[ccp4bb] PDRA position in the University of Liverpool (UK)

[Antonyuk, Svetlana]

UNIVERSITY OF LIVERPOOL
DEPARTMENT OF BIOCHEMISTRY AND SYSTEMS BIOLOGY
Cryo-EM STRUCTURAL BIOLOGY POSTDOCTORAL RESEARCH ASSOCIATE


Grade 7 (Salary range £38,250 - £40,521 pa)

An exciting opportunity has emerged to join the Molecular Biophysics 
Group to work on a BBSRC-supported 
collaborative project between the teams from University of Leeds and Liverpool 
aimed at answering fundamental questions on enzyme mechanism of quinol- 
dependent integral membrane nitric oxide reductases, a member of respiratory 
heme- copper oxidase superfamily. The project builds on our recent 2.2Å cryoEM 
structure of this enzymeand aims to address a number of ambitious questions 
through well-informed point mutations and high resolution cryoEM structures. In 
addition to the isolated enzyme, we also aim to obtain the first structures of 
CuNiR-qNOR protein-protein complexes in catalytic turnover.

We require an experienced PDRA with fluency in several elements of a structural 
biology project including cryoEM data collection and processing, model building 
and structure refinement at high resolutions. Experience with protein 
expression and purification of membrane proteins is desirable. The PDRA will be 
assisted by a full-time research associate/research technician for producing 
wild-type and mutant qNOR membrane bound proteins in sufficient quantities for 
functional and cryoEM studies. The RA would also support in producing CuNIRs 
and its mutants following the established protocols in our laboratories.

You should also be able to work in a team and previous experience of working at 
multiple sites would be an advantage. The PDRA is expected to spend significant 
time (typically one week per month) at Leeds where you would be fully 
integrated into Muench’s group. Excellent verbal and written communication 
skills are essential. Closing date for application is 30th March 2024. The post 
is available for immediate start for nearly 3 years.



Please send your CV and cover letter to Professor Samar Hasnain 
(s.s.hasn...@liverpool.ac.uk), Dr Stephen 
Muench (s.p.mue...@leeds.ac.uk) and Dr Svetlana 
Antonyuk (s.anton...@liverpool.ac.uk)



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[ccp4bb] Position is available (University of Liverpool, UK)

[Antonyuk, Svetlana]

UNIVERSITY OF LIVERPOOL
DEPARTMENT OF BIOCHEMISTRY AND SYSTEMS BIOLOGY

Cryo-EM STRUCTURAL BIOLOGY POSTDOCTORAL RESEARCH ASSOCIATE

Grade 7 (Salary range £38,250 - £40,521 pa)


An exciting opportunity has emerged to join the Molecular Biophysics 
Group to work on a BBSRC-supported 
collaborative project between the teams from University of Leeds and Liverpool 
aimed at answering fundamental questions on enzyme mechanism of 
quinol-dependent integral membrane nitric oxide reductases, a member of 
respiratory heme-copper oxidase superfamily. The project builds on our recent 
2.2Å cryoEM structure of this enzyme and aims to address a number of ambitious 
questions through well-informed point mutations and high resolution cryoEM 
structures. In addition to the isolated enzyme, we also aim to obtain the first 
structures of CuNiR-qNOR protein-protein complexes in catalytic turnover.

We require an experienced PDRA with fluency in several elements of a structural 
biology project including cryoEM data collection and processing, model building 
and structure refinement at high resolutions. Experience with protein 
expression and purification of membrane proteins is desirable. The PDRA will be 
assisted by a full-time research associate/research technician for producing 
wild-type and mutant qNOR membrane bound proteins in sufficient quantities for 
functional and cryoEM studies. The RA would also support in producing CuNIRs 
and its mutants following the established protocols in our laboratories.
You should also be able to work in a team and previous experience of working at 
multiple sites would be an advantage. The PDRA is expected to spend significant 
time (typically one week per month) at Leeds where you would be fully 
integrated into Muench’s group. Excellent verbal and written communication 
skills are essential. The post is available for immediate start for nearly 3 
years.

Please send your CV and cover letter to Professor Samar Hasnain 
(s.s.hasn...@liverpool.ac.uk), Dr Stephen 
Muench (s.p.mue...@leeds.ac.uk) and Dr Svetlana 
Antonyuk (s.anton...@liverpool.ac.uk)



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[ccp4bb] Postdoctoral position is available in the laboratory of Dr Igor Barsukov (University of Liverpool UK)

[Antonyuk, Svetlana]

Postdoctoral Position in Structural Biology of Cell-Matrix Adhesion

We are currently recruiting for a 3-year postdoctoral position in the field of 
Structural Biology of Cell-Matrix Adhesion at the Biochemistry and Cell Biology 
department of Liverpool University, UK. This position is funded by the BBSRC 
and offers a unique opportunity to contribute to cutting-edge research in the 
laboratory of Dr. Igor Barsukov.

