Dear colleagues, with this message I would like to announce our workshop entitled: *"Strategic pipeline planning: from sample preparation to 3D structure determination with bio SAXS and other biophysical techniques"* to be held at the National Hellenic Research Foundation (NHRF) in Athens from April 5th to April 10th, 2014.
*The workshop *will provide training on creating a roadmap towards determining the 3D structure of a macromolecular target including troubleshooting and rational decision-making with emphasis on Bio SAXS. The sessions will include: - *Structural Biology in Europe 2014 onwards *(ESFRI actions Instruct - a success story, Large scale facilities in Europe & Opportunities for transnational access) - *Perspectives in structural biology *(An overview of additional main stream methods for structural biology: X-ray crystallography, NMR, X-ray imaging, ΕΜ) - *Sample preparation *(Key objectives and how to benchmark the success of a strategy, bottlenecks and troubleshooting, decision making on method selection for 3D structure determination) - *Bio SAXS at the forefront of structural biology *(Basic principles of SAXS, Supporting biophysical techniques e.g. Dynamic Light Scattering, ITC, SAXS data analysis software, in vitro and in silico SAXS challenges) - *Career development* ("Mobstacles" and prospects for young scientists in the frame of Horizon 2020) *Target Group: *PhD students and post-doctoral scientists, currently working in the structural biology field and have already some experience in working with macromolecules. Experienced researchers will also be considered but priority will be given to younger scientists. A total of 25 participants will be accepted in the course. *Selection process*: The Biostruct-X and local organizers will be responsible for the selection process to ensure that equivalent criteria will be applied. The applicants will be expected to send - a CV (max. 2 pages), - a motivation letter (max. 1 page) explaining why they wish to participate and what they expect from the course and - a reference letter. ************* Deadline: Wednesday, March 5th, 2014 ********** *Benefits: *Participants that have been accepted to the course are offered : - to *send their protein samples (>90% pure) to the Sample Preparation and Characterization (SPC) facility at the EMBL in Hamburg*. The SPC will offer a preliminary sparse matrix screen that can be customized to the particular sample, complementary characterization by thermal shift assay, dynamic light scattering and mass spectrometry. *The preliminary results of this characterization will be discussed during the workshop*. For more information, please visit the SPC website: https://htx.embl-hamburg.de/htxlab/ - *a limited number of fellowships* to be awarded to participants coming from INSTRUCT member countries (Belgium, Czech Republic, France, Germany, Israel, Italy, Netherlands, Portugal, Spain, Sweden, United Kingdom) awarded by INSTRUCT (http://www.structuralbiology.eu). *Host:* The event will be hosted by NHRF, coordinator of Instruct-EL, the national distributed research infrastructure that functions as a hub for structural biology in South East European area and Cyprus. *The workshop is organized in conjunction with the International Conference on Research Infrastructures (ICRI-2014) that will also be held in Athens 2-4 April, http://www.icri2014.eu <http://www.icri2014.eu> * *Registration fee*: EURO 50 for academic participants and EURO 1000 for participants coming from industry. *Confirmed speakers in alphabetical order include:* P. Agianian, T. Bergfors, J-M. Carazo, M. Graewert, M. Kokkinidis, P. Konarev, R. Meijers, G. Nounesis, E. Pereiro, M. Petoukhov, S. Pispas, E. Saridakis, S. Savvides, Th. Schneider, G. Spyroulias, P. Shaw-Stewart, Ef. Stratikos, D. Stuart, D. Svergun, C.E. Vorgias, M. Weiss, M. Wilmanns *Organizing committee:* *Local organizers :**National Hellenic Research Foundation (NHRF, host) *(E.D. Chrysina, V. Papadimitriou, G. Sotiroudis, A. Xenakis, M. Zervou, P. Zoumpoulakis) *Hellenic Crystallographic Association *(I.M. Mavridis, S.E. Zographos) *ICRI-2014 organizers*: *European Commission*, Directorate General for Research & Innovation (Octavi Quintana Trias, Director of ERA policy) *"Athena"- Research and Innovation Center (on behalf of the Greek presidency/GSRT) *(Yannis Ioannidis, President and General Director) *Lead contact:* Dr Evangelia Chrysina, echrys...@eie.gr *More information will appear shortly on NHRF website*: http://www.eie.gr/index-en.html The workshop is supported by: - *European Commission, Seventh Framework Programme (FP7)* - *Biostruct-X *(http://www.biostruct-x.eu) - *INSTRUCT *(http://www.structuralbiology.eu) - *DECTRIS *(http://www.dectris.com) - *Douglas Instruments *(http://www.douglas.co.uk) - *Rigaku *(http://www.rigaku.com) - *Anelis Analytical Environmental Life Industrial Sciences *( http://www.anelis.gr) Looking forward to receiving your application and welcoming you in Athens in April. On behalf of the organising committee, Evangelia Chrysina Instruct-EL coordinator -- Dr. Evangelia D. Chrysina Chemical Engineer-National Technical University of Athens (NTUA), Greece Molecular Structural Biologist- PhD in Biochemistry, University of Bath, UK Marie Curie Fellow (1997-2000) -- National Hellenic Research Foundation (NHRF) Institute of Biology, Medicinal Chemistry and Biotechnology (IBMCB) 48, Vassileos Constantinou Avenue Athens GR-11635, Greece E-mail: echrys...@eie.gr, ec...@eie.gr Tel. 00302107273851, 00306937443207 Fax 00302107273831