[ccp4bb] PhD Positions in Mainz/Germany

[Wolf, Eva]

Dear all,

2 PhD positions are available immediately in the research group of Eva Wolf in 
Mainz (Germany). Research in the Wolf group is focused on the structural, 
biochemical and biophysical analyses of proteins involved in the circadian 
(day-time dependent) and circalunar (monthly) regulation of cellular, 
physiological and behavioral processes. We recently described molecular 
mechanisms and Cryo-EM structures of a marine cryptochrome (L-Cry), which is 
involved in the synchronization of moon-controlled maturation rhythms of marine 
worms with the lunar cycle (Pöhn, Krishnan et al, Nat Comm 2022; Vu, Behrmann 
et al, Nature Comm 2023; Zurl et al, PNAS 2022). The prospective PhD students 
will further characterize LCry’s reponses to sunlight and moonlight and its 
molecular interactions with downstream ligands. In a highly interdisciplinary 
approach, they will apply a wide range of techniques including UV/VIS 
spectroscopy, biochemical and biophysical protein interaction studies, protein 
expression and purification, X-ray crystallography, Cryo-EM, pulldown/MS, 
molecular biology and functional cell-based assays.

Candidates with a strong interest in structural biology, protein biochemistry, 
biophysics and structure-function relationship and a significant previous 
exposure to these research areas during their master education are encouraged 
to apply. Please send your application including your CV, motivation letter, 
certificates and contact details for two referees in one pdf file to Eva Wolf 
(evawo...@uni-mainz.de). We encourage PhD 
candidates to also apply to the International PhD Program (IPP) of the Mainz 
Institute of Molecular Biology (IMB) before April 17th. Information about the 
IPP can be found under 
https://www.imb.de/students-postdocs/international-phd-programme/apply-to-ipp .

-

Prof. Dr. Eva Wolf

Structural Chronobiology

University and IMB Mainz

Hanns-Dieter-Hüsch-Weg 17

55128 Mainz, Germany

evawo...@uni-mainz.de

https://chrono-wolf.biologie.uni-mainz.de/




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[ccp4bb] PhD Position in Structural Biology in Mainz/Germany

[Wolf, Eva]

PhD Position in Mainz/Germany

Dear all,

a PhD position in Structural Biology is available in the research group of Eva 
Wolf in Mainz (Germany). Research in the Wolf group is focused on the 
structural, biochemical and biophysical analyses of proteins involved in 
circadian (day-time dependent) regulation. To elucidate the molecular 
mechanisms underlying circadian gene regulation and light synchronization, the 
PhD student will apply a wide range of techniques including X-ray 
crystallography, biochemical and biophysical protein interaction studies, 
bioinformatics, UV/VIS spectroscopy, protein expression and purification, 
molecular biology and functional cell-based assays.

The prospective PhD student will be affiliated with the International PhD 
Program (IPP) of the Mainz Institute of Molecular Biology (IMB). Candidates 
with a strong interest in structural biology, protein biochemistry and 
structure-function relationship and a significant previous exposure to these 
research areas during their master education are encouraged to apply.

PhD candidates must register with the IPP 
(https://www.imb.de/students-postdocs/international-phd-programme) before May 
3rd 2022 and send their full application to the IPP before May 10th 2022. 
Additionally, please send your application including your CV, motivation 
letter, certificates and contact details for two referees in one pdf file to 
Eva Wolf (evawo...@uni-mainz.de).


With best regards,



-

Prof. Dr. Eva Wolf

Structural Chronobiology

University and IMB Mainz

Hanns-Dieter-Hüsch-Weg 17

55128 Mainz, Germany

evawo...@uni-mainz.de




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[ccp4bb] PhD Position in Mainz, Germany

[Wolf, Eva]

Dear all,

a PhD position in Structural Biology is available in the research group of Eva 
Wolf in Mainz (Germany). Research in the Wolf group is focused on the 
structural, biochemical and biophysical analyses of proteins involved in 
circadian (day-time dependent) regulation. To elucidate the molecular 
mechanisms underlying circadian gene regulation and light synchronization, the 
PhD student will apply a wide range of techniques including X-ray 
crystallography, biochemical and biophysical protein interaction studies, 
bioinformatics, UV/VIS spectroscopy, protein expression and purification, 
molecular biology and functional cell-based assays.