As a successful candidate, you will have a strong background and expertise in 
either protein NMR spectroscopy or X-ray crystallography. Your primary focus 
will be on studying the structure and function of protein complexes involved in 
the formation of cell-matrix fibrillar adhesions, which play a crucial role in 
tissue formation, integrity, and regeneration. Recent research in our 
laboratory has highlighted the regulatory role of the adaptor protein tensin in 
fibrillar adhesions, particularly through its interactions with integrins and 
other proteins within the adhesion complexes. However, the precise mechanisms 
underlying this regulation, particularly the ability of tensin to form 
molecular condensates through phase separation, are not fully understood. In 
this position, you will utilize a wide range of biophysical techniques and 
advanced protein modifications to investigate the molecular details of tensin 
condensation and its interaction with integrin and other adhesion proteins.

Our department offers a supportive and technology-rich research environment for 
structural biology and biochemistry. This includes access to state-of-the-art 
facilities such as a High-Field NMR facility equipped with 600, 700, and 800 
MHz spectrometers with high-sensitivity cryo probes. We also have a Barkla 
X-ray crystallography facility with regular access to powerful synchrotron 
radiation facilities, as well as a protein analysis facility with advanced 
instruments for studying protein interactions.

To be considered for this position, you should hold a PhD degree in Biological 
Sciences or Chemistry. The post is available for a duration of 3 years. For 
more information, please contact Dr. Igor Barsukov at i...@liverpool.ac.uk.

To apply for this position and for more detailed information, please visit 
http://tinyurl.com/5e35csak. The closing date for applications is 15-Feb-2024





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[ccp4bb] Research Assistant (Structural Biology of Membrane Proteins) opportunity in the University of Liverpool, UK

[Antonyuk, Svetlana]

Dear members of the community,


An exciting opportunity has emerged to join the Molecular Biophysics Group to 
work on a BBSRC-supported collaborative project between the teams from 
University of Leeds and Liverpool aimed at answering fundamental questions on 
enzyme mechanism of quinol-dependent integral membrane nitric oxide reductases, 
a member of respiratory heme-copper oxidase superfamily. The project builds on 
our recent 2.2Å cryoEM structure of this enzyme and aims to address a number of 
ambitious questions through well-informed point mutations and high resolution 
cryoEM structures. In addition to the isolated enzyme, we also aim to obtain 
the first structures of CuNiR-qNOR protein-protein complexes in catalytic 
turnover.

We require a research assistant at Liverpool to support an experienced PDRA and 
the team for this project. You will be responsible for producing wild-type and 
mutant qNOR membrane bound proteins in sufficient quantities for functional and 
cryoEM studies. You would also support in producing CuNIRs and their mutants 
following the established protocols in our laboratories.

You should also be able to work in a team. You will have significant experience 
in membrane protein purification. You will be provided with a range of training 
opportunities including attending workshops and where appropriate conferences.  
You will have a degree in a relevant subject area.

This post is available from 1 October 2023 until 30 September 2026.

The University has the right to close the vacancy early if it is deemed that 
there have been enough applications received.

Job Ref: 063226 
Closing Date: 28 August 2023

For full details and to apply online, please visit:

https://www.jobs.ac.uk/job/DBW146/research-assistant-structural-biology-of-membrane-proteins



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[ccp4bb] Postdoctoral Research Associate (Cryo-EM STRUCTURAL BIOLOGY) position in the University of Liverpool, UK. (Job reference 062046)

[Antonyuk, Svetlana]

Dear colleagues,

An exciting opportunity has emerged to join the Molecular Biophysics Group to 
work on a BBSRC-supported collaborative project between the teams from 
University of Leeds and Liverpool aimed at answering fundamental questions on 
enzyme mechanism of quinol-dependent integral membrane nitric oxide reductases, 
a member of respiratory heme-copper oxidase superfamily. The project builds on 
our recent 2.2Å cryoEM structure of this enzyme and aims to address a number of 
ambitious questions through well-informed point mutations and high resolution 
cryoEM structures. In addition to the isolated enzyme, we also aim to obtain 
the first structures of CuNiR-qNOR protein-protein complexes in catalytic 
turnover.

