[ccp4bb] vacancy for structural biology research technician/assoc. at Diamond/Research Complex at Harwell **deadline 27th August*** interviews 11th Sept

2017-08-11 Thread Martin Walsh 
Dear all we have a vacancy for a structural biology research tech/assoc – great 
opportunity to be embedded in research work at diamond/research complex

Hot tip for UK based people interested …get your applications in before you go 
off and enjoy your bank holiday weekend!interviews scheduled for 11th  
September.

Details in link below:

http://www.diamond.ac.uk/Careers/Vacancies/All/089_17_CH.html

Martin

--
Martin A. Walsh,
Diamond Light Source Ltd
Diamond House,
Harwell Science & Innovation Campus
Didcot OX11 0DE
UK
T:+44 1235 778518
E: martin.wa...@diamond.ac.uk


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[ccp4bb] reminder that closing date for CryoEM sample preparation workshop is ***THIS SUNDAY 6th AUGUST***

2017-08-04 Thread Martin Walsh 
Dear all just a reminder that our 2nd workshop aimed at newcomers to CryoEM for 
preparation and initial characterization of samples for single particle CryoEM 
experiments has a deadline for applicants of this Sunday the 6th August!!! 
…link below

http://www.diamond.ac.uk/Home/Events/2017/cryoEM-Worskhop-October-2017.html

the workshop will provide near one-to-one tuition and hands-on preparation of 
cryoem sample grids taking full advantage of the convocation of titan krios’s 
at eBIC ( http://www.diamond.ac.uk/Science/Integrated-facilities/eBIC.html )

Martin




--
Martin A. Walsh,
Diamond Light Source Ltd
Diamond House,
Harwell Science & Innovation Campus
Didcot OX11 0DE
UK
T:+44 1235 778518
E: martin.wa...@diamond.ac.uk


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[ccp4bb] eBIC centre coordinator vacancy

2017-07-21 Thread Martin Walsh 
Dear all, reminder that we have a vacancy at eBIC for a centre coordinator

Full details here:
http://www.diamond.ac.uk/Careers/Vacancies/All/061-17-CH.html

Please do contact Peijun Zhang for informal discussions

Best,
Martin


--
Martin A. Walsh,
Diamond Light Source Ltd
Diamond House,
Harwell Science & Innovation Campus
Didcot OX11 0DE
UK
T:+44 1235 778518
E: martin.wa...@diamond.ac.uk


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Innovation Campus, Didcot, Oxfordshire, OX11 0DE, United Kingdom

[ccp4bb] 2nd CryoEM sample preparation Workshop 2-4th Oct 2017 @ DLS - deadline for applications 6th august

2017-07-13 Thread Martin Walsh 
Dear all we are pleased to announce a 2nd workshop aimed at newcomers to CryoEM 
for prepration and initial characterization of samples for single particle 
CryoEM experiments– full details in link below

http://www.diamond.ac.uk/Home/Events/2017/cryoEM-Worskhop-October-2017.html

the workshop will provide near one-to-one tuition and hands-on preparation of 
cryoem sample grids taking full advantage of the convocation of titan krios’s 
at eBIC ( http://www.diamond.ac.uk/Science/Integrated-facilities/eBIC.html )

Martin


--
Martin A. Walsh,
Diamond Light Source Ltd
Diamond House,
Harwell Science & Innovation Campus
Didcot OX11 0DE
UK
T:+44 1235 778518
E: martin.wa...@diamond.ac.uk


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Diamond Light Source Limited (company no. 4375679). Registered in England and 
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Innovation Campus, Didcot, Oxfordshire, OX11 0DE, United Kingdom

[ccp4bb] 2nd CryoEM sample preparation Workshop 2-4th Oct 2017 @ DLS - deadline for applications 6th august

2017-07-13 Thread Martin Walsh 
Dear all we are pleased to announce a 2nd workshop aimed at newcomers to CryoEM 
for prepration and initial characterization of samples for single particle 
CryoEM experiments– full details in link below

http://www.diamond.ac.uk/Home/Events/2017/cryoEM-Worskhop-October-2017.html

the workshop will provide near one-to-one tuition and hands-on preparation of 
cryoem sample grids taking full advantage of the convocation of titan krios’s 
at eBIC ( http://www.diamond.ac.uk/Science/Integrated-facilities/eBIC.html )

Martin

--
Martin A. Walsh,
Diamond Light Source Ltd
Diamond House,
Harwell Science & Innovation Campus
Didcot OX11 0DE
UK
T:+44 1235 778518
E: martin.wa...@diamond.ac.uk


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Innovation Campus, Didcot, Oxfordshire, OX11 0DE, United Kingdom

[ccp4bb] Deadline for rapid access proposals at eBIC@Diamond

2016-12-21 Thread Martin Walsh 
Dear all – we are extending the 1st January 2017 deadline for rapid access 
proposals at eBIC to the 8th January 2017 
(http://www.diamond.ac.uk/Science/Integrated-facilities/eBIC/How-to-apply.html)

Happy christmas

Martin

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[ccp4bb] Deadline for applications to attend CryoEM sample preparation workshop - ***25th November 2016***

2016-11-22 Thread Martin Walsh 
Dear all the deadline for applications to be one of 12 students on our 
inaugural Cryo-EM sample handling workshop is fast approaching to help us 
avoid a server meltdown please do get your application in before the last hour 
of Friday 25th November!!

