On 12/19/16 11:25, herman.schreu...@sanofi.com wrote:
Dear Andy,
I don’t think you will solve this pre-Xmas
...
There is hope of a pre-Christmas solution. Convert to Eastern Orthodox;
that will provide an extra two weeks margin, due to the Orthodox use of
the Julian calendar.
--
Dear Andy,
I don't think you will solve this pre-Xmas, but here are some more suggestions:
-is there any relationship with the unit cell of the parent, unmutated protein?
This might give some ideas of the packing of the problem crystals.
-are some promising solutions being rejected due to
Dear Andrew,
Just a few questions:
-Do the processing/refinement programs suggest twinning?
-Are you sure your space group is P21 and not P2? Did you try MR in P2?
-How many protein molecules do you expect in the asymmetric unit?
P2(1) is a very low symmetry space group. In this case I would not