We require an experienced PDRA with fluency in several elements of a structural 
biology project including cryoEM data collection and processing, model building 
and structure refinement at high resolutions. Experience with protein 
expression and purification of membrane proteins is desirable. The PDRA will be 
assisted by a full-time research associate/research technician for producing 
wild-type and mutant qNOR membrane bound proteins in sufficient quantities for 
functional and cryoEM studies. The RA would also support in producing CuNIRs 
and its mutants following the established protocols in our laboratories.

You should also be able to work in a team and previous experience of working at 
multiple sites would be an advantage. The PDRA is expected to spend significant 
time (typically one week per month) at Leeds where you would be fully 
integrated into Muench's group. Excellent verbal and written communication 
skills are essential.

This post is available until 30 September 2026.
Please apply via https://bit.ly/062046

You will have a PhD in Structural Biology.

Any applicants who are still awaiting their PhD to be awarded should be aware 
that if successful, they will be appointed at grade 6, spine point 30.  Upon 
written confirmation that they have been successful in being awarded their PhD, 
they will be moved onto grade 7, spine point 31 (£38,205 - £40,521 pa) from the 
date of their award.

The University has the right to close the vacancy early if it is deemed that 
there have been enough applications received

For informal enquires please e-mail Prof. Samar Hasnain 
(ss...@liverpool.ac.uk) or Dr. Svetlana Antonyuk 
(s.anton...@liverpool.ac.uk)




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[ccp4bb] Two PDRA positions (36 months from October 23) at the University of Liverpool, UK

[Antonyuk, Svetlana]

Two PDRA positions (36 months from October 23) at the University of Liverpool

We have a Chemistry PDRA and a Biophysics-structural biology PDRA positions to 
develop non-covalent binders to SOD1 suitable as PROTAC degraders for the 
treatment of motor neuron disease association. The Chemistry PDRA position 
would be based in Chemistry department (Professor O’Neill/Dr Nixon), The second 
PDRA would be based in the Biosciences complex (Professor Samar Hasnain/Dr 
Antonyuk/Dr. Awais). The project will benefit from collaboration with leading 
PROTAC expert at Dundee (Ciulli) and team at the Alzheimer's Research UK UCL 
Drug Discovery Institute (ARUK UCL DDI) led by Fiona Ducotterd. We aim to 
provide novel scaffolds that bind to the as-yet unexploited validated pocket 
surrounding Trp32. We will investigate for the first time, a fragment-based 
approach to drug design targeted against destabilised SOD-1. Direct 
crystallographic visualisation will be used to undertake lead optimisation and 
designing of CNS penetrant versions of initial small molecules hits. This 
non-covalent binding is suitable for a PROTAC approach. In-cell visualisation 
of aggregation and cell death would be undertaken using confocal microscopy. 
Applicants with relevant experience are encouraged to make informal enquiries 
via email to s.s.hasn...@liverpool.ac.uk, 
pmone...@liverpool.ac.uk and 
s.anton...@liverpool.ac.uk



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[ccp4bb] Research Technician for a membrane protein project (University of Liverpool, UK)

[Antonyuk, Svetlana]

UNIVERSITY OF LIVERPOOL
DEPARTMENT OF BIOCHEMISTRY AND SYSTEMS BIOLOGY

Research Technician for a membrane protein project

£33,314-35,333 pa


An exciting opportunity has emerged to join the Molecular Biophysics 
Group to work on a BBSRC-supported 
collaborative project between the teams from University of Leeds and Liverpool 
aimed at answering fundamental questions on enzyme mechanism of 
quinol-dependent integral membrane nitric oxide reductases, a member of 
respiratory heme-copper oxidase superfamily. The project builds on our recent 
2.2Å cryoEM structure of this enzyme and aims to address a number of ambitious 
questions through well-informed point mutations and high resolution cryoEM 
structures. In addition to the isolated enzyme, we also aim to obtain the first 
structures of CuNiR-qNOR protein-protein complexes in catalytic turnover.

We require a research technician at Liverpool to support an experienced PDRA 
and the team for this project. Your will be responsible for producing wild-type 
and mutant qNOR membrane bound proteins in sufficient quantities for functional 
and cryoEM studies. You would also support in producing AxCuNIR and its mutants 
following the established protocols in our laboratories.
You should also be able to work in a team. We will provide the technician with 
a range of training opportunities including attending workshops and where 
appropriate conferences.  The University has a comprehensive promotion pathway 
for specialist technical support staff. The post is available for 3 years.

Please send your CV with a detailed cover letter explaining your suitability to 
Dr Stephen Muench (s.p.mue...@leeds.ac.uk), Dr 
Svetlana Antonyuk (anton...@liverpool.ac.uk) 
and Professor Samar Hasnain 
(s.s.hasn...@liverpool.ac.uk). The position 
is available from October 2023.



