Dear Brad,
the flexibility, that is how far a protein is stabilized with cold and heat
denaturation of a protein,
this inturn depends on
1.solvation enthalpy of nonpolar moieties(need more energy,so there needs to
be some randomness)
2.shift in temparature due to the enthalpy associated with tra
On Tuesday 13 November 2007 06:41, Brad Bennett wrote:
>
> I would be interested then to know how the community feels about the
> correlation of B-factors to protein flexibility. It is generally accepted
> that these are linked but are there any new papers that address this?
This is the basis of
Hello all:
There are studies, some much older and some relatively new, by Kossiakoff,
Karplus and others showing that B-factors of amide nitrogen atoms are not
correlated to their hydrogen/deuterium exchange behavior. Along similar
lines, I would be interested then to know how the community feels