You can run a few µl of your sample on a native gel or agarose gel and 
visualise co-purified DNA by ethidium bromide/gel red staining.

If your protein is stable at high salt concentrations (and a lot of DNA-binding 
proteins are) you can use a high salt concentration (like 1 M) in the lysis 
buffer.

Ion exchange is also a good way to get rid of DNA, in my experience.

Lisa 

Reply via email to