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[ccp4bb] Cryo-EM STRUCTURAL BIOLOGY POSTDOCTORAL RESEARCH ASSOCIATE position (University of Liverpool, UK)

[Antonyuk, Svetlana]

UNIVERSITY OF LIVERPOOL
DEPARTMENT OF BIOCHEMISTRY AND SYSTEMS BIOLOGY

Cryo-EM STRUCTURAL BIOLOGY POSTDOCTORAL RESEARCH ASSOCIATE

£38,250 - £40,521 pa


An exciting opportunity has emerged to join the Molecular Biophysics 
Group to work on a BBSRC-supported 
collaborative project between the teams from University of Leeds and Liverpool 
aimed at answering fundamental questions on enzyme mechanism of 
quinol-dependent integral membrane nitric oxide reductases, a member of 
respiratory heme-copper oxidase superfamily. The project builds on our recent 
2.2Å cryoEM structure of this enzyme and aims to address a number of ambitious 
questions through well-informed point mutations and high resolution cryoEM 
structures. In addition to the isolated enzyme, we also aim to obtain the first 
structures of CuNiR-qNOR protein-protein complexes in catalytic turnover.

We require an experienced PDRA with experience in several elements of a 
structural biology project including protein expression and purification of 
membrane metalloproteins, model building and structure refinement, cryoEM data 
collection and processing as well as some understanding of the biological 
systems and enzyme mechanism. The PDRA will be assisted by a full-time 
technician for producing wild-type and mutant qNOR membrane bound proteins in 
sufficient quantities for functional and cryoEM studies. The technician would 
also support in producing AxCuNIR and its mutants following the established 
protocols in our laboratories.
You should also be able to work in a team and previous experience of working at 
multiple sites would be an advantage. The PDRA is expected to spend a week per 
month at Leeds where you would be fully integrated into Muench’s group. 
Excellent verbal and written communication skills are essential. The post is 
available for 3 years.

Please send your CV with a detailed cover letter explaining your suitability to 
Dr Stephen Muench (s.p.mue...@leeds.ac.uk), Dr 
Svetlana Antonyuk (anton...@liverpool.ac.uk) 
and Professor Samar Hasnain 
(s.s.hasn...@liverpool.ac.uk). The position 
is available from October 2023.



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[ccp4bb] Postdoctoral Research Associate position in Liverpool (corrected)

[Antonyuk, Svetlana]

Postdoctoral Research Associate
University of Liverpool - Department of Cardiovascular and Metabolic Medicine
Location:   Liverpool
Salary: £34,810 to £40,322 p.a.
Hours:  Full Time
Contract Type:  Fixed-Term/Contract
Placed On:  25th August 2021
Closes: 21st September 2021
Job Ref:033448



We are looking for an enthusiastic Post-doctoral Research Associate to join the 
team of Dr Nordine Helassa on a 3-year British Heart Foundation funded project. 
Hypertrophic cardiomyopathy (HCM) is an autosomal dominant disease that can 
cause life-threatening cardiac arrythmias. It is the most common cause of 
sudden death in the young and is characterised by ventricular hypertrophy and 
contractile dysfunction. HCM has been associated with mutations in genes mostly 
encoding sarcomeric proteins such as myosin, tropomyosin and troponins. 
However, the detailed molecular mechanism leading to the clinical phenotype 
remains unclear. The project aims to determine the role of disease-associated 
troponin I mutations in cardiac dysfunction using a multidisciplinary approach 
combining protein biophysics, structural biology and muscle physiology.

You will have (or have already submitted) a PhD in structural biology, 
biochemistry, biophysics, biological sciences or a closely allied discipline. 
Laboratory experience with recombinant protein expression/purification 
techniques and structural biology (X-ray and/or NMR) would be advantageous. The 
post is available until 30 November 2024.

For full details and to apply online, please visit: 
https://recruit.liverpool.ac.uk



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[ccp4bb] Postdoctoral Research Associate position in Liverpool

[Antonyuk, Svetlana]

Postdoctoral Research Associate
University of Liverpool - Department of Cardiovascular and Metabolic Medicine
Location:   Liverpool
Salary: £34.81 to £40,322 p.a.
Hours:  Full Time
Contract Type:  Fixed-Term/Contract
Placed On:  25th August 2021
Closes: 21st September 2021
Job Ref:033448



We are looking for an enthusiastic Post-doctoral Research Associate to join the 
team of Dr Nordine Helassa on a 3-year British Heart Foundation funded project. 
Hypertrophic cardiomyopathy (HCM) is an autosomal dominant disease that can 
cause life-threatening cardiac arrythmias. It is the most common cause of 
sudden death in the young and is characterised by ventricular hypertrophy and 
contractile dysfunction. HCM has been associated with mutations in genes mostly 
encoding sarcomeric proteins such as myosin, tropomyosin and troponins. 
However, the detailed molecular mechanism leading to the clinical phenotype 
remains unclear. The project aims to determine the role of disease-associated 
troponin I mutations in cardiac dysfunction using a multidisciplinary approach 
combining protein biophysics, structural biology and muscle physiology.

