Dear all, I am now working on a very low resolution phase determination (around 4.5A with hg anomalous signal around 5.5 A). I can find the Hg sites and get the phase, but the density map is not so good. Two components of my protein complex (about 1/3) has a homologue model which is also can not be found using Phaser. My native data is 3.5 A.
Can I combine the experimental phase and homology model to improve electron density? Is there anybody can help find which program can work on this? Thank you. Lisa
