[ccp4bb] Postdoctoral position – Brohawn lab at the University of California, Berkeley

2016-10-17 Thread Steve Brohawn
The Brohawn lab at UC Berkeley, Department of Molecular and Cell Biology and Helen Wills Neuroscience Institute, seeks an outstanding postdoctoral scientist with a strong background in structural biology to join our team. We study cellular electrical excitability and sensory transduction

[ccp4bb] Job opportunities at Astex Pharmaceuticals, Cambridge UK

2016-10-17 Thread Pamela Williams
The Molecular Sciences Group at Astex Pharmaceuticals integrates multiple structural & biophysical techniques for fragment based drug discovery (FBDD). The group is currently expanding these approaches to include single particle cryo-EM. We are looking for a single particle cryo-EM scientist

[ccp4bb] Instruct Biennial Structural Biology Meeting 2017

2016-10-17 Thread Claudia Alen Amaro
Dear All, Instruct Biennial Structural Biology Registrations open The third Instruct Biennial Structural Biology Meeting will take place in Brno, Czech Republic the 25-26^th of May 2017. Brno is the city of Johann Gregor Mendel, a founder of modern genetics and one of the first scientists who

Re: [ccp4bb] Teaching models and cognition w/ xtallography as example, high school lvl

2016-10-17 Thread Morten Grøftehauge
Thanks for the help all, I ended up using Protopedia for the list of Nobel Prizes but I really like the Oxygen We Breathe tutorial and I've bookmarked it for future use. In the end I had them read Ed Yong's article in The Atlantic about the inevitable evolution of bad science. We talked about

[ccp4bb] Antw: Re: [ccp4bb] Antw: Re: [ccp4bb] High B factor

2016-10-17 Thread Matthias Barone
In my feeling, lowering the occ explains much more such unordered loops (or solvent exposed sidechains..). B-factors are a measure of uncertainty of the atom position xyz: Letting B-factors fly is like broadening a distribution to an extent where the expectation value looses its purpose. That

Re: [ccp4bb] Antw: Re: [ccp4bb] High B factor

2016-10-17 Thread Tim Gruene
Dear Carlos and Phoebe, the B-value describes the movement of an atom at first order approximation, i.e. as a harmonic motion. It's very unlikely that an atom that is not visible in density, discribes a harmonic motion. It never occurred to me, but modelling disorder by strong B-factor

Re: [ccp4bb] Antw: Re: [ccp4bb] High B factor

2016-10-17 Thread Carlos CONTRERAS-MARTEL
Even that occupancy refinement seems to be very interesting for crystallographers, I complete agree with Phoebe. On 10/14/16 17:38, Phoebe A. Rice wrote: Interesting way to look at it. But those loop residues are really in the crystal with an occupancy of 1, so wouldn't letting the B factor

Re: [ccp4bb] Structural biology software that does not run on Windows or gives important Windows-specific problems

2016-10-17 Thread Mark J van Raaij
Summary that I am going to use to justify buying MacOSX instead of Windows (in case this is of use to others): Not available in Windows: ADXV for looking at crystallographic diffraction images XDS and HKL2000 for crystallographic data processing (Auto)SHARP for phasing ARPWARP for automated