Full details from link below:

http://www.diamond.ac.uk/Home/Events/2017/EM-Workshop-2017.html

Martin


Martin A. Walsh
Diamond Light Source Ltd.,
Harwell Science & Innovation Campus,
Didcot OX11 0DE
UK
t: +44-1235-778518
f: +44-1235-778448
e: martin.wa...@diamond.ac.uk


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may sustain as a result of software viruses which may be transmitted in or with 
the message.
Diamond Light Source Limited (company no. 4375679). Registered in England and 
Wales with its registered office at Diamond House, Harwell Science and 
Innovation Campus, Didcot, Oxfordshire, OX11 0DE, United Kingdom

[ccp4bb] practical workshop on sample preparation for Cryo-EM - application deadline 25th November - 12 places available for EU based scientists

2016-10-28 Thread Martin Walsh 
Dear all

We are pleased to announce a practical workshop for preparation of samples for 
Cryo-EM which will run from the 9th to 11th January 2017 at eBIC @ Diamond 
light source. The course is funded by eBIC and the Horizon 2020 project iNEXT 
(http://www.inext-eu.org ) with the support of FEI.

There are a total of 12 places available to EU based scientists.  Full details 
and how to apply …please see the workshop website : 
http://www.diamond.ac.uk/Home/Events/2017/EM-Workshop-2017.html

Deadline for receipt of applications is 25th November and the successful 
applicants will be notified by the 1st December 2016.


Confirmed Speakers:
•Bettina Böttcher, Hans Knoll Institute, Germany
•Sarah Butcher, Biocenter, Finland
•Felix DeHaas, FEI, Eindhoven
•Venkat Dandey, New York Structural Biology Center, USA
•Christoph Diebolder, NeCEN, Leiden University
•Deryck Mills, Max-Planck Institute, Frankfurt, Germany
•Peter Peters, Maastricht University, Netherlands
•Chris Russo, MRC Laboratory, UK
•Sonja Welsch, FEI, Eindhoven

Summary of Schedule:
Day One (January 9th)
Morning: Lectures (General Intro to cryoEM and Sample Preparation)
Afternoon: Hands on sample preparation sessions

Day two (January 10th):
Morning: Lectures (High Throughput and Technological Advances)
Afternoon: Hands on sessions (Vitrobots and Microscope time)

Day three (January 11th)
Morning: Lectures (Tomography/FIB-SEM/correlative light and EM)
Afternoon: Hands on sessions (Microscope time) followed by student presentations


All the best,

Martin



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Innovation Campus, Didcot, Oxfordshire, OX11 0DE, United Kingdom

[ccp4bb] Postdoc position in structural biology of a novel bifunctional bacterial transporter at Diamond/RCaH -closing date for applications 15th March

2015-02-26 Thread Martin Walsh 
Dear All
 We have a vacancy for an enthusiastic postdoctoral researcher to join our 
group within the Research Complex at Harwell to investigate the structure and 
function of a novel bacterial integral membrane complex involved in innate 
immune evasion using primarily single particle electron cryo microscopy in 
combination with X-ray crystallography.

Full details and how to apply can be found here: 
http://www.diamond.ac.uk/Careers/Vacancies/All/DIA1004-CH.html

IF you have informal enquires don’t hesitate to contact me by email

Martin
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may sustain as a result of software viruses which may be transmitted in or with 
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Diamond Light Source Limited (company no. 4375679). Registered in England and 
Wales with its registered office at Diamond House, Harwell Science and 
Innovation Campus, Didcot, Oxfordshire, OX11 0DE, United Kingdom

[ccp4bb] principle beamline scientist for SAXS/BioSAXS beamline at Diamond -Closingdate 6th October 2013

2013-09-11 Thread Martin Walsh 
Dear all B21 is a tuneable bending magnet beamline dedicated to small angle 
X-ray scattering (SAXS) which will come online in 2014 at Diamond. There is now 
an exciting opportunity to take the scientific and operation lead of the 
beamline. As there is an increased need for SAXS in the biological sciences and 
the beamline aims to deliver an automated facility for BioSAXS experiments, 
this opportunity may be of strong interest to readers of this BB

Full details and how to apply can be found here:
http://www.diamond.ac.uk/Home/Jobs/Current/DIA0870_SB.html

Don't hesitate to contact me directly for informal discussions
thanks
Martin


Martin A. Walsh
Diamond Light Source Ltd.,
Harwell Science  Innovation Campus,
Didcot OX11 0DE
UK
t: +44-1235-778518
f: +44-1235-778448
e: martin.wa...@diamond.ac.uk




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retain, distribute or disclose the information in or attached to the e-mail.

Any opinions expressed within this e-mail are those of the individual and not 
necessarily of Diamond Light Source Ltd. 

