[ccp4bb] coot
Hello everybody, Currently I am refining my 6 x 220 amino acid structure and I was wondering if COOT is automatically writing a kind of protocol what I am changing in my pdb file when I am fitting-in new residues or mutate amino acids. If so where can I find it? Thanks a lot, Stefanie Dr. Stefanie Freitag-Pohl Durham University Chemistry Dept South Road Durham. DH1 3LE Tel: 0191 3342143 Email: stefanie.freitag-p...@durham.ac.uk
[ccp4bb] crystal contacts and ligand binding
Dear all, I am wondering if there are publications, where it is shown that a ligand/substrate was not able to bind in one crystal form of a protein, but was found in another crystal form. In other words: is there a case where the crystal packing interactions are proofed to be responsible for non-binding of a substrate? Thanks for any hints, Stefanie Dr. Stefanie Freitag-Pohl Durham University Chemistry Dept South Road Durham. DH1 3LE Tel: 0191 3342143 Email: stefanie.freitag-p...@durham.ac.uk
