Hi,
If your Hg dataset is not isomorphous with the SeMet you can cut out some
density and use cross-crystal averaging (molecular replacement using electron
density) to transfer the Hg phases to the Se dataset. You can then try using
an anomalous difference fourier map to find more or weaker Se
Dear William,
In a similar circumstance, we cut out the density from one crystal, and used
that to solve the structures of non-isomorphous crystals by molecular
replacement. At this point, we had an envelope (needed to cut out the
density), initial maps, and operators to place one copy of the
Dear all,
I am trying to phase a largish novel structure of 130 kDa with P21 (sometimes
P222) space group. So far I have collected a few 3.5ish-Å 3-wavelength MAD
datasets from SeMet derivatives as well as an anisomorphous 6Å Hg peak dataset
(with detectable anomalous signal). As my crystal is
