[ccp4bb] Deadline(19-sept ) for beamtime proposals at BM14/ESRF for Nov/Dec 2007

2007-09-12 Thread Martin A. Walsh
Dear all, please submit your proposals for next round of beamtime at BM14 to ensure you get beamtime during Nov/Dec Deadline for submission of online proposals is next Wednesday the 19th Sept. 2007 Link: http://www.esrf.fr/exp_facilit

[ccp4bb] Deadline(19-sept ) for beamtime proposals at BM14/ESRF for Nov/Dec 2007

2007-09-12 Thread Martin A. Walsh
Dear all –in case of confusion with earlier post, I re-post with correct dates for beamtime deadlines and period at BM14 for last run of year at ESRF! Apologies but at least this means I get to announce a second time this wonderful opportunity for you to come and collect great data and solve

Re: [ccp4bb] Covalently bound drug molecule

2007-09-12 Thread Eleanor Dodson
You need a LINK record in the PDB and a dictionary to describe the link. If you run the job from the GUI with Review Restraints, the program should write out a suitable dictionary to describe the link. Check the distances etc to see if you agree with them. You then use the extended pdb and

[ccp4bb] Deadline(19-sept ) for beamtime proposals at BM14/ESRF for Nov/Dec 2007

2007-09-12 Thread Martin A. Walsh
Dear all -in case of confusion I re-post with correct dates for beamtime deadlines and period at BM14 for last run of year at ESRF! Apologies but at least this means I get to announce this wonderful opportunity for you to come and collect great data and solve structures at BM14 during

[ccp4bb] Postdoctoral position in Durham

2007-09-12 Thread POHL E.
University of Durham (UK) Department of Chemistry Postdoctoral Research Associate (fixed-term) Applications are invited for a postdoctoral position in the newly established protein crystallography group of Dr. Ehmke Pohl at the Chemistry Department of Durham University. The research

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2007-09-12 Thread Kennedy, William Dexter
W. Dexter Kennedy, MD Beyond the Known Scientific Reality ۞ Discovery Associate Director, Clinical Pharmacology Merck Co., Inc. P.O. Box 100, UG4D-48 351 North Sumneytown Pike North Wales, PA 19454 * [EMAIL PROTECTED] *267-305-7095 * (267)-305-6382

[ccp4bb] post-doc position in Gif-sur-Yvette (France)

2007-09-12 Thread Marcel Knossow
STRUCTURAL BIOCHEMISTRY OF THE INTERACTION OF THE NEURONAL PROTEIN TAU WITH TUBULIN A post-doctoral fellowship is available immediately at the Laboratoire d'Enzymologie et Biochimie Structurales (LEBS), CNRS, Gif-sur-Yvette, France. The contract will be initially for a period of one year.

[ccp4bb] Postdoctoral Position in Structural Enzymology, University of Michigan

2007-09-12 Thread Ray Trievel
Postdoctoral Position in Structural Enzymology, University of Michigan, Ann Arbor, MI, USA A postdoctoral research position is available at the University of Michigan to study enzymes that regulate chromatin structure and function. The enzymes under investigation govern gene expression and

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2007-09-12 Thread Li, Ming
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Re: [ccp4bb] Covalently bound drug molecule

2007-09-12 Thread Joe Krahn
I was using X-PLOR at the time. I later switched to a PRESidue patch. I was not sure how many atoms must be added to a residue before a modified amino acid becomes a linked amino acid. The PDB seems a bit adverse to non-standard links. For example, why is NADP not two residues with a LINK? There

[ccp4bb] Postdoctoral Position for PHENIX development

2007-09-12 Thread Paul D. Adams
=== Lawrence Berkeley National Laboratory Computational Postdoctoral Fellow === Computational Postdoctoral Fellow Job ID:

[ccp4bb] Number of refinement parameters

2007-09-12 Thread Paul Paukstelis
A couple of basic questions concerning the number of refinement parameters: How do you come up with the number of parameters based on the number of atoms? I was under the impression it was simply the number of atoms times 4 (x,y,z,B), but I've seen some reported numbers that have left me

Re: [ccp4bb] Tough ligand to bind?

2007-09-12 Thread Marian Szebenyi
Nian, Have you considered pressure-freezing, the method developed by Sol Gruner's group at Cornell? If cryoprotectants are causing the problem, freezing under pressure reduces the need for them. It's also possible that your ligand is present but disordered in the crystal, and