You will have (or have already submitted) a PhD in structural biology, 
biochemistry, biophysics, biological sciences or a closely allied discipline. 
Laboratory experience with recombinant protein expression/purification 
techniques and structural biology (X-ray and/or NMR) would be advantageous. The 
post is available until 30 November 2024.

For full details and to apply online, please visit: 
https://recruit.liverpool.ac.uk



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[ccp4bb] Fully funded 4 year PhD position is available at University of Liverpool,UK/RIKEN, Japan

[Antonyuk, Svetlana]

Dear all,
Applications are invited for fully funded PhD studentship position in the 
laboratory of Prof Samar Hasnain (Liverpool,UK) in collaboration with Dr Masaki 
Yamamoto, Harima, RIKEN, Japan. The project involves the X-ray crystallography 
and X-ray Free-Electron laser study of proteins involved in denitrification in 
pathogenic bacteria and synthetic biology of these proteins.
Candidates should have a first or upper second class degree in Biochemistry, 
Biophysics or Chemistry. The successful candidate will have the opportunity to 
work 2 years at Harima Riken during their studentship.
The studentship is available to UK nationals or EU students who meet the UK 
residency requirements.To apply, please send a CV and cover letter to 
s.hasn...@liverpool.ac.uk The closing date 
for applications is April 30th, 2018
Best regards,

Svetlana


Dr. Svetlana Antonyuk
Reader
Co-Director of Barkla X-ray Laboratory of Biophysics
Institute of Integrative Biology
Faculty of Health and Life Sciences
University of Liverpool
Life Sciences Building
Liverpool
L69 7ZB
--
Phone:   +44(0)151-795 5145
Email:   s.anton...@liverpool.ac.uk

http://www.biophysics.liv.ac.uk/

[ccp4bb] 2 year BBSRC funded PDRA position at the University of Liverpool, UK

[Antonyuk, Svetlana]

THE UNIVERSITY OF LIVERPOOL
FACULTY OF HEALTH AND LIFE SCIENCES
INSTITUTE OF INTEGRATIVE BIOLOGY
DEPARTMENT OF BIOCHEMISTRY
POSTDOCTORAL RESEARCH ASSOCIATE GRADE 7
£32,958 - £34,956 pa
An exciting opportunity has emerged in the Molecular 
Biophysics group to work on a BBSRC-supported 
project on structure-function-mechanism studies of Cu-nitrite reductase and 
membrane bound nitric oxide (NO) reductase and the role of metabolon complex 
formation in controlling levels of cytotoxic NO. The project will link 
crystallographic studies with techniques to probe factors that control delivery 
of electrons and protons to the active site of these enzymes. You will be 
responsible for using established molecular biology procedures underpinning the 
overexpression and purification of a number of enzymes and their mutants 
including membrane proteins and undertake crystallographic, spectroscopic and 
mechanistic aspects of the programme. You will have the opportunity to spend up 
to 4 weeks in the RIKEN laboratories in Japan as part of a collaborative 
programme alongside two PhD students working on membrane-bound nitric oxide 
reductases. You should have a PhD in the area of physics, chemistry, biological 
sciences or biophysics, with experience in protein crystallography and 
practical knowledge of molecular biology preferably with experience in membrane 
proteins. Excellent verbal and written communication skills are essential. The 
post is available for 2 years and the ability to commence immediately would be 
advantageous.

Job Ref: 006744 
Closing Date: 11 April 2017

For full details and to apply online, please visit: 
https://recruit.liverpool.ac.uk

[ccp4bb] 2 year PDRA position in University of Liverpool UK

[Antonyuk, Svetlana]

