Dear All,
Please you may ignore my previous email. TWIN refinement in Refmac5 /
CCP4i2 worked well once used "HKLOUT_0-observed_data_asIMEAN.mtz" from the
data-reduction job. I am slowly getting used to the finer-aspects of
CCP4i2. Previously, I used to have both Intensities and Amplitudes in a
Dear All,
I have not had much experience in refining structure using data from
twinned crystals and has started using CCP4i2 very recently only.
Here is a background:
antigen-Fab crystal structure determined by MR first in P4(3)2(1)2 space
group with 1-complex molecule in the asymmetric unit
Hello Sir,
Just confirming PPI is Protein-Protein Interactions rather than Proton Pump
Inhibitors?
Anyway, I knew someone who used UCSF Chimera a lot for that sort of thing.
Hope this helps. Jon.C.
Sent from ProtonMail mobile
Original Message
On 25 Jan 2021, 19:02, Sergei
ICM PocketFinder might fit the bill (not free but academic license)
eg in
https://pubmed.ncbi.nlm.nih.gov/20977231/
Best, BR
From: CCP4 bulletin board On Behalf Of Sergei
Strelkov
Sent: Monday, January 25, 2021 11:02
To: CCP4BB@JISCMAIL.AC.UK
Subject: [ccp4bb] Characterising potential
Dear everyone,
In a drug discovery project where our aim is to interfere with some PPIs, we
could obtain binding of drug-like fragments in several potentially interesting
pockets on our target. We would like to make a projection on how promising
these individual pockets are. One way of doing
Dear Dr Xinlai Cheng,
My name is Mounika, have completed Masters in Biotechnology in the 2019
from Hyderabad India. I am writing this mail regarding any PhD positions
offered in your lab. I feel that pursuing PhD in onco biology would help me
reach my dream and also be among one who could try
I would like to draw your attention to the position below.
Please contact Andrew Roe or Olwyn Byron if interested.
RE: 3-year BBSRC funded project, University of Glasgow, Scotland, UK.
Post-doctoral project with Profs Olwyn Byron and Andrew Roe
A new twist on drug design: AdhE spirosomes as
Dear all,
We would like to inform you that the Call for Proposals (regular proposals) is
now open for DESY beamline P11 at the PETRA III synchrotron in Hamburg.
This call relates to remote and onsite access during the run period
August-December 2021.
The deadline for submission is
Hello,
We are looking for a motivated RA to join our Structural Biology Team at
Waltham, MA! The successful candidate would have rich experience working with
different biomolecules and is interested in using NMR to aid drug design.
Please apply by sending a cover letter and resumé to
Please see the post below
https://05174277-077d-4bd1-b8cf-4aa0f6343f4c.filesusr.com/ugd/cb0357_3761b0f8d8e84ca8b926c32a1b06147b.pdf
To unsubscribe from the CCP4BB list, click the following link:
Hello,
We are looking for a motivated RA to join our team at Waltham, MA! The
successful candidate would have rich experience working with different
biomolecules and is interested in using NMR to aid drug design. Please apply by
sending a cover letter and resumé to
Dear all,
We are happy to announce the "iNEXT-Discovery First Annual Scientific Meeting".
This online Zoom-event will take place on February 16th, 2021
The program, with presentations from iNEXT-Discovery partners and external
speakers, is open for everybody with interest in modern
3-year postdoctoral position in biophysics at the Institute for Structural
Biology, Grenoble, France.
Investigating structural dynamics of green-to-red photoconvertible fluorescent
proteins for the design of ultrastable variants.
The recruited candidate will investigate the structural
On top of what Eleanor mentioned, looking for about 160 S atoms with
anomalous signal to 3.9A will be VERY hard. If you manage actually
find those sites (or a good subset of them), the next density
modification step can also be very hard: jumping over that 3.5-4A
hurdle to get interpretable
14 matches
Mail list logo
