Re: [ccp4bb] High top LLG, but low top TFZ

I am afraid that R factor is not encoutaging! How molecules in the asymmeric unit? Eleanor On Tue, 11 Jun 2019 at 01:03, Weixi Gu wrote: > Hi Eleanor, > Thank you for your answers. I just want to add more information. > The resolution is ~ 2A. The space group is P1. After phenix refine, Rwork >

Re: [ccp4bb] COOT crashes when I merge molecules

I also faced this problem. Manjula On Tue, 11 Jun 2019, 1:48 a.m. Tanner, John J., wrote: > Merging EDO into a structure also crashes in Coot 0.8.9.2 running on > linux. > > > John J. Tanner > Professor of Biochemistry and Chemistry > Department of Biochemistry > University of Missouri > 117 Sc

Re: [ccp4bb] High top LLG, but low top TFZ

Hi Eleanor, Thank you for your answers. I just want to add more information. The resolution is ~ 2A. The space group is P1. After phenix refine, Rwork decreases from 0.525 to 0.5175, but Rfree increases from 0.5239 to 0.5381. Is the high LLG, low TFZ because of the wrong or bad search model? Than

Re: [ccp4bb] W. Friedrich's thesis title

In the 2019 book Wilhelm Conrad Röntgen: The Birth of Radiology by Gerd Rosenbusch and Annemarie de Knecht-van Eekelen, there is a table of all the doctoral and/or habilitation students supervised by Röntgen. In this table, Walter Friedrich's dissertation is dated 24 July 1911 and carries the

Re: [ccp4bb] COOT crashes when I merge molecules

Merging EDO into a structure also crashes in Coot 0.8.9.2 running on linux. John J. Tanner Professor of Biochemistry and Chemistry Department of Biochemistry University of Missouri 117 Schweitzer Hall 503 S College Avenue Columbia, MO 65211 Phone: 573-884-1280 Email: tanne...@missouri.edu

Re: [ccp4bb] COOT crashes when I merge molecules

I'm having a similar issue with the same Coot version in both Ubuntu 18.04.2 LTS and Win 10 (WinCoot). Merging an added water crashes while an added K or PO4 does not. To unsubscribe from the CCP4BB list, click the followi

[ccp4bb] Single Crystal XRD Application Scientist (Neu-Isenburg, Germany)

POSITION: Single Crystal XRD Application Scientist LOCATION: Rigaku Europe SE, Application, Neu-Isenburg, Germany The successful candidate will provide application support for routine and complex crystallographic problems on single crystal X-ray diffraction instruments manufactured by Rigaku Cor

Re: [ccp4bb] High top LLG, but low top TFZ

Hardly enough information! Resolution? Wrong spacegroup - eg P21212 when it should be P212121 or something? Wrong estimate of model difference? That can afffect LLG quite a lot? But there are many reasons.. Does the Rfactor fall when you refine? A change of R=55% to R=47% usually indicates the

[ccp4bb] High top LLG, but low top TFZ

Dear all, I have been using Phaser for molecular replacement. One of the search models I tired generated 5 MR solutions. The best solution has a over 300 LLG value, but a low TFZ value (5). I checked the map in coot. The density and model didn't match well. I am wondering if it is normal? What's

[ccp4bb] 4-year PhD position at Biocenter Oulu

Dear colleagues, we have a 4-year PhD position available in our lab at the University of Oulu, Finland. The project will start in January 2020 and end in December 2023. The project will focus on two main topics: the structural basis of mutations causing human hereditary neuropathies and the mo

Re: [ccp4bb] W. Friedrich's thesis title

Hi folks Many thanks to Daniel for confirming this! It seems that both ccp4bb and wikipedia are my friends... Harry On 10 Jun 2019, at 11:23, Bonsor, Daniel wrote: > According to the German Wikipedia page it is correct. > https://de.m.wikipedia.org/wiki/Walter_Friedrich_(Biophysiker) > > Ma

Re: [ccp4bb] W. Friedrich's thesis title

According to the German Wikipedia page it is correct. https://de.m.wikipedia.org/wiki/Walter_Friedrich_(Biophysiker) Maybe it wasn't deposited in the library until 1912. Dan Get Outlook for Android From: CCP4 bulletin board on behalf of H

Re: [ccp4bb] W. Friedrich's thesis title

Hi folks I've found a thesis dated 1912 with the title "Intensitätsverteilung der X-Strahlen, die von einer Platinaantikathode ausgehen" - could anyone confirm if that's the one? All the other references I've found say it should be 1911, and a year in science (particularly at that time, when th

[ccp4bb] W. Friedrich's thesis title

Hi folksI've been trying to track down the title of Friedrich's (of Friedrich and Knipping fame) 1911 thesis at Ludwig-Maximilians Universität, München - all I can find is a translation into English. I don't want my personal (or google translate or similar) back in to German, so I was wondering if

[ccp4bb] MoRDa update

Dear All MoRDa is a pipeline for molecular replacement structure solution. A new update to the package is now available. The structure solution program is improved and database is extended . Both update and installation instructions are available from Morda homepage

[ccp4bb] Super Resolution Fluorescence Imaging

Dear all, I’d like to draw your attention to our forthcoming Super Resolution Fluorescence Microscopy symposium taking place at Diamond Light Source, on June 27th and 28th. The meeting will consist of short talks from developers in the field as well as extensive discussions on methods, instrum

[ccp4bb] PhD Positions in Milan

Dear All, I would like to draw your attention to the PhD Course in Molecular Medicine at the San Raffaele Vita-Salute University, now open for applications (https://www.unisr.it/en/offerta-formativa/medicina-chirurgia/post-lauream/dottorato-medicina-molecolare). A total of 40 positions are avai