The prospective PhD student will be affiliated with the International PhD 
Program (IPP) of the Mainz Institute of Molecular Biology (IMB) and with the 
Research Training Group “Genevo” (https://www.genevo-rtg.de/). Candidates with 
a strong interest in structural biology, protein biochemistry and 
structure-function relationship and a significant previous exposure to these 
research areas during their master education are encouraged to apply.

Please send your application including your CV, motivation letter, certificates 
and contact details for two referees in one pdf file to Eva Wolf 
(evawo...@uni-mainz.de). Additionally, please 
apply to the Genevo PhD Program (https://www.genevo-rtg.de/) before January 
20th, 2022.



With best regards,



Eva Wolf

Professor for Structural Biology

University and IMB Mainz

Hanns-Dieter-Hüsch-Weg 17

55128 Mainz, Germany

E-mail: evawo...@uni-mainz.de




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[ccp4bb] PhD Position in Mainz, Germany

[Wolf, Eva]

Dear all,

a PhD position in Structural Biology is available in the research group of Eva 
Wolf in Mainz (Germany). Research in the Wolf group is focused on the 
structural, biochemical and biophysical analyses of proteins involved in 
circadian (day-time dependent) regulation. To elucidate the molecular 
mechanisms underlying circadian gene regulation and light synchronization, the 
PhD student will apply a wide range of techniques including X-ray 
crystallography, biochemical and biophysical protein interaction studies, 
bioinformatics, UV/VIS spectroscopy, protein expression and purification, 
molecular biology and functional cell-based assays.

The prospective PhD student will be affiliated with the International PhD 
Program (IPP) of the Mainz Institute of Molecular Biology (IMB) and with the 
Research Training Group “Genevo” (https://www.genevo-rtg.de/). Candidates with 
a strong interest in structural biology, protein biochemistry and 
structure-function relationship and a significant previous exposure to these 
research areas during their master education are encouraged to apply.

Please send your application including your CV, motivation letter, certificates 
and contact details for two referees in one pdf file to Eva Wolf 
(evawo...@uni-mail.de). Additionally, please apply 
to the Genevo PhD Program (https://www.genevo-rtg.de/) before January 20th, 
2022.



With best regards,



Eva Wolf

Professor for Structural Biology

University and IMB Mainz

Hanns-Dieter-Hüsch-Weg 17

55128 Mainz, Germany




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[ccp4bb] 2 PhD positions in Mainz/Germany

[Wolf, Eva]

Dear all,

I am looking for two PhD students to join our research group in Mainz/Germany.

Here is the ad:

2 PhD positions in Structural Biology at JGU/IMB Mainz, Germany

Two PhD positions are available in the group of Eva Wolf at the Johannes 
Gutenberg University (JGU) and

the Institute of Molecular Biology (IMB) in Mainz, Germany. Research in the 
Wolf group is focused on the

structural, biochemical and biophysical analysis of proteins involved in 
circadian (day-time dependent)

regulation and light-synchronization.

To elucidate the molecular mechanisms underlying circadian regulation, the PhD 
student will apply a wide range

of techniques including 3D-structural analyses (e.g. X-ray crystallography, 
Cryo-EM, SAXS, Crosslink-MS),

biochemical and biophysical protein interaction studies as well as UV/VIS 
spectroscopy. To produce highly pure

proteins and protein complexes for these applications, she/he will perform 
cloning, recombinant protein expression

(E.coli, insect cells) and protein purification using FPLC systems. Within 
collaborations, she/he will also analyze

clock protein functions in cell-based approaches and in vivo systems.

Candidates with a strong interest in structural biology, protein biochemistry, 
protein structure-function relationship

and a significant previous exposure to these research areas during their master 
education are encouraged to apply.


Please send your application including your CV, motivation letter, certificates 
and contact details for 2 references in

one pdf-file to Eva Wolf (evawo...@uni-mainz.de). 
The deadline for this application is November 4th 2020.


The prospective PhD student will also be affiliated with IMB’s International 
PhD program (IPP) and must have a

good command of English. PhD candidates must also apply to the International 
PhD Programme

(IPP, https://www.imb.de/students-postdocs/international-phd-programme).

