Re: [ccp4bb] antibody crystallization

2008-01-22 Thread William Scott
I want to thank the very many people who responded to my inquiry. I'm overwhelmed and really appreciative. I've still got to read through it all, but a clear (near-unanimous) consensus is emerging. All the best, and again thanks very much for the help. I really appreciate it. Bill

[ccp4bb] antibody crystallization

2008-01-20 Thread William Scott
Hi folks: A colleague has an antibody they would like a crystal structure of, bound to a peptide. Currently it is a whole antibody. From my superficial search of the literature, it looks like everyone uses Fab fragments in such cases. Is this true, and is it stupid to try the whole