Yes, that's a good point--you can't really discredit Rmerge (it's just
a mathematical expression, after all, which must be translated vis a
vis redundancy), but you can show that the other R's are pleasanter
ways to represent the data.
Jacob
On Tue, Dec 6, 2011 at 3:02 PM, Anastassis Perrakis wr
Also
Nat Struct Biol. 1997 Apr;4(4):269-75.
Improved R-factors for diffraction data analysis in macromolecular
crystallography.
Diederichs K, Karplus PA.
But none of these are in any way 'discrediting' Rmerge, they are just proposing
more statistically sound alternatives. That is not the same .
On Tue, 2011-12-06 at 13:43 -0600, Jacob Keller wrote:
> The question is: "is there a reference in which Rmerge has been
> thoroughly, clearly, and authoritatively discredited as a data
> evaluation metric in the favor of Rmeas, Rpim, etc., and if so, what
> is that reference?"
>
Aren't these suf
On Tuesday, December 06, 2011 11:43:05 am Jacob Keller wrote:
> Hi Ethan, thanks for pushing me to clarify--see below.
>
> >> I hate to broach this subject again due to its wildly controversial
> >> nature, but I was wondering whether there was any reference which
> >> systematically analyses reso
Hi Ethan, thanks for pushing me to clarify--see below.
>> I hate to broach this subject again due to its wildly controversial
>> nature, but I was wondering whether there was any reference which
>> systematically analyses resolution cutoffs as a function of I/sig,
>> Rmerge, Rmeas, Rpim, etc. I st
On Tuesday, December 06, 2011 09:13:03 am Jacob Keller wrote:
> Dear Crystallographers,
>
> I hate to broach this subject again due to its wildly controversial
> nature, but I was wondering whether there was any reference which
> systematically analyses resolution cutoffs as a function of I/sig,
>
Dear Crystallographers,
I hate to broach this subject again due to its wildly controversial
nature, but I was wondering whether there was any reference which
systematically analyses resolution cutoffs as a function of I/sig,
Rmerge, Rmeas, Rpim, etc. I strongly dislike Rmerge/Rcryst for
determinin