The deadline for registration at the IPP is November 27th 2020.


With best regards,

Eva

Prof. Dr. Eva Wolf
Structural Chronobiology
IMB and University Mainz
Ackermannweg 4
55128 Mainz, Germany
evawo...@uni-mainz.de
https://www.imb.de/research/wolf/research/




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[ccp4bb] PhD position in Germany

[Wolf, Eva]

Dear all,

Please find below the advertisement for a PhD position in our research group:

---

PhD position in Structural Biology at JGU/IMB Mainz, Germany
A PhD position is available in the group of Eva Wolf at the Johannes Gutenberg 
University
(JGU) and the Institute of Molecular Biology (IMB) in Mainz, Germany. Research 
in the Wolf
group is focused on the structural, biochemical and biophysical analysis of 
proteins involved
in circadian (day-time dependent) regulation (e.g. Czarna et al, Cell 2013; 
Schmalen et al,
Cell 2014) and in genome maintenance (e.g. Witosch et al, NAR 2014).
To elucidate the molecular mechanisms underlying circadian gene regulation and 
circadian
physiology, the PhD student will apply a wide range of techniques including 
3D-structural
analyses (e.g. X-ray crystallography, Cryo-EM, SAXS, Crosslink-MS), biochemical 
and
biophysical protein interaction studies as well as UV/VIS spectroscopy. To 
produce highly
pure proteins and protein complexes for these applications, she/he will perform 
cloning,
recombinant protein expression (E.coli, insect cells) and protein purification 
using FPLC
systems. Within collaborations, she/he will also analyze clock protein 
interactions and protein
functions in cell-based approaches and in in vivo systems. Candidates with a 
strong interest
in structural biology and protein biochemistry combined with a significant 
previous exposure
to these research areas during their master education are encouraged to apply.
The prospective PhD student will be affiliated with IMB’s International PhD 
program (IPP)
and must have a good command of English. PhD candidates must officially apply 
via the
International PhD Programme (IPP, 
www.imb-mainz.de/students-postdocs/international-phd-programme).
 The deadline for registration at the IPP is May 26th 2020. Informal inquiries 
should be addressed
to Eva Wolf (evawo...@uni-mainz.de).

With best regards,

Eva Wolf

---
Prof. Dr. Eva Wolf
Structural Chronobiology
IMB and University Mainz Ackermannweg 4 55128 Mainz, Germany
evawo...@uni-mainz.de
https://www.imb.de/research/wolf/research/



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[ccp4bb] PhD position in Structural Biology

[Wolf, Eva]

Dear all,

Please find below the advertisement for a PhD position in our research group:

---

 PhD position in Structural Biology at JGU/IMB Mainz, Germany

 A PhD position is available in the group of Eva Wolf at the Johannes Gutenberg 
University
(JGU) and the Institute of Molecular Biology (IMB) in Mainz, Germany. Research 
in the Wolf
group is focused on the structural, biochemical and biophysical analysis of 
proteins involved
in circadian regulation (e.g. Czarna et al, Cell 2013; Schmalen et al, Cell 
2014). To elucidate
the molecular mechanisms underlying circadian (day-time dependent) gene 
regulation and
its adaptive evolution, the PhD student will structurally and functionally 
characterize circadian
clock proteins of various organisms. He/she will apply a wide range of 
techniques including
recombinant protein expression (E.coli, insect cells), protein purification, 
X-ray crystallography,
biochemical and biophysical protein interaction studies and molecular biology 
to understand
how evolution engineers the 3D-structure, activity and molecular interactions 
of clock proteins
to tune their roles in gene regulation. Within collaborations, she/he will also 
analyze the
molecular interactions, functional activities and evolution of clock proteins 
using cell-based
approaches as well as behavioral and phylogenetic studies.
The project will be performed within a new DFG funded research training group 
(RTG) on
“Gene regulation in 
evolution”,
 which enables extensive interdisciplinary collaborations and
networking.  Candidates with a strong interest in structural biology, protein 
biochemistry,
biophysics, protein structure-function relationship and evolutionary biology 
and a significant
previous exposure to these research areas during their master education are 
encouraged to apply.
The prospective PhD student will also be affiliated with IMB’s International 
PhD program (IPP)
and must have a good command of English. The Wolf group is currently located at 
the IMB
(www.imb.de).