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are free from viruses and we cannot accept liability for any damage which you 
may sustain as a result of software viruses which may be transmitted in or with 
the message.

Diamond Light Source Limited (company no. 4375679). Registered in England and 
Wales with its registered office at Diamond House, Harwell Science and 
Innovation Campus, Didcot, Oxfordshire, OX11 0DE, United Kingdom

[ccp4bb] Principal Beamline scientist for the Microfocus beamline I24 at Diamond - available - closing date 18/8/2013

2013-07-29 Thread Martin Walsh 
Dear all there is an exciting opportunity at Diamond to take the lead role in 
running and developing beamline I24. The closing date for applications is the 
18th August. A summary of the post can be found here:

http://www.diamond.ac.uk/Home/Jobs/Current/DIA0855_SB.html

informal inquiries can be directed directly to myself

Martin





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may sustain as a result of software viruses which may be transmitted in or with 
the message.

Diamond Light Source Limited (company no. 4375679). Registered in England and 
Wales with its registered office at Diamond House, Harwell Science and 
Innovation Campus, Didcot, Oxfordshire, OX11 0DE, United Kingdom

[ccp4bb] Software scientist/engineer in the MX Data acquisition group at Diamond -CLOSING DATE 30th June 2013

2013-06-13 Thread Martin Walsh 
Dear all there is an opening within the MX data acquisition group at Diamond 
for a software scientist/engineer with experience in Java programming and also 
python. The post will form part of the team contributing to Diamond's MX 
beamline GUI software developments and methods/tools for users

Full details of the post  can be found in the following link

http://www.diamond.ac.uk/Home/Jobs/Current/DIA0825_LH.html

Please pass this on to anyone you think would be interested !

Thanks
Martin




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may sustain as a result of software viruses which may be transmitted in or with 
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Diamond Light Source Limited (company no. 4375679). Registered in England and 
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Innovation Campus, Didcot, Oxfordshire, OX11 0DE, United Kingdom

[ccp4bb] Workshop focused on exploitation of Synchrotron Radiation Circular Dichroism for Membrane Protein and Carbohydrate Research - 31 May 2013, Leeds

2013-04-26 Thread Martin Walsh 
Dear all, those of you working in the membrane protein and/or carbohydrate 
field may be very interested in attending a 1 day workshop which will highlight 
the unique capabilities of the CD beamline B23, at Diamond. The workshop is 
focused  on how the technique can aid your research in these key areas.

The workshop will be a dynamic mix of introducing beamline basics, how to get 
beamtime, sample requirements   experimental possibilities as well as a series 
of science case studies from recent users of the beamline and ample time for 
discussions with both beamline staff and experienced users.

There is a limited number of places so register now to avoid disappointment!

Full  details and registration for the workshop are available from the this 
link:

Diamond B23 circular dichroism beamline Workshop Series / University of Leeds / 
University of 
Liverpoolhttp://www.diamond.ac.uk/Home/Events/B23-Workshop-Series.html
B23 Roadshow Series - Membrane Protein and Carbohydrate Research Workshop
Friday 31 May 2013, The Metropole Hotel, Leeds
Hosted by: Diamond Light Source, University of Leeds and University of Liverpool
On the 31th May 2013, Diamond Light Source (DLS), together with the University 
of Leeds and University of Liverpool will hold a one-day workshop dedicated to 
membrane protein and carbohydrate research, with a particular view to promote 
the synchrotron based CD beamline B23 for these biological materials.
The event will be held at The Metropole 
Hotelhttp://www.metropole-hotel.co.uk/, Leeds, a convenient location well 
accessible using public transport. The workshop is free to attend and includes 
refreshments and lunch, but registration is limited to 50 places. Successful 
registrants will be expected to reconfirm their place nearer the time in order 
to give those on a reserved list a chance to take up any cancellation places.
Confirmed speakers
Simon Patching, Leeds University
Konstantinos Beis, Imperial College London
Bonnie Wallace, Birkbeck College
Marcelo Lima, Federal University of Sao Paolo
David Middleton, Liverpool University
Paul Walton, York University
Alex Cameron, Warwick University
Giuliano Siligardi  Rohanah Hussain, Diamond Light Source B23
For details on the workshop and to register, please visit the 
websitehttp://www.diamond.ac.uk/Home/Events/B23-Workshop-Series.html.
This will be the second event in a series of Road shows to highlight Diamond 
Light Source B23 throughout the country. The next event is scheduled to take 
place in Liverpool on the 1st November 2013 on the topic of Material Science. 
If you are interested in participating in future events please email Rohanah 
Hussainmailto:rohanah.huss...@diamond.ac.uk.
With best wishes,
Rohanah Hussain, Giuliano  Siligardi, Peter Henderson and Edwin Yates.

[ccp4bb] Diamond App for MX

2013-01-24 Thread Martin Walsh 
Dear All



(apologies for using the bb mailing list for something so specific but we 
thought it was the best way to get the details to probably all our users)

Diamond would like to announce V1.0 of SynchLink, an iPhone/iPad (iOS v6 
onwards) app which allows users of Diamond MX beamlines to 
monitor/re-visit/search information on their data collections and automated 
data processing results recorded in ISPyB (you will need a fedid login). The 
app can also be used to check beamline and synchrotron ring status.



