Very well said Frank.
And if the meeting really needs (why?) that regular dude to appear, they can
give a 20 min intro (same slides as last year, no doubt) and share the lectern
with a student / postdoc who presents the new science.
Marko
On 24 Jul 2020, 07:17, at 07:17, Frank von Delft
wrot
Thanks Stephen for reminding me there's a point no-one raised at the time:
There are two sets of people that have agency in this: 1) the
organisers, and 2) the ones that get the invites.
Group 1 already have a tough job: organising a meeting is a pile of
work - so go easy on them. (Or orga
... and don’t forget the Mg++ ion
Sent from my iPad
> On 23 Jul 2020, at 20:10, LMB wrote:
>
> One way of approaching such modelling uncertainties is to build explicitly a
> number of likely models, refine them and examine the difference maps
> carefully to see whether you can convince your
One way of approaching such modelling uncertainties is to build explicitly a
number of likely models, refine them and examine the difference maps carefully
to see whether you can convince yourself that one model is clearly better than
the others. At least then you will know whether the alternati
Dear Reza,
I would back Jon’s idea of looking at homologues, although
this does depend on how close the homologue is. For example, if your protein
has a “P” loop, with the Walker A sequence motif, then I think it would be very
surprising if the nucleotide bound in different wa
Dear all,
We’re looking for a 24 h.t. and 24 fil. power supply for a Phillips CM10
Electron Microscope. Does anyone know how to get such component separately?
Used is fine too.
Thanks,
J.
To unsubscribe from the CCP4BB list
Dear all,
The STFC Scientific Computing Department and ISIS neutron source are
looking for two programmer scientists, who will develop the next generation
of single-crystal neutron diffraction analysis software for the
time-of-flight technique. The software will extend the DIALS data
processing pa
Hi all,
The SGC-Toronto crystallography group is looking for a postdoctoral fellow.
Details can be found in the following link:
https://www.thesgc.org/careers/toronto/sgc-toronto-postdoctoral-position-structural-biology
Regards,
Levon
##
Tried the homologues thing. There are homologues and I've done the fitting, but
this is what I consider to be subjective. I'm certain the referee will ask:
Given the quality of density for the nucleotide, how certain are the authors
that a different fit is not possible? Have other fit poses been
Hello, do you have any homologues in the PDB with ATP, etc, bound as a guide?
Coot is pretty good at fitting known ligands, and unknown ones, too!
Original Message
On 23 Jul 2020, 17:53, Reza Khayat wrote:
> Hi,
>
> Can folks suggest programs for objectively docking ATP/ADP mol
Hi,
Can folks suggest programs for objectively docking ATP/ADP molecules into
density? Our density is not so good, probably because of occupancy, and we'd
like a less subjecting approach for modeling. Thanks.
Best wishes,
Reza
Reza Khayat, PhD
Assistant Professor
City College of New York
De
It has been on my mind to respond to this thread since I was made aware of it
in late February. Not because I regard myself as any sort of sage on these
matters, but because I received a phone call from someone asking me to speak
out. This person did not want to give her name and or to go into s
The Multiscale Research Institute for Complex Systems (MRICS) at Fudan
University is located at the Zhangjiang Campus of Fudan University and is
supported by the Shanghai High-level Talents Program. MRICS is strongly
committed to the development of novel and effective multi-scale imaging
techn
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