Dear all, We are looking for two highly motivated, dynamic and driven postdocs to join our cryo-EM muscle structural biology team at the Division of Cell Biology and Imaging, UMass Chan Medical School in Worcester, MA.
The Padron/Craig lab (https://www.umassmed.edu/padron-craig/) has focused on the structure of myosin molecules and muscle thick filaments since discovering the myosin interacting-heads motif (IHM) in filaments by cryo-EM in 2005 (Woodhead et al 2005, Nature 436, 1195-1199 - https://www.nature.com/articles/nature03920), leading to the recently published 4.3 Å resolution structure of the myosin II molecule in the inhibited state (Yang et al. 2020, Nature 588, 521-525 - https://www.nature.com/articles/s41586-020-3007-0 Ideal candidates to join this adventure, solving the near-atomic cryo-EM structure of the IHM in situ, with implications for muscle relaxation and activation, muscle disease, and drug treatment, will possess a broad curiosity and a passion for discovery. Having expertise in cryo-EM/ET or X-ray crystallography will be a plus but is not required, as these positions (NIH-funded for 4-5 years) are an excellent opportunity as well to learn cryo-EM or expand your existing cryo-EM capabilities. Our cryo-EM Core (https://www.umassmed.edu/research/cores/cryo-em-core-facility/) is superbly equipped and staffed to carry out this work (Titan Krios, Talos-Arctica, Glacios, with K3 cameras and energy filters, Aquilos FIB-SEM, etc.) and to provide excellent hands-on training. Please send your cover letter and resume to raul.pad...@umassmed.edu and roger.cr...@umassmed.edu All the best, Raul Padron & Roger Craig ######################################################################## To unsubscribe from the CCP4BB list, click the following link: https://www.jiscmail.ac.uk/cgi-bin/WA-JISC.exe?SUBED1=CCP4BB&A=1 This message was issued to members of www.jiscmail.ac.uk/CCP4BB, a mailing list hosted by www.jiscmail.ac.uk, terms & conditions are available at https://www.jiscmail.ac.uk/policyandsecurity/