We encourage you to try it and give feedback - if people find it useful we plan 
to develop it further and make it available on other platforms.

The app is available from the App Store and is free.

Please report problems/feedback/suggestions to scisoftj...@diamond.ac.uk



The app was developed by Helen Ginn, a very talented Oxford Biochemistry 
undergraduate during a summer internship. Helen was supervised by Dave Stuart 
at Oxford and Martin Walsh/Alun Ashton at Diamond. There was also expert input 
from Ghita Kouadri Mostefaoui and Karl Levik at Diamond who developed the 
WebServices and integration to ISPyB.



Yours



Dave and Martin






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Re: [ccp4bb] Crystallography on BBC Radio 4 next week

2012-11-22 Thread Martin Walsh 
Martyn, your selling in our time short...I'd say it's always b*$($ brilliant! 
-interesting to see who his guests will be next week to discuss the history of 
crystallography.
Bragg is the chancellor of Leeds university so it all fits rather well!
M


-Original Message-
From: CCP4 bulletin board [mailto:CCP4BB@JISCMAIL.AC.UK] On Behalf Of Martyn 
Winn
Sent: 22 November 2012 14:13
To: ccp4bb
Subject: Re: [ccp4bb] Crystallography on BBC Radio 4 next week

I'd just like to comment that In Our Time is usually pretty good. I caught the 
end of this morning's program on the Borgias. After hearing about murder, 
nepotism and incest, it was a bit disorientating to hear Melvyn announce 
crystallography as the next subject :)

m

 -Original Message-
 From: CCP4 bulletin board [mailto:CCP4BB@JISCMAIL.AC.UK] On Behalf Of 
 Peter Keller
 Sent: 22 November 2012 13:52
 To: ccp4bb
 Subject: Re: [ccp4bb] Crystallography on BBC Radio 4 next week
 
 Dear all,
 
 I have had several queries about this off-list, so here are some 
 clarifications.
 
 I don't know if Melvyn Bragg is related to WL and WH Bragg. I doubt 
 it, but if he is maybe he will say. (Bragg is a fairly common name in
 English.)
 
 The normal subject matter of In Our Time is humanities-based (i.e.
 art, history, philosophy etc.), but they deal with scientific or 
 mathematical subjects occasionally.
 
 There are two live broadcasts, at 09:00 and 21:30 UK time. The later 
 one is a shortened version (edited from about 42 mins to about 28), so 
 better to listen to the earlier one if you can.
 
 There are three options for listening other than the terrestrial radio 
 broadcast. All should work outside the UK (restrictions on using the 
 BBC iPlayer overseas mostly apply only to television, or on the radio 
 to certain special broadcasts such as some sporting events).
 
 (i) Live on the internet at the times above: go to the programme page 
 at http://www.bbc.co.uk/programmes/b01p0s9s and click on the 
 LISTEN
 icon (with a picture of a small loudspeaker) towards the upper right 
 of the page.
 
 (ii) Using iPlayer after the second broadcast has finished. Go to the 
 programme page at http://www.bbc.co.uk/programmes/b01p0s9s and click 
 on the Listen now button on the left of the picture illustrating the 
 programme. In principle this should become available within a few 
 minutes of the end of the second broadcast (i.e. soon after 22:00 UK 
 time), but sometimes there is a longer delay of up to an hour. It 
 won't expire, so you can always listen on another day.
 
 (iii) Download a podcast in mp3 format from 
 http://www.bbc.co.uk/podcasts/series/iot. This will become available 
 sometime after the second broadcast has finished, but it could be a 
 day or two afterwards. These podcasts also don't expire or disappear: 
 you can download them years after the original broadcasts.
 
 Options (ii) and (iii) will get you the full rather than the shortened 
 version of the programme.
 
 Regards,
 Peter.
 
 On Thu, 2012-11-22 at 10:30 +, Peter Keller wrote:
  Dear all,
 
  On Thursday next week, the BBC radio program In Our Time will be 
  discussing the history of crystallography. The link to the program 
  is http://www.bbc.co.uk/programmes/b01p0s9s. Unfortunately, it 
  doesn't
 say
  who the guests are, but they usually manage to find people with
 something
  interesting to say, even if the presenter Melvyn Bragg's grasp of
 scientific
  material isn't always that great.
 
  I think that from outside the UK it is possible to listen live from
 the link
  above, and that a day or two after the broadcast a podcast will be
 available
  to download from http://www.bbc.co.uk/podcasts/series/iot.
 
  Regards,
  Peter.
 
