Re: [ccp4bb] Figure of merit in refinement

2019-10-17 Thread Keller, Jacob
>>And as we often end our beer-discussions - may be all protein space groups >>are actually true P1, just close enough to satisfy the high symmetry rules .. >>but this is getting a bit philosophical I know .. Could we add that all crystals are twinned, just some are in such a way as to be a

[ccp4bb] Call for Stanford-SLAC Cryo-EM Center (S2C2) Applications: Deadline November 1, 2019

2019-10-17 Thread Dunn, Lisa B.
Dear All, The next deadline for submitting proposals to the Stanford-SLAC Cryo-EM Center (S2C2) is November 1, 2019. The missions of the Stanford-SLAC Cryo-EM Center (S2C2) are: 1. to provide access to state-of-the-art cryo-EM instruments for data collection towards atomic resolution

[ccp4bb] Job opening: Scientist-I (Structural Biology) at Frederick National Laboratory for Cancer Research

2019-10-17 Thread Dhirendra K Simanshu
Hello everyone, The Frederick National Laboratory for Cancer Research is looking for a Scientist with experience in protein chemistry and structural biology. The candidate will join the structural biology group within the NCI RAS Initiative program and work on the protein-small molecule

[ccp4bb] Job opening: Scientist, NMR/Structural Biology

2019-10-17 Thread Ying Zhang
Dear all, This post is to bring your attention to a job opportunity of a scientist position at Plexxikon Inc. We are looking for a highly motivated, structural biologist with expertise in NMR. Please help to distribute this to anyone that might be interested. Plexxikion is located in

Re: [ccp4bb] Issues in new Mac version 10.15

2019-10-17 Thread Charles Ballard - UKRI STFC
Dear All as has been pointed out, and as per usual, OS X updates seem to remove some of the setup for XQuartz, which will cause most X11 based apps to stop working. It is best to re-install XQuartz. This will work for an updated system that had CCP4 previously installed on it. We have had a

Re: [ccp4bb] Figure of merit in refinement

2019-10-17 Thread Jan Dohnalek
Dear all, regarding the "remaining strong differences" between measured data and calculated SFs from a a finished (high res structure) I once investigated a bit into this going back to images and looking up some extreme outliers. I found the same - those were clear strong diffraction spots, not

[ccp4bb] RFP for Small Molecule Discovery - AIMS Awards Deadline is October 28th

2019-10-17 Thread Nick DeHaan
Hi CCP4BB, The application deadline for the AIMS Awards program is less than two weeks away! For anyone with a solved protein structure, an AIMS Award can help you discover new small molecule binders. The program is open to investigators, postdocs, and graduate students worldwide. Applications