[ccp4bb] postdoctoral position at Birkbeck/UCL

[Nikos Pinotsis]

The Marechal group is looking to recruit a postdoctoral researcher to 
study the structure and function of the mitochondrial respiratory 
complex IV (cytochrome c oxidase). The position is funded for 3 years 
and it is immediately available.


Deadline for applications is the 14th of May 2020.

Details and on-line application can be found in the following link:

https://cis7.bbk.ac.uk/vacancy/postdoctoral-research-associate-417932.html

More information about our research can be found in our recent 
publications:


Marechal et al PNAS 2020 PMID:32291342
Hartley et al PNAS 2020 PMID: 32291341
Hartley et al Nat Struct Mol Biol 2019 PMID: 30598554

For informal enquires please contact Dr Amandine Maréchal (a.marechal  @ 
ucl.ac.uk).


--
Dr. Nikos Pinotsis
Protein Crystallography and Biophysics Centre
Institute of Structural and Molecular Biology
Department of Biological Sciences, Room B16b
Birkbeck College
Malet Street
London WC1E 7HX
T: +44 (0)207 631 6458
M: +44 (0)792 384 3593




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[ccp4bb] Mail-in protein-to-structure services at EMBL Grenoble HTX Lab to support research on COVID-19

[Jose A. Marquez]

*
*

*Mail-in protein-to-structure services at EMBL Grenoble HTX Lab to 
support research on COVID-19.*


The High throughput Crystallization Facility at EMBL Grenoble (HTX Lab) 
provides access to a fully automated protein-to-structure pipeline based 
on the CrystalDirect technology and the CRIMS software. This pipeline 
starts with mail-in samples and integrates crystallization screening, 
crystal optimization and automated harvesting in a continuous and fully 
automated workflow that can be operated by any scientist from a desktop 
computer with connection to the internet. The CRIMS software is able to 
communicate with the ESRF and Petra III synchrotrons to support 
automated and remote X-ray data collection and provides real-time access 
to experimental results and parameters. These capabilities are uniquely 
suited to support structural biology projects in conditions of 
confinement. The HTX lab is accepting projects on COVID-19 related 
research starting April 16th.


The HTX Lab also provides access to dedicated pipelines for the rapid 
analysis of protein-small molecule interactions as well as for large 
scale fragment screening to support development of inhibitors and 
chemical tools. This includes access to two fragment libraries (1200 and 
700 fragments respectively) and automated data processing for hit 
identification.


If you want to benefit from access to the HTX lab for COVID-19 research, 
please send an e-mail to h...@embl.fr indicating the project goals and a 
description of the samples you would be shipping.


Best regards

Jose A. Marquez

_

Jose A. Marquez Ph.D.
Team Leader, Head of the Crystallization Facility
EMBL Grenoble
Postal address: European Molecular Biology Laboratory
71, Avenue des Martyrs
CS 90181 38042 Grenoble Cedex 9, France
Delivery address: European Molecular Biology Laboratory
71, Avenue des Martyrs
38000 Grenoble, France
Phone +33 (0)476 20 74 25
Fax. +33 (0)476 20 71 99
https://embl.fr/htxlab/
_




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[ccp4bb] iNEXT-Discovery: Access to facilities for structural biology research

[Anastassis Perrakis]

Dear all,

While being in turbulent times, iNEXT-Discovery, the EC Horizon-2020 project 
offering access to facilities for structural biology (EM, NMR, X-rays and 
macromolecular biophysics), has officially started its operations. 
iNEXT-Discovery encourages applications for structural biology projects for 
‘translational research projects’ in the areas of biomedicine, biotechnology, 
biomaterials and in the food sector, in particular from non-experts and for 
researchers from academia and industry.

We are now happy to announce to the wider research community our new website 
with details about the project and where applications for access to the 
participating facilities can be submitted:

https://inext-discovery.eu

Regardless of current corona-measures external researchers are more than 
welcome to apply for access and we expect reviewing of incoming proposals to 
proceed as normal. However, please keep in mind that most facilities are 
currently not operational, and it is uncertain when they will open again to 
deliver access and to receive visitors. We will not be able to give a detailed 
overview about the status of all facilities, as the situation is changing 
almost daily.

Having accepted applications in our access pipelines will help both our 
scheduling and yours. Our facilities can arrange experiments for approved user 
projects to be executed immediately after local policies allow.

Please note that applications addressing SARS-CoV-2 or Covid-19 and mentioning 
this in the title will be funneled towards rapid review. Operational facilities 
will prioritize such projects if they can be accommodated.

On behalf of the iNEXT-Discovery team,

Hans Wienk (Project Manager) - email 
h.wienk.AT.nki.nl for questions about access
Anastassis Perrakis (Coordinator)








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