PhD candidates must officially apply via the International PhD Programme (IPP, 
www.imb.de/PhD).

The deadline for registration at the IPP is May 22nd 2019.

Informal enquires should be addressed to Eva Wolf 
(evawo...@uni-mainz.de).


With best regards,

Eva

-

Prof. Dr. Eva Wolf
Structural Chronobiology
IMB and University Mainz
Ackermannweg 4
55128 Mainz, Germany
evawo...@uni-mainz.de
https://www.imb.de/research/wolf/research/






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[ccp4bb] Postdoc position in Structural Biology at JGU/IMB Mainz, Germany

[Wolf, Eva]

Dear all,

We are looking for a highly qualified and motivated postdoctoral researcher 
with a strong background
in structural biology and an interest in genome maintenance and circadian 
clocks.

Here is the advertisement for the position:

Postdoc position in Structural Biology at JGU/IMB Mainz, Germany

A postdoc position is available in the group of Eva Wolf at the Johannes 
Gutenberg University (JGU)
and the Institute of Molecular Biology (IMB) in Mainz, Germany. The position is 
available for a period
of 4 years. Salary will be according to German public service payment agreement 
(TV-L 13; 100%).

Research in the Wolf group is focused on the structural, biochemical and 
biophysical analysis of
protein complexes involved in circadian clocks (e.g. Czarna et al, Cell 2013; 
Schmalen et al, Cell 2014) and in their interconnection to genome maintenance, 
specifically via the protein Timeless. Following up on our Cryo-EM structure of 
a mammalian Timeless–Tipin-RPA complex (Witosch et al,
NAR 2014), this project aims at 3D-structures of Timeless complexes with 
replication fork associated
proteins and their subsequent biological validation, e.g. in mutational 
studies. It will involve a wide
range of techniques including recombinant protein expression (E.coli, insect 
cells), protein purification,
Cryo-EM, X-ray crystallography as well as complementary biochemical, 
biophysical and cell-based
methods to study protein interactions and activities.
The successful postdoc candidate will have solid practical experience in 
Cryo-EM and/or X-ray crystallography, in recombinant protein expression 
(preferentially insect cells and E.coli) and in protein
purification (preferentially purification of protein complexes). Additional 
practical experience with
biochemical and quantitative biophysical analyses of protein interactions is an 
advantage. She/he will
hold a PhD in a relevant discipline and be fluent in English (written and 
spoken).

The Wolf group is currently located at the Institute of Molecular Biology (IMB, 
www.imb.de).
IMB is a center for basic research, which is generously funded by the 
Boehringer Ingelheim Foundation
and the state of Rhineland-Palatinate and is located on the campus of Mainz 
University, Germany.

To apply, please send a single PDF file containing your cover letter stating 
research interests and
expertise, a CV, scanned certificates and contact details of at least two 
references to
sek...@uni-mainz.de before January 29th 2019. 
Informal enquires should be addressed to
Eva Wolf (evawo...@uni-mainz.de). The additional 
application to the IMB Postdoc Programme
(IPPro, post...@imb.de, www.imb.de/postdocs) is 
encouraged.


With best regards,

Eva



Prof. Dr. Eva Wolf
Structural Chronobiology
IMB and University Mainz
Ackermannweg 4
55128 Mainz, Germany
evawo...@uni-mainz.de

www.imb.de/research/wolf







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[ccp4bb] Postdoc and PhD positions in Structural Biology

[Wolf, Eva]

Postdoc and PhD positions in Structural Biology



A postdoc position and a PhD position are available in the laboratory of Prof. 
Eva Wolf at the Biology department of the Johannes Gutenberg University (JGU) 
Mainz, Germany.

The positions are available immediately for an initial period of 3 years. 
Salary will be according to German public service payment agreement (TV-L 13; 
100% for postdoc position, 65% for PhD position).