 
 --
 Peter Keller Tel.: +44 (0)1223
 353033
 Global Phasing Ltd., Fax.: +44 (0)1223
 366889
 Sheraton House,
 Castle Park,
 Cambridge CB3 0AX
 United Kingdom

[ccp4bb] Post-Doc position at Diamond Light source

2012-10-01 Thread Martin Walsh 
Dear all - this is a reminder for the Postdoc post detailed below - closing 
date is THIS FRIDAY
- don't hesitate to contact me directly for more information. Application 
details can be found on the Diamond web pages 
(http://www.diamond.ac.uk/Home/Jobs/Current/DIA0766_TH.html)
Martin
===
Post-Doctoral Research Associate - Macromolecular Crystallography
Job Reference

DIA0766/TH

Post Type

Full time / 3 year fixed term

Division

Science

Salary information

£28,409 - £35,629; starting salary, dependent on assessment of previous 
relevant experience and qualifications

Application deadline

5th October 2012


Date interviews


19th OCTOBER 2012


Duties
Diamond Light Source is the UK's national synchrotron science facility. Located 
at Harwell Science  Innovation Campus in Oxfordshire, we enable world-leading 
research across a wide range of scientific disciplines and industrial 
applications..
We are looking for a highly motivated and experienced structural biologist at 
the Post Doctoral Research Associate level to join a multidisciplinary 
collaboration formed by groups located at the central laser facility within the 
Research complex at Harwell, Diamond and the Universities of Strathcylde and 
Nottingham. The post will be based within the group of Martin Walsh at Diamond.

The aim of the project is to combine X-ray crystallography, time resolved 2D-IR 
spectroscopy and biochemical techniques to study the structure and function of 
targeted bacterial sensors of nitric oxide.

The project will involve elements of biochemistry, structural biology and 
infrared spectroscopy, including time resolved and multidimensional methods. 
Expertise in all areas is not required, though a strong background in cloning 
and overproduction of proteins for structural studies is advantageous. The 
successful candidate will join ongoing collaborative projects in place between 
Strathclyde, Diamond, Nottingham and the Research Complex at Harwell  that aim 
to investigate the mechanisms of protein systems from a multidisciplinary 
perspective. Regular interactions with Strathclyde and the Research Complex are 
envisaged. As such the project will suit an ambitious and motivated candidate 
with a strong commitment to multidisciplinary research.


Qualifications and Experience: Essential

  *   PhD in biochemistry or related disciplines; or equivalent qualification 
or experience;
  *   Experience in cloning and recombinant expression of proteins for 
structural studies
  *   Sound understanding of methods, systems and approaches relating to 
macromolecular crystallography;
  *   Good laboratory research skills;
  *   Good interpersonal, communication and presentational skills;
  *   Good problem solving skills;
  *   Ability to plan and carry out a research project;
  *   Ability to interact effectively with staff at all levels;
  *   Ability to work on own initiative and take personal responsibility for 
delivery of work;
  *   Must be available to travel occasionally within the UK and abroad, 
including overnight absences.
Qualifications and Experience: Desirable

  *   Expertise in single crystal protein structure solution
  *   Experience or knowledge of synchrotrons and diffraction experiments;
Further Information

  *   Candidates are encouraged to contact Dr. Martin Walsh 
(martin.wa...@diamond.ac.ukmailto:martin.wa...@diamond.ac.uk) for further 
details on the responsibilities and research associated with the post.
Applying for employment
For further details on applying for employment at Diamond, please visit our 
'Application Form'http://www.diamond.ac.uk/Home/Jobs/Apply/Form.html page.






-- 

This e-mail and any attachments may contain confidential, copyright and or 
privileged material, and are for the use of the intended addressee only. If you 
are not the intended addressee or an authorised recipient of the addressee 
please notify us of receipt by returning the e-mail and do not use, copy, 
retain, distribute or disclose the information in or attached to the e-mail.

Any opinions expressed within this e-mail are those of the individual and not 
necessarily of Diamond Light Source Ltd. 

Diamond Light Source Ltd. cannot guarantee that this e-mail or any attachments 
are free from viruses and we cannot accept liability for any damage which you 
may sustain as a result of software viruses which may be transmitted in or with 
the message.

Diamond Light Source Limited (company no. 4375679). Registered in England and 
Wales with its registered office at Diamond House, Harwell Science and 
Innovation Campus, Didcot, Oxfordshire, OX11 0DE, United Kingdom

[ccp4bb] Post-Doc position at Diamond Light Source

2012-09-10 Thread Martin Walsh 
Dear all - see below for a postdoc position available immediately at Diamond - 
don't hesitate to contact me directly for more information. Application details 
can be found on the Diamond web pages 
(http://www.diamond.ac.uk/Home/Jobs/Current/DIA0766_TH.html)
Martin
===
Post-Doctoral Research Associate - Macromolecular Crystallography
Job Reference

DIA0766/TH

Post Type

Full time / 3 year fixed term

Division

Science

Salary information

£28,409 - £35,629; starting salary, dependent on assessment of previous 
relevant experience and qualifications

Application deadline

5th October 2012

Date of interviews

TBC


Duties
Diamond Light Source is the UK's national synchrotron science facility. Located 
at Harwell Science  Innovation Campus in Oxfordshire, we enable world-leading 
research across a wide range of scientific disciplines and industrial 
applications..
We are looking for a highly motivated and experienced structural biologist at 
the Post Doctoral Research Associate level to join a multidisciplinary 
collaboration formed by groups located at the central laser facility within the 
Research complex at Harwell, Diamond and the Universities of Strathcylde and 
Nottingham. The post will be based within the group of Martin Walsh at Diamond.

