Dear CCP4BB
With this week's update of the PDB, over one thousand (1018 to be exact!) SARS-CoV-2-related structures are now freely available in the PDB. The first SARS-CoV-2 structure, a high-resolution crystal structure of the coronavirus main protease (PDB <http://www.wwpdb.org/pdb?id=pdb_00006lu7> 6lu7), was released early in the pandemic on February 5, 2020. Since then, structural biologists have determined the structures of most of the proteins in the SARS-CoV-2 proteome, including the spike protein binding to its ACE2 receptor and neutralizing antibodies, and the main protease, the papain-like proteinase, and other promising drug discovery targets. All of the structures and related data are available for exploration from dedicated pages on wwPDB partner websites: <http://rcsb.org/covid19> RCSB PDB, <https://www.ebi.ac.uk/pdbe/covid-19> PDBe, <https://pdbj.org/featured/covid-19?tab=all> PDBj, and <https://bmrb.io/coronavirus.shtml> BMRB. Rapid public release of SARS-CoV-2 structures has greatly increased our understanding of Covid-19, allowed direct visualization of emerging variants of the virus, and facilitated structure-guided drug discovery and reuse to combat infection. Open access to PDB structures has already enabled design of effective vaccines against SARS-CoV-2. The response of the research community to the pandemic has highlighted the importance of open access to scientific data in real time. The wwPDB strives to ensure that 3D biological structure data remain freely accessible for all, while maintaining as comprehensive and accurate an archive as possible. The impact of these over one thousand structures, and many more coronavirus protein structures to come, stands as a testament to the importance of open access to structural biology research data. Regards John PDB -- John Berrisford PDBe European Bioinformatics Institute (EMBL-EBI) European Molecular Biology Laboratory Wellcome Trust Genome Campus Hinxton Cambridge CB10 1SD UK Tel: +44 1223 492529 <http://www.pdbe.org/> http://www.pdbe.org <http://www.facebook.com/proteindatabank> http://www.facebook.com/proteindatabank <http://twitter.com/PDBeurope> http://twitter.com/PDBeurope ######################################################################## To unsubscribe from the CCP4BB list, click the following link: https://www.jiscmail.ac.uk/cgi-bin/WA-JISC.exe?SUBED1=CCP4BB&A=1 This message was issued to members of www.jiscmail.ac.uk/CCP4BB, a mailing list hosted by www.jiscmail.ac.uk, terms & conditions are available at https://www.jiscmail.ac.uk/policyandsecurity/