Research in the Wolf group is focused on the structural (mostly X-ray 
crystallography), biochemical and biophysical analysis of proteins/protein 
complexes involved in the regulation and light-synchronization of the inner 
circadian clock (e.g. Czarna et al (2013) Cell, 153(6):1394-405; Schmalen et al 
(2014) Cell, 157(5):1203-1215). Circadian clocks generate daily (24 h) rhythms 
of physiology, metabolism and behaviour and thereby critically affect fitness, 
health and disease.

Projects will involve a wide range of techniques including cloning, recombinant 
protein expression, protein purification, crystallization and X-ray 
crystallography as well as complementary biochemical and biophysical methods to 
study protein structures, interactions and activities.



The Wolf group is currently located at the Institute of Molecular Biology (IMB) 
(www.imb-mainz.de/wolfhttp://www.imb-mainz.de/wolf). IMB is a Centre of 
Excellence for Life Sciences, which is funded by the Boehringer Ingelheim 
Foundation and located on the campus of the Johannes Gutenberg University 
Mainz, Germany.



The successful postdoc candidate will have solid practical experience in 
recombinant protein expression (preferably bacterial and eukaryotic expression 
systems), in protein purification and in macromolecular X-ray crystallography. 
Additional experience with biochemical, biophysical or spectroscopic analyses 
of purified proteins is an advantage. She/he will hold a PhD in a relevant 
discipline.



The successful PhD candidate will have a strong interest in structural biology 
and protein biochemistry as well as significant previous exposure to these 
research areas during the master education.



To apply, please send a single PDF file containing your cover letter stating 
research interests and expertise, a CV, scanned certificates and contact 
details of at least two references to 
sek...@uni-mainz.demailto:sek...@uni-mainz.de before May 25th 2015. Informal 
enquires should be addressed to Eva Wolf 
(evawo...@uni-mainz.demailto:evawo...@uni-mainz.de). PhD candidates also have 
to officially apply via IMB's International PhD Programme 
(www.imb-mainz.dehttp://www.imb-mainz.de).







With kind regards,



Eva Wolf

[ccp4bb] Postdoc and PhD positions in Structural Biology

[Wolf, Eva]

Postdoc and PhD positions in Structural Biology

 A postdoc position and three PhD positions are available in the laboratory of 
Prof. Eva Wolf at the Johannes Gutenberg University (JGU) and Institute of 
Molecular Biology (IMB) in Mainz, Germany.

The Wolf group is currently located at the IMB 
(www.imb-mainz.de/wolfhttp://www.imb-mainz.de/wolf). IMB is a Centre of 
Excellence for Life Sciences, which is funded by the Boehringer Ingelheim 
Foundation and located on the campus of the Johannes Gutenberg University, 
Mainz, Germany.
Research in the Wolf group is focused on the structural, biochemical and 
biophysical analysis of circadian clock proteins, which generate circadian 
(24h) rhythms in physiology, metabolism and behaviour and synchronize them with 
the environmental light-dark cycle. Projects will include x-ray crystallography 
with ample support from other biochemical, molecular biology and spectroscopic 
techniques such as recombinant protein expression, protein purification, 
biochemical and biophysical protein-protein interaction analyses, UV/VIS- and 
CD spectroscopy (e.g. Czarna et al, Cell 2013;153(6):1394-405; Schmalen et al, 
Cell 2014;157(5):1203–1215).
The successful postdoc candidate will hold a PhD in a relevant discipline and 
have solid practical experience in recombinant protein expression using E.coli 
and insect cells, protein purification and macromolecular X-ray 
crystallography. Additional experience with biochemical and biophysical 
protein-protein interaction analyses or UV/VIS spectroscopy is an advantage.
For the PhD positions, candidates with a strong interest in structural biology 
and protein biochemistry and previous exposure to these research areas during 
their master education are encouraged to apply.

To apply, please send a single PDF file containing your cover letter stating 
research and career interests, CV, scanned certificates and contact details of 
at least two references to sek...@uni-mainz.demailto:sek...@uni-mainz.de. 
Informal enquires should be addressed to Eva Wolf 
(evawo...@uni-mainz.demailto:evawo...@uni-mainz.de).

PhD candidates also have to officially apply via IMB’s International PhD 
Programme before July 5, 2014 
(www.imb-mainz.de/PhDhttp://www.imb-mainz.de/PhD).