The aim of the project is to combine X-ray crystallography, time resolved 2D-IR 
spectroscopy and biochemical techniques to study the structure and function of 
targeted bacterial sensors of nitric oxide.

The project will involve elements of biochemistry, structural biology and 
infrared spectroscopy, including time resolved and multidimensional methods. 
Expertise in all areas is not required, though a strong background in cloning 
and overproduction of proteins for structural studies is advantageous. The 
successful candidate will join ongoing collaborative projects in place between 
Strathclyde, Diamond, Nottingham and the Research Complex at Harwell  that aim 
to investigate the mechanisms of protein systems from a multidisciplinary 
perspective. Regular interactions with Strathclyde and the Research Complex are 
envisaged. As such the project will suit an ambitious and motivated candidate 
with a strong commitment to multidisciplinary research.
Qualifications and Experience: Essential

  *   PhD in biochemistry or related disciplines; or equivalent qualification 
or experience;
  *   Experience in cloning and recombinant expression of proteins for 
structural studies
  *   Sound understanding of methods, systems and approaches relating to 
macromolecular crystallography;
  *   Good laboratory research skills;
  *   Good interpersonal, communication and presentational skills;
  *   Good problem solving skills;
  *   Ability to plan and carry out a research project;
  *   Ability to interact effectively with staff at all levels;
  *   Ability to work on own initiative and take personal responsibility for 
delivery of work;
  *   Must be available to travel occasionally within the UK and abroad, 
including overnight absences.
Qualifications and Experience: Desirable

  *   Expertise in single crystal protein structure solution
  *   Experience or knowledge of synchrotrons and diffraction experiments;
Further Information

  *   Candidates are encouraged to contact Dr. Martin Walsh 
(martin.wa...@diamond.ac.ukmailto:martin.wa...@diamond.ac.uk) for further 
details on the responsibilities and research associated with the post.
Applying for employment
For further details on applying for employment at Diamond, please visit our 
'Application Form'http://www.diamond.ac.uk/Home/Jobs/Apply/Form.html page.





-- 

This e-mail and any attachments may contain confidential, copyright and or 
privileged material, and are for the use of the intended addressee only. If you 
are not the intended addressee or an authorised recipient of the addressee 
please notify us of receipt by returning the e-mail and do not use, copy, 
retain, distribute or disclose the information in or attached to the e-mail.

Any opinions expressed within this e-mail are those of the individual and not 
necessarily of Diamond Light Source Ltd. 

Diamond Light Source Ltd. cannot guarantee that this e-mail or any attachments 
are free from viruses and we cannot accept liability for any damage which you 
may sustain as a result of software viruses which may be transmitted in or with 
the message.

Diamond Light Source Limited (company no. 4375679). Registered in England and 
Wales with its registered office at Diamond House, Harwell Science and 
Innovation Campus, Didcot, Oxfordshire, OX11 0DE, United Kingdom

[ccp4bb] vacancy for Java Web Application Developer at Diamond

2012-06-12 Thread Martin Walsh 
Dear all, this new vacancy at Diamond may be of interest for some readers of 
this BB which is focused on further development of ISPyB at Diamond. Full 
details of the post can be found here:

http://www.diamond.ac.uk/Home/Jobs/Current/DIA0737_TH.html

Informal inquiries can be made to myself (martin.wa...@diamond.ac.uk ) or Alun 
Ashton (alun.ash...@diamond.ac.ukmailto:alun.ash...@diamond.ac.uk)

Thanks
Martin

[ccp4bb] Crystallographer - Principal Beamline Scientist (I04-1) position available at DIAMOND

2012-05-02 Thread Martin Walsh 
Dear all,
We are in the process of recruiting a Senior Scientist at Diamond with 
responsibility for the MX beamline I04-1 which forms part of the MX village 
suite.
This provides an exciting opportunity to lead the operation and development of 
I04-1 through the direct management of a small team of scientists and 
interactions with the other four currently operational beamlines within the MX 
village at Diamond (http://www.diamond.ac.uk/Home/Beamlines/MX.html).

The Principal Beamline Scientist is expected to establish an internationally 
competitive research programme that complements the activities of the MX 
village (Structural biology, Crystallographic methods development and/or 
Instrumentation). To this end Diamond provides state of the art facilities for 
all aspects of structural biology and will fund a full time post-doctoral 
research associate, as well as supporting graduate students through sponsorship 
with academic institutions via the Diamond PhD studentship programme.

