Re: [ccp4bb] Measuring angles between domains

2021-11-13 Thread Eleanor Dodson
Well I do this by overlapping one domain of protein A onto protein B - you can do that in coot - then overlap the second domain of the shifted A onto the second domain of B. The coot log file tells you omega phi kappa applied and kappa is your angle of interest... is that clear enough - I could giv

Re: [ccp4bb] High-order oligomers vs robust crystals - references?

2021-11-13 Thread Amir Khan
Intuitively, when jagged and oddly-shaped proteins oligomerize, it would make sense they could fit better into a suitcase. > On Nov 12, 2021, at 9:52 AM, Frank von Delft > wrote: > > Hello all > > Two decades ago, I remember (!) much talk about a reason that bacterial > proteins crystallize

Re: [ccp4bb] High-order oligomers vs robust crystals - references?

2021-11-13 Thread orly avraham
Hi, I think this paper might be useful for digging into oligomerization and crystallization: https://onlinelibrary.wiley.com/doi/pdf/10.1002/anie.201806092 I'm not sure they discuss prokaryotes but do have many interesting ideas. Best, Orly On Fri, Nov 12, 2021 at 7:20 PM Edwin Pozharski wro

[ccp4bb] Open position: Structural Bioinformatics Pipeline Developer at Lonza (Cambridge UK)

2021-11-13 Thread Daphne Truan
Hi All, We are hiring again! Know someone that wants to join a fast growing team? We are seeking a highly motivated and skilled developer with experience in implementing structural bioinformatics tools/pipelines to join Lonza's Early Development Services (EDS) Bioinformatics team based in Cambr