Re: [ccp4bb] Structural Importance of Methionine

2020-08-07 Thread samer halabi
Re: [ccp4bb] Structural Importance of Methionine   Hi Samer, In addition to what has been already mentioned to you, there are also the two well illustrated cases of methionine rich domains. - in the case of the M (for Met rich) domain of the Signal Recognition Particle protein SRP54/Ffh

Re: [ccp4bb] Structural Importance of Methionine

2020-08-07 Thread Jessica Bruhn
e-mail: gau...@mcb.harvard.edu > ___ > > > > *From:* CCP4 bulletin board * On Behalf Of *Pascal > Egea > *Sent:* Friday, August 7, 2020 10:21 AM > *To:* CCP4BB@JISCMAIL.AC.UK > *Subject:* Re: [ccp4bb] Struct

Re: [ccp4bb] Structural Importance of Methionine

2020-08-07 Thread samer halabi
, 2020 10:21 AM To: CCP4BB@JISCMAIL.AC.UK Subject: Re: [ccp4bb] Structural Importance of Methionine   Hi Samer, In addition to what has been already mentioned to you, there are also the two well illustrated cases of methionine rich domains. - in the case of the M (for Met rich) domain of

Re: [ccp4bb] Structural Importance of Methionine

2020-08-07 Thread samer halabi
Dear Sahil,I quickly  read part of the paper that you sent. It is very interesting. Thank you for sharing. Looking forward to read it in details.Best regards,Samer On Friday, August 7, 2020, 02:19:20 PM GMT+1, Sahil Batra wrote: Hi Samer, I came across this interesting article recentl

Re: [ccp4bb] Structural Importance of Methionine

2020-08-07 Thread Gaudet, Rachelle
edu> ___ From: CCP4 bulletin board On Behalf Of Pascal Egea Sent: Friday, August 7, 2020 10:21 AM To: CCP4BB@JISCMAIL.AC.UK Subject: Re: [ccp4bb] Structural Importance of Methionine Hi Samer, In addition to what has been a

Re: [ccp4bb] Structural Importance of Methionine

2020-08-07 Thread Pascal Egea
Hi Samer, In addition to what has been already mentioned to you, there are also the two well illustrated cases of methionine rich domains. - in the case of the M (for Met rich) domain of the Signal Recognition Particle protein SRP54/Ffh involved in promiscuous binding of the N-terminal hydrophobic

Re: [ccp4bb] Structural Importance of Methionine

2020-08-07 Thread Sahil Batra
Hi Samer, I came across this interesting article recently, that discusses the significance of unusually high content of Met in the polymerization inducing domain of spider silk protein ( https://www.nature.com/articles/s41467-019-12365-5). Methionines provide a 'mobilization' to the hydrophobic co

[ccp4bb] Structural Importance of Methionine

2020-08-07 Thread samer halabi
Dear All,I am working on structures where Methionine is important in binding of peptides to the MHC protein complex.Would anyone kindly like to share their knowledge about anything they find it important about this particular amino acid structurally? Sharing a paper or just few comments will be