Hilbert curve layout of a single chromosome tends to be
informative, there is no obvious meaning in treating the complete human
genome as a single 3 Gb linear sequence.
Wolfgang
On 10/03/2017 21:54,
Two replies:
1. Downsampling?
In case you want to use the Hilbert curve for visualisation, please note
that you will need a graphics device with resolution 65536 x 65536 to
display it. Many people have smaller screens, so binning the genome
(e.g. into bins of 10x10=100nt) could be a practical
On Thu, Mar 9, 2017 at 2:44 AM, Sohaib Ghani
wrote:
> I am trying to simulate hilbertcurve (of Bioconductor package) of level 16
> in R. It takes about 4^16=4 Billion points. I want to generate the hilbert
> curve of genome (size about 3 billion).
>
> But I am getting