Re: [ccp4bb] Rosetta vs Modeller

2009-12-16 Thread Eric Bennett
Subhendu wrote: Hi everyone, I am currently in the process of solving some antigen-antibody complex structures. I was wondering if people here have used Modeller and Rosetta for homology modeling and have any recommendations.I would like to build the model of the antigen/antibody to the

Re: [ccp4bb] Rosetta vs Modeller

2009-12-16 Thread subhendu chakraborti
Thank you, guys. Subhendu On Wed, Dec 16, 2009 at 5:21 AM, Eric Bennett er...@pobox.com wrote: Subhendu wrote: Hi everyone, I am currently in the process of solving some antigen-antibody complex structures. I was wondering if people here have used Modeller and Rosetta for homology

Re: [ccp4bb] Rosetta vs Modeller

2009-12-15 Thread Akram Alian
Subhendu I wonder if you approached this issue by molecular replacement using the antigen-binding fragment (Fab) of any antibody (e.g. 1FVD). You can separate the Fab into the two domains; Variable and Constant, delete the loops from each, and use them as models in Molecular replacement. Please