Re: [ccp4bb] neg density/high B on sidechains

2020-04-29 Thread Clemens Vonrhein
Dear Len, maybe a slight side-track, but you could consider taking one step back and applying a slightly different approach to data-processing - something we call "F(early)-F(late)" maps in autoPROC [1]. Why could that be useful here? Because it might allow you to (1) differentiate between

[ccp4bb] Micro-ED "pushing the frontiers" again ... but which frontiers?

2020-04-29 Thread Gerard Bricogne
Dear all, There have been warnings circulating for quite some time now about the possible impact of SARS-CoV-2 on the cognitive abilities of patients who have recovered from Covid-19, and I fear that I have reasons to worry about possibly having fallen victim to these ... . I came

[ccp4bb] Sanofi Postdoctoral Fellowship: Computational Scientist for Antibody Engineering (Framingham, MA)

2020-04-29 Thread Qiu, Yu PH/US
To the ccp4bb community, If you have Ph. D. in data science, artificial intelligence, machine learning, deep learning, computer sciences, bioinformatics, mathematics, computational biology, or related field, and interested in applying cutting-edge technology to antibody/protein engineering,

Re: [ccp4bb] disinfecting keyboards

2020-04-29 Thread Tristan Croll
I once knew a particularly germaphobic IT manager who used to absolutely *everything* via ