[ccp4bb] A community support letter for the “UK XFEL” project

2021-04-26 Thread Orville, Allen (DLSLtd,RAL,LSCI)
To whom it may concern, To explore the UK and International community appetite for a next generation XFEL we are conducting this survey to gather information and sample support for the UK XFEL project (which seeks to deliver such next generation capability). X-ray free electron lasers (XFELS)

[ccp4bb] Post-doctoral position available

2021-04-26 Thread Page,Rebecca
The Page Laboratory at the University of Connecticut Health Center has an immediate opening for up to two post-doctoral candidates to study pro- and eukaryotic signaling enzymes, with a focus on the function of phosphatases that form large signaling complexes, and also drug/inhibitor

[ccp4bb] Post doctoral position in structural biology of ER protein complexes

2021-04-26 Thread Kajander, Tommi A
Dear All, I’d like to draw your attention to open post doctoral position in our laboratory in Helsinki in biochemical and biophysical characterisation and structural biology of novel endoplasmic reticulum stress regulator protein complexes. Position is for one year initially with possibility

[ccp4bb] iUCR-25 takes place in August 2021

2021-04-26 Thread Eugene Krissinel - STFC UKRI
Dear All, We would like to draw your attention to the recent announcement from iUCR-25 organisers: https://mailchi.mp/909bcb8a8cd9/iucr25-prague-call-for-abstracts?e=e7b950fa73 Last 12 months may be confidently called as the "year online", and we wonder if there may be fresh submissions to

Re: [ccp4bb] Co crystalization with less soluble ligand.

2021-04-26 Thread David Briggs
These are my go-to review articles for ideas for getting a ligand into a crystal. https://scripts.iucr.org/cgi-bin/paper?S0907444906047020 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5297911/ I have also seen a talk where someone successfully dissolved their water-insoluble ligand in

Re: [ccp4bb] Co crystalization with less soluble ligand.

2021-04-26 Thread Bernhard Spingler
Dear Gourab, You might just want to add the ligand in pure, solid form to the edge of the crystallization drop. This worked in our case beautifully (see Angew. Chem. Int. Ed. 2012, 51, 3354). We had to soak it for 4 weeks. Good luck! Best regards Bernhard