[ccp4bb] Call for Stanford-SLAC CryoEM Center (S2C2) Applications

We would like to announce the full operation of two new Titan-Krios electron microscopes with high-throughput detectors (K3 and Falcon 4) dedicated to high resolution biological single particle data collection at the Stanford-SLAC CryoEM Center (S2C2) located in the new Arrillaga Science Center

[ccp4bb] Crystallographer position at Sosei Heptares

Dear all, We are currently seeking a talented crystallographer to join the Biomolecular Structure group at our research facility (Granta Park, Cambridge, UK), to work on GPCR structure determination to enable drug discovery efforts. The ideal candidate would hold a PhD in protein crystallography

[ccp4bb] XFEL Computational Crystallographer Research Scientist at Berkeley Lab

Dear XFEL and Structural Biology Colleagues, Please note that we have an open Research Scientist position in Berkeley Lab’s *Molecular Biophysics and Integrated Bioimaging Division .* The successful candidate, with a strong interest in

[ccp4bb] Research technician Position in Vienna

** *Research Technician Position in Djinovic Group* */Dept. of Structural and Computational Biology/* *Max Perutz Labs, University of Vienna* ** *Research technician position*is available in the *Djinovic-Carugo**laboratory*

Re: [ccp4bb] Advice on DNA negative staining

Hiya *Half an hour in the library saves a month of research.* That's what my late advisor Dr. Frolow used to say a lot and he was not wrong. Erenpreisa J. 1981. Staining of DNA with uranlyacetate in hydrolyzed ultrathin sections. Acta histochem 68(1): 22-26 there are several very clever

Re: [ccp4bb] Advice on DNA negative staining

Hi Meytal, 1. The concentration seems way too high at 254mg/ml. Typically 0.1-5mg/ml are used. 2. Uranyl ions react with phosphate groups resulting in positive stain. The resulting contrast is frequently poor. 3. Rotary shadowing can be used to enhance contrast. Best, Daniel On 4 Aug 2020,

[ccp4bb] Job advert for a structural biology/biophysics role in PROTAC drug discovery

Dear all, We have a particularly exciting job opportunity in our lab, the PROTAC drug discovery collaboration between the group of Prof Alessio Ciulli at the University of Dundee and Boehringer Ingelheim. Our group are world leaders in the field of PROTACs, which has rapidly become one of

Re: [ccp4bb] Two scientist / software developer positions on neutron diffraction at RAL

Dear all, Please be reminded about the two posts advertised below. You can ignore the closing date of 2nd August shown here - the first post has been adjusted to close on the 9th August as well, to be in line with the other position. Best wishes -- David On Thu, 23 Jul 2020 at 19:25, David

Re: [ccp4bb] Help needed (input files)

Fred, you could use the Academic version of Desmond freely available here: https://www.deshawresearch.com/resources_desmond.html The only difference from the commercial version is absence of OPLS3e force field but you still could use GPU. вт, 4 авг. 2020 г. в 10:08, Fred Vellieux : > Hello, > >

[ccp4bb] Help needed (input files)

Hello, I need to perform some MD calculations and then trajectories of some small molecules analyzed. What I have is 1. protein 2. cofactor (FAD) 3. small molecule (either single O2 atom or single Chlorine atom) 4. crystallographic waters The software I can access is either Gromacs (with yum