Full details of the post and how to apply can be found here:
http://www.diamond.ac.uk/Home/Jobs/Current/DIA0732_TH.html

Informal inquires about the post can be directed directly to Martin Walsh 
either by telephone (+44 (0) 1235 778518) or via email: 
martin.wa...@diamond.ac.ukmailto:martin.wa...@diamond.ac.uk

The closing date is set at 2/6/2012
Martin

Re: [ccp4bb] Collecting small-molecule diffraction on a Macromolecular xtallography beam line

2012-02-08 Thread Martin Walsh 
Hi Giorgio, there are beamlines dedicated to small molecule crystallography at 
synchrotrons as well. I can suggest I19 at Diamond (obviously) but there are 
others!

http://www.diamond.ac.uk/Home/Beamlines/I19.html

Martin


-Original Message-
From: CCP4 bulletin board [mailto:CCP4BB@JISCMAIL.AC.UK] On Behalf Of Giorgio 
Giardina
Sent: 08 February 2012 11:42
To: ccp4bb
Subject: [ccp4bb] Collecting small-molecule diffraction on a Macromolecular 
xtallography beam line

Hello,
I have some interesting small molecule xtals.
I was wondering if it is possible to collect a small molecule data-set using a 
sincrotron macromolecular  xtallography beam line, maybe with a very low beam 
intensity and moving the detector as close as possible?
Has anybody experienced that?
And if I get the images back home,  can I process them using standard 
macromolecular software or do I need ab-initio special programs?
Will MR work for phasing?

Thanks in advance,
Giorgio

[ccp4bb] Reminder for Post-doc vacancy at Diamond -closing date 22-sept-11

2011-09-13 Thread Martin Walsh 
Dear all just a reminder as this was posted during holiday period...we have a 
vacancy for a 1 year post-doc at diamond which brings together crystallography, 
2D-IR spectroscopy and biology. Full details in link below:

http://www.mis.strath.ac.uk/Personnel/open/r702011.htm

informal discussions can be directed to me at martin.wa...@diamond.ac.uk or 
t:01235 778518

thanks
Martin

[ccp4bb] Immediate opeining for a Post-DOC fellowship based at Diamond the Research Complex at Harwell

2011-08-24 Thread Martin Walsh 
--
RESEARCH ASSOCIATE: A Multidisciplinary Approach to Protein Function and 
Exploitation
--

Department of Physics/Strathclyde Institute of Pharmacy and Biomedical Sciences

DIAMOND LIGHT SOURCE

FIXED TERM (1 yr)

Salary £29,099-£35,788

===

Applications are invited for this joint post between the 
Department of Physics and the Strathclyde Institute of Pharmacy and Biomedical 
Sciences at the University of Strathclyde, and Diamond Light Source Ltd (the UK 
national synchrotron science facility situated at Harwell in Oxfordshire).  The 
post holder will be based at Diamond, with work being directed by Dr's Neil 
Hunt, Nicholas Tucker, Paul Hoskisson at Strathclyde and Martin Walsh at 
Diamond.

The appointment is initially for one year. The aim of the 
project is to combine X-ray crystallography, time resolved 2D-IR spectroscopy 
and biochemical techniques to study the structure and function of the E coli 
Hmp NO dioxygenase enzyme system and to work towards integration of ultrafast 
spectroscopy with the Diamond MX beamlines for future exploitation in 
biological research. The project will involve elements of biochemistry, 
structural biology and infrared spectroscopy, including time resolved and 
multidimensional methods. Expertise in all areas is not required though a 
strong background in structural biology, protein biochemistry, biophysics, 
infrared spectroscopy or time resolved/ultrafast spectroscopy would be 
advantageous. 

The successful candidate will join ongoing collaborative 
projects in place between Strathclyde, DLS and the Research Complex at Harwell 
(http://www.rc-harwell.ac.uk) that aim to investigate the mechanisms of protein 
systems from a multidisciplinary perspective. Regular interactions with 
Strathclyde and the Research Complex are envisaged. As such the project will 
suit an ambitious and motivated candidate with a strong commitment to 
multidisciplinary research.

For informal enquiries please contact 
martin.wa...@diamond.ac.uk, neil.h...@strath.ac.uk, nick.tuc...@strath.ac.uk or 
paul.hoskis...@strath.ac.uk.


For an application pack visit http://vacancies.strath.ac.uk or contact Human 
Resources, University of Strathclyde, Glasgow G1 1XQ. Tel. 0141 553 4133, 
quoting ref: JA/R70/2011.  

Closing date: 22 September 2011

We value diversity and welcome applications from all sections of the community
The University of Strathclyde is a Registered Scottish Charity, No SCO15263

[ccp4bb] Macromolecular Crystallographer Post in the Industrial Liaison office at Diamond

2011-05-12 Thread Martin Walsh 
Dear All, we have a permanent post available for a Macromolecular 
Crystallographer in the Industrial Liaison Group at Diamond. Full details and 
how to apply can be found at

http://www.diamond.ac.uk/Home/Jobs/Current/DIA0619-TH.html. (Closing date for 
receipt of applications is the 17th June 2011)

A brief summary of the post is given here:

  
Industrial Liaison Scientist - MX
Circa £32k 
Full-time
Ref: DIA0619/TH
Closing date: 17/6/2011


Diamond Light Source is the UK's national synchrotron science facility. Located 
at Harwell Science  Innovation Campus in Oxfordshire, we enable world-leading 
research across a wide range of scientific disciplines and industrial 
applications

We are seeking a Scientist to join our Industrial Liaison Group to develop and 
deliver the service offered to industrial users of Diamond in the field of 
macromolecular crystallography (MX). You will be involved in the optimisation, 
operation and marketing of the industrial aspects of the MX beamlines. As part 
of a multi disciplinary team you will be working closely with the MX Group and 
ideally you should have experience of working in a commercial environment.

