Dear Colleagues,

We have an immediate job opening in our protein sciences group for a
molecular biologist/protein expression scientist (Application link and
details provided below). I would greatly appreciate if you can forward to
suitable candidates.

33174BR
<https://sjobs.brassring.com/TGnewUI/Search/home/HomeWithPreLoad?PageType=JobDetails&noback=0&partnerid=169&siteid=5140&jobid=798102#jobDetails=798102_5140>

Best regards,
Rajesh Kumar Prakash

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Scientist I, Small Molecule Protein Science

US-MA-Cambridge

*Summary*

The Physical Biochemistry department is seeking an independent and highly
motivated Molecular Biologist to join the Small Molecule Protein Sciences
group (SMPS) at the Scientist I level. The SMPS is responsible for
providing high quality protein reagents for small molecule targets to the
Bioassays, Biophysics and the Structural biology groups.


Job Description

The Physical Biochemistry department is seeking an independent and highly
motivated Molecular Biologist to join the Small Molecule Protein Sciences
group (SMPS) at the Scientist I level. The SMPS is responsible for
providing high quality protein reagents for small molecule targets to the
Bioassays, Biophysics and the Structural biology groups. The successful
candidate must possess a broad set of skills, including Molecular Biology
and expression of proteins from bacterial and eukaryotic hosts. Special
emphasis will be given to candidates with the ability to carry out rapid
construct designs and purification. The selected individual will have the
opportunity to work in cross-functional teams and should be able to clearly
communicate their results and accomplishments to a broad audience at team
meetings and in written reports.

*Qualifications*

• The selected candidate should exhibit expertise in Molecular Biology,
including a variety of modern cloning approaches, construct design,
sequence bioinformatics and tagging strategies.
• The ideal candidate would have experience expressing IMP (channels,
transporters, GPCRs) expression strategies from multiple hosts.
• The candidate should have demonstrated by publications or other means, an
ability to carry out a variety of construct designs, expression strategies
and usage of multiple hosts. In addition, a sound knowledge of downstream
small and large scale purification will be highly valued.
• Good experience in parallel, high throughput approaches to cloning and
small scale expression will be necessary.
• Working knowledge of Akta or equivalent instruments will be considered an
asset.
• Bioinformatics programming (PERL, PYTHON) to decipher protein domains,
sequence and structural alignments will be considered an asset.
• This candidate will also work with external CROs to coordinate molecular
biology, expression and purification handoffs.
• Must be adept at following protocols and should have the scientific
experience to modify them when the situation arises.
• The candidate should have excellent verbal and written communication
skills. Clear scientific presentation skills at project and team meetings
are a must.
• Must be excellent in organization skills. The candidate is expected to
document all aspects of the experiments performed and be able to conduct
independent research to collect and archive all necessary information from
the literature.
• Demonstration of innovative approaches to problem solving is essential.

*Education*

Ph.D in Molecular Biology, Biochemistry or other suitable discipline.

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