Yes, Eleanor D. is right. I had a similar experience. MR did not provide me
the solution with monomeric protein. However, when i used dimer as a search
model, it appeared to be a low-hanging fruit afterwards. May be you have a
similar situation, there are very less possibilities to explain
With such a lot of molecules, I would check for oligamers. Look at the
MOLREP self rotation - is there anything obvious? Send the*.ps if you like
and I can comment.
And do the models form oligimers? If so search with that..
Eleanor
And as Randy says - try PHASER ..
On 31 October 2016 at
Dear Alex,
We’ve had very good luck using Phaser to place large numbers of copies of good
models. It’s in this kind of case where the increased sensitivity of the
likelihood approach really helps. I would suggest trying the different choices
of model as alternatives, and you might also want