Please direct informal inquiries to Elizabeth Shotton (Elizabeth.shotton at 
diamond.ac.uk)

[ccp4bb] Post doc positions at Diamond

2011-01-10 Thread Martin Walsh 
Dear All, just a new year reminder as application deadlines are
approaching...  

We currently have two post-doc positions available at Diamond, one
associated with beamline I04-1 and the other supported through the
Wellcome Trust.

Full details available in links below:

http://www.diamond.ac.uk/Home/Jobs/Current/DIA0584-TH.html (deadline
12/1/2011, interviews 21/1/2011)

http://www.diamond.ac.uk/Home/Jobs/Current/DIA0587-TH.html (deadline
18/1/2011, interviews 4/2/2011)

Martin

[ccp4bb] Wellcome Trust funded Post-doctoral position at Diamond Light Source

2010-12-13 Thread Martin Walsh 
Wellcome Trust Funded Post-Doctoral Research Post

Job Reference

DIA0587/TH

Post Type

Full time / 3 year fixed term

Division

Science

Salary information

£28,409 - £39,050; starting salary, dependent on assessment of previous 
relevant experience and qualifications

Application deadline

18th January 2011

Date of interviews

4th February 2011

 

Duties

Diamond Light Source is the largest operating medium energy 3rd generation 
source in the world. Located on the Harwell Science and Innovation Campus in 
South Oxfordshire, we host facilities supporting cutting edge research in all 
fields of science.

We are looking for a highly motivated and experienced crystallographer at the 
Post Doctoral Research Associate level to work on a Wellcome trust funded 
project focused on understanding the role of cyclic di-GMP in the regulation of 
bacterial virulence. 

Responsibilities

*   Protein purification, crystallization and structure determination of 
targeted proteins;
*   Publication of results in international peer-reviewed journals;
*   Attend and present work at relevant scientific meetings.

Qualifications and Experience: Essential

*   PhD in biochemistry or related disciplines; or equivalent qualification 
or experience;
*   Sound understanding of methods, systems and approaches relating to 
macromolecular crystallography;
*   Good laboratory research skills;
*   Good interpersonal, communication and presentational skills;
*   Good problem solving skills;
*   Ability to plan and carry out a research project;
*   Ability to interact effectively with staff at all levels;
*   Ability to work on own initiative and take personal responsibility for 
delivery of work;
*   Must be available to travel occasionally within the UK and abroad, 
including overnight absences.

Qualifications and Experience: Desirable

*   Experience or knowledge of synchrotrons;
*   Experience in cloning and recombinant expression of proteins for 
structural studies

Further Information

*   Informal inquiries and further details relating to the post should be 
directed to Dr. Martin Walsh (martin.wa...@diamond.ac.uk 
mailto:martin.wa...@diamond.ac.uk )

Applying for employment
For further details on applying for employment at Diamond, please visit our 
'Application Form' http://www.diamond.ac.uk/Home/Jobs/Apply/Form.html  page. 

Appointments will be made depending on the skills and experience of the 
candidate. Electronic Diamond application forms in MS-Word are preferred. These 
should be emailed to recruitm...@diamond.ac.uk 
mailto:recruitm...@diamond.ac.uk

[ccp4bb] MX Post-Doc postion at Diamond

2010-12-07 Thread Martin Walsh 
Dear all, we have a vacancy for a postdoc within the MX group at Diamond. Full 
details can be found at 
http://www.diamond.ac.uk/Home/Jobs/Current/DIA0584-TH.html. Interested 
candidates can contact me directly by email for further details on research 
project associated with the post

 

Martin

 

PDRA, Beamline I04-1 Diamond

Diamond Light Source is a new synchrotron and a leading scientific facility of 
its type in the world. Located on the Harwell Science and Innovation Campus in 
South Oxfordshire, we host facilities supporting cutting edge research in all 
fields of science.

 

We are looking for a highly motivated and experienced crystallographer at the 
Post Doctoral Research Associate level to join the I04-1 beamline within the 
Macromolecular crystallography village at Diamond. I04-1 is a fixed wavelength 
(0.92 Å) insertion device beamline dedicated to macromolecular crystallography 
(MX) and complements the other four currently operating MX beamlines at 
Diamond. I04-1 provides a high flux X-ray beam for macromolecular structure 
determination by the Single Anomalous Diffraction (SAD) or Molecular 
replacement (MR) methods. A state of the art automated endstation consisting of 
a MD2 microdiffractometer, a Pilatus 2M hybrid pixel array detector and a CATS 
robot for automated sample handling is integrated into a automated data 
reduction pipeline that provides users with a high-throughput crystallography 
platform.

 

Research will be focused on structural studies of a multifunctional bacterial 
uptake system that is required for critical mechanisms of bacterial survival in 
the human.