THE UNIVERSITY OF LIVERPOOL
FACULTY OF HEALTH AND LIFE SCIENCES
INSTITUTE OF INTEGRATIVE BIOLOGY
DEPARTMENT OF BIOCHEMISTRY
 POSTDOCTORAL RESEARCH ASSOCIATE GRADE 7
 £32,958 - £34,956 pa
An exciting opportunity has emerged in the Molecular 
Biophysics group to work on a BBSRC-supported 
project on structure-function-mechanism studies of Cu-nitrite reductase and 
membrane bound nitric oxide (NO) reductase and the role of metabolon complex 
formation in controlling levels of cytotoxic NO. The project will link 
crystallographic studies with techniques to probe factors that control delivery 
of electrons and protons to the active site of these enzymes. You will be 
responsible for using established molecular biology procedures underpinning the 
overexpression and purification of a number of enzymes and their mutants 
including membrane proteins and undertake crystallographic, spectroscopic and 
mechanistic aspects of the programme. You will have the opportunity  to spend 
up to 4 weeks in the RIKEN laboratories in Japan as part of a collaborative 
programme alongside two PhD students working on membrane-bound nitric oxide 
reductases
You should have a PhD in the area of physics, chemistry, biological sciences or 
biophysics, with experience in protein crystallography and practical knowledge 
of molecular biology preferably with experience in membrane proteins. Excellent 
verbal and written communication skills are essential. The post is available 
until 31 March 2019.

Job Ref: 005185 
  Closing Date: 23 February 2017

For full details and to apply online, please visit: 
https://recruit.liverpool.ac.uk

Dr. Svetlana Antonyuk
Senior Lecturer
Co-Director of Barkla X-ray Laboratory of Biophysics
Institute of Integrative Biology
Faculty of Health and Life Sciences
University of Liverpool
Life Sciences Building
Liverpool
L69 7ZB
--
Phone:   +44(0)151-795 5145
Email:   s.anton...@liverpool.ac.uk

http://www.biophysics.liv.ac.uk/

[ccp4bb] Crystallography Symposium, 17th July 2015, Life Sciences Building, Lecture Theatre 3, University of Liverpool

[Antonyuk, Svetlana]

Dear all,

A symposium at the University of Liverpool has been organized to celebrate the 
achievements of Lipson and Beevers in the presence of a number of members of 
Lipson's family.

The event, which will take place on 17 July 2015, is free to attend. Speakers 
include Eleanor Dodson, Mike Glazer, Stephen Lipson, Hod Lipson and Peter 
Strickland. There is no registration fee. Registration is required for the 
event at 

http://payments.liv.ac.uk/browse/product.asp?compid=1modid=2catid=77


--

Crystallography Symposium, 17th July 2015, Life Sciences Building,

Lecture Theatre 3, University of Liverpool

 

Barkla X-ray laboratory of Biophysics was opened on 21st July 2011 by Sir Tom 
Blundell and Late Dame Louise Johnson. Charles Glover Barkla was a graduate and 
then a lecturer at the University. He made key contributions to the birth of 
X-ray physics and crystallography 
(http://www.biophysics.liv.ac.uk/X-rays_Liverpool.html), for which he received 
the 1917 Nobel Prize in physics. Arnold Beevers and Henry Lipson, who were also 
student and staff at Liverpool in the 1930’s invented the Beevers-Lipson strips 
which became the workhorse of crystallographic calculations (Fourier synthesis) 
prior to the emergence of calculating machines and computers in the 1960’s. A 
symposium is organized to celebrate the achievements of Lipson  Beevers in the 
presence of a number of family members of Henry Lipson. An X-ray exhibition 
will be opened at the end of the symposium celebrating the achievements of Sir 
Oliver Lodge (the first Physics Professor of the University, 1881), Barkla, 
Beevers  Lipson.

   

10:30-11:30  Session One   Chair: Professor Anthony Hollander, Director 
IIB

10:30-10:40  Welcome: Professor Samar Hasnain, Max Perutz Professor of 
Molecular Biophysics

10.40-11:10 Eleanor Dodson, FRS (University of York)  

Fourier Maps I have known; from Beevers-Lipson strips to Winograd Fast Fourier 
Transforms

11:10-11:20 Peter Strickland (IUCr’s Executive Managing Editor)

Lipson  IUCr

11:20-12:30 Session Two   Chair: Prof Stephen Holloway, Pro-Vice 
Chancellor

11:20-11:45  Mike Glazer, Vice President of IUCr (Oxford University)

Role of Lipson in Crystallography

11:45-12:10 Stephen Lipson (Technion, Israel)

My youth with Fourier Strips

12:10-12:30  Hod Lipson (Cornell/Columbia)

Fourier Strips: The dawn of bioinformatics

VOTE OF THANKS  GROUP PHOTO

 12:40  Professor Janet Beer, Vice Chancellor will open the X-ray exhibition 
celebrating the achievements of Barkla, Beevers, Lipson and Lodge at Liverpool

 12:40- 14:00 LUNCH  DEPARTURE

 Registration is free but requires registration at www.payments.liv.ac.uk 

 

Organisers: Dr Svetlana Antonyuk  Prof Samar Hasnain

[ccp4bb] Complementary Non-diffraction Techniques in Structural Biology, 11th December 2014, Brunei Gallery , SOAS, Russell Square, London

[Antonyuk, Svetlana]

  2014 BBS Symposium

Complementary Non-diffraction Techniques in Structural Biology
A one-day symposium to celebrate the end of the
UN International Year of crystallography 2014

Date: 11th December 2014 - from 10.30 to 16.30
Venue: Brunei Gallery , SOAS, Russell Square, London WC1H 0XG

Anthony Wattshttp://www.bioch.ox.ac.uk/aspsite/index.asp?pageid=603 - 
Chairman, British Biophysical Society
Speakers:

Olwyn Byron - University of 
Glasgowhttp://www.gla.ac.uk/schools/lifesciences/staff/olwynbyron/
Richard Henderson - MRC Laboratory of Molecular Biology, 
Cambridgehttp://www2.mrc-lmb.cam.ac.uk/group-leaders/h-to-m/richard-henderson/
Steve Matthews - Imperial College, 
Londonhttp://www.imperial.ac.uk/AP/faces/pages/read/Home.jsp?person=s.j.matthews_adf.ctrl-state=9rrq8kgsf_3
Sheena Radford - University of 
Leedshttp://www.astbury.leeds.ac.uk/people/staff/staffpage.php?StaffID=SER
Carol Robinson - University of 
Oxfordhttp://research.chem.ox.ac.uk/carol-robinson.aspx
Mark Sansom - University of 
Oxfordhttp://www.bioch.ox.ac.uk/aspsite/index.asp?pageid=599
John Walker - University of 
Cambridgehttp://www.mrc-mbu.cam.ac.uk/people/walker
Bonnie Wallace, Birkbeck College http://people.cryst.bbk.ac.uk/%7Eubcg25a/

To register for the symposium please choose one of the options below:

  *   BBS Members, £10 
http://www.oxforduniversitystores.co.uk/browse/extra_info.asp?compid=1modid=1prodid=9273

  *   Non-members of the BBS, 
£40http://www.oxforduniversitystores.co.uk/browse/extra_info.asp?compid=1modid=1prodid=9274

  *   Speaker / Honorary  member, no 
chargehttp://www.oxforduniversitystores.co.uk/browse/extra_info.asp?compid=1modid=1prodid=9278

payable in advance before 21 November 2014.

This fee includes a hot buffet lunch and refreshments for all registered 
participants.

To become a member of the BBS (£25 annual membership), please complete the 
applications forms found 
herehttp://britishbiophysics.org.uk/index.php?id=join.

--

Dr. Svetlana Antonyuk
Senior Lecturer
Institute of Integrative Biology
University of Liverpool
Biosciences Building
Liverpool
L69 7ZB
--
Phone:   +44(0)151-795 0349
Email:s.anton...@liverpool.ac.ukmailto:s.anton...@liverpool.ac.uk

[ccp4bb] Postdoctoral research associate position in structural biology at the University of LIverpool

[Antonyuk, Svetlana]

THE UNIVERSITY OF LIVERPOOL

FACULTY OF HEALTH AND LIFE SCIENCES
INSTITUTE OF INTEGRATIVE BIOLOGY
DEPARTMENT OF BIOCHEMISTRY

POSTDOCTORAL RESEARCH ASSOCIATE

£31,644 - £36,661 pa

An exciting opportunity has emerged to join the Molecular Biophysics Group to 
work on a BBSRC-supported project on structure-function-mechanism studies of 
Cu-nitrite reductase and membrane bound nitric oxide (NO) reductase and the 
role of metabolon complex formation in controlling levels of cytotoxic NO. The 
project will link crystallographic studies with techniques to probe factors 
that control delivery of electrons and protons to the active site of these 
enzymes. You will be responsible for using established molecular biology 
procedures underpinning the overexpression and purification of a number of 
enzymes and their mutants including membrane proteins and undertake 
crystallographic, spectroscopic and mechanistic aspects of the programme. You 
will have a chance to spend up to 4 weeks in the RIKEN laboratories in Japan as 
part of a collaborative programme alongside two PhD students working on 
membrane-bound nitric oxide reductases.

You should have a PhD in a relevant area, with experience in protein 
crystallography and practical knowledge of molecular biology. Experience in 
membrane proteins is desirable. Excellent verbal and written communication 
skills are essential. The post is available for 3 years initially.

Job Ref: R-584998   Closing Date: 30 March 2014

For full details, or to request an application pack, visit 
www.liv.ac.uk/working/job_vacancies/http://www.liv.ac.uk/working/job_vacancies/
or e-mail j...@liv.ac.ukmailto:j...@liv.ac.uk, please quote Job Ref in all 
enquiries

Dr. Svetlana Antonyuk
Senior Lecturer
Institute of Integrative Biology
University of Liverpool
Biosciences Building
Liverpool
L69 7ZB
--
Phone:   +44(0)151-795 0349
Email:s.anton...@liverpool.ac.ukmailto:s.anton...@liverpool.ac.uk

[ccp4bb] MS82 Ultimate Resolution and Neutron Crystallography IUCr2014 Montreal

[Antonyuk, Svetlana]

Dear all,

Do you have an exciting high resolution structure you would like to tell us 
about? Then we would like to encourage you to apply for a 20 min oral 
presentation at the M82 session on Ultimate Resolution and Neutron 
Crystallography at IUCR 2014 in Montreal. Please do so as soon as possible.

 
http://iucr2014.org/side_call_for_abstracts/instructions_for_abstract_submission/instructions_for_abstract_submission_e.shtml


Looking forward for your applications,

Matthew Blakeley  Svetlana Antonyuk

Dr. Svetlana Antonyuk
Senior Lecturer
Institute of Integrative Biology
University of Liverpool
Biosciences Building
Liverpool
L69 7ZB
--
Phone:   +44(0)151-795 0349
Email:s.anton...@liverpool.ac.ukmailto:s.anton...@liverpool.ac.uk

[ccp4bb] Postdoctoral position in Structural Biology ( University of Liverpool, UK)

[Antonyuk, Svetlana]

PDRA Structural Biology of Membrane and Soluble Proteins and their complexes
Salary: £ 31644 pa plus pension

You will join the Molecular Biophysics Group 
(www.biophysics.liv.ac.ukhttp://www.biophysics.liv.ac.uk) to work on a 
BBSRC-supported project on structure-function-mechanism studies of Cu-nitrite 
reductase and membrane bound nitric oxide reductase and the role of metabolon 
complex formation in controlling levels of cytotoxic NO.  The project will link 
crystallographic studies with techniques to probe factors that control delivery 
of electrons and protons to the active site of these enzymes. You will be 
responsible for using established molecular biology procedures underpinning the 
overexpression and purification of a number of enzymes and their mutants 
including membrane proteins and undertake crystallographic, spectroscopic and 
mechanistic aspects of the programme. You will spend two periods of up to 4 
weeks in the RIKEN laboratories in Japan as part of a collaborative programme 
alongside two PhD students working on membrane-bound nitric oxide reductases.

You should have a PhD in a relevant area preferably with experience in protein 
crystallography and practical knowledge of molecular biology and membrane 
protein purification. The post is available for up to 4 years but the initial 
appointment will be made for 3 years. Excellent verbal and written 
communication skills are required.
-

Informal enquiries to
Professor S Hasnain, Max Perutz Professor of Molecular Biophysics on 0151 795 
5149,
email: s.s.hasn...@liv.ac.ukmailto:s.s.hasn...@liv.ac.uk

or  Dr S Antonyuk



Dr. Svetlana Antonyuk
Institute of Integrative Biology
University of Liverpool
Biosciences Building
Liverpool
L69 7ZB
--
Phone:   +44(0)151-795 0349
Email:s.anton...@liverpool.ac.ukmailto:s.anton...@liverpool.ac.uk

[ccp4bb] Biophysics and Synthetic Biology Symposium, 18th December 2013

[Antonyuk, Svetlana]

Biophysics and Synthetic Biology Symposium

Life Sciences Building, Lecture Theatre 2, University of Liverpool

18th December 2013


The Biophysics and Synthetic Biology Symposium will take place in celebration 
of the successful career of Professor Robert Eady and his 10th year with the 
Molecular Biophysics Group 
(www.biophysics.liv.ac.ukhttp://www.biophysics.liv.ac.uk).


http://www.liv.ac.uk/integrative-biology/news/stories/title,375896,en.htm

Registration is free - please email 
louise.cromp...@liv.ac.ukmailto:louise.cromp...@liv.ac.uk by 5th of December 
2013.


Dr. Svetlana Antonyuk
Lecturer
Institute of Integrative Biology
University of Liverpool
Biosciences Building
Liverpool
L69 7ZB
--
Phone:   +44(0)151-795 0349
Email:s.anton...@liverpool.ac.ukmailto:s.anton...@liverpool.ac.uk

[ccp4bb] FW: 21st July 2011 Barkla Blundell Celebratory Symposium

[Antonyuk, Svetlana]

IMPORTANT: Registration is free but participation requires registration by
sending an email to Mrs Angela Dell, d...@liverpool.ac.uk.




barkla_blundell_symposium_21July.pdf
Description: barkla_blundell_symposium_21July.pdf