Re: [ccp4bb] How to make an unnatural amino acid ligand?

2013-01-09 Thread Debreczeni, Judit
our Code of Conduct and Policies. -Original Message- > From: CCP4 bulletin board [mailto:CCP4BB@JISCMAIL.AC.UK] On Behalf Of > Ian Clifton > Sent: 09 January 2013 12:44 > To: CCP4BB@JISCMAIL.AC.UK > Subject: [ccp4bb] How to make an unnatural amino acid ligand? > > I need

[ccp4bb] How to make an unnatural amino acid ligand?

2013-01-09 Thread Ian Clifton
I need to make dictionaries for a ligand that includes an unnatural amino acid (D chirality, and unnatural side‐chain) amongst a short sequence of natural amino acids. Sounds easy, but how to do it? I’m thinking of first making my unnatural amino acid in isolation, then using an editor to fix up th