Dear All, Two research positions funded by the VolkswagenStiftung are available in the group of Prof. Utz Fischer at the Theodor-Boveri Institute of the Julius-Maximilians-Universität Würzburg.
The successful candidates will participate in a structure-based drug design approach to combat the zoonotic risk imposed by poxviral reservoirs and human pathogenic poxvirus strains. To this end, we target the unique poxviral transcription machinery, which relies exclusively on virus-encoded proteins. As a basis, we recently reported the isolation and comprehensive structural investigation of this machinery in different phases of action. This now enables the identification and design of small molecules that interfere with poxviral gene expression and their subsequent translation into antiviral pharmaceuticals. Last but not least, the unexpected severity of the ongoing monkeypox outbreak underlines the timeliness of this project. See our recent publications on the topic: Grimm et al., Cell 179 (7): 1537-1550 (2019) Hillen et al., Cell 179 (7): 1525-1536 (2019) Grimm et al., Nat. Struct. Mol. Biol. 28 (10), 779-788 (2021) Grimm et al., TIBS (2022) or for a quick overview our website: https://www.biozentrum.uni-wuerzburg.de/biochem/research-groups/grimm-group-structural-biology/projects/ We offer: A stimulating international research environment in a well-equipped and modern department at the Biocenter of the University, which provides diverse opportunities for collaborations. The GSLS provides the framework for a structured PhD education program. Remuneration will be according to public service positions in Germany, 100% TV-L E13 (Postdoc) or 65% TV-L E13 (PhD student). Disabled applicants will be preferentially considered in case of equivalent qualifications. Requirements: The candidates should possess a solid background in biochemistry or virology. The Postdoc position requires a PhD in the life sciences. The PhD Student position requires an M.Sc. in the life sciences or equivalent for enrolment at the Würzburg Graduate School of Life Sciences (GSLS). Experience in protein bioinformatics, biophysics or structural biology is beneficial. Application/ Contact: Please send your application, which should include a statement of motivation, a detailed CV and the contact details of two referees as a single file by e-mail to the Department of Biochemistry. For further information, please contact Utz Fischer utz.fisc...@uni-wuerzburg.de Tel.: +49 931-3184029 or Clemens Grimm clemens.gr...@uni-wuerzburg.de Tel.: +49 931-3184031 ######################################################################## To unsubscribe from the CCP4BB list, click the following link: https://www.jiscmail.ac.uk/cgi-bin/WA-JISC.exe?SUBED1=CCP4BB&A=1 This message was issued to members of www.jiscmail.ac.uk/CCP4BB, a mailing list hosted by www.jiscmail.ac.uk, terms & conditions are available at https://www.jiscmail.ac.uk/policyandsecurity/
