Once thing I don't fully understand: do you have a cleaved density or a cleaved
peptide? If your peptide is sitting in a binding site, and that you can see
only the part inside the pocket, with the rest supposably sitting in a 'more
opened' part of the molecule, or else outside of the molecule,
Dear Dipankar,
as Bonsor mentioned, 2-3 weeks is something completely different from the few
hours normally used for enzyme assays. A lot may happen during the long
crystallization that does not happen in the assay. Also, your enzyme will still
have the remainder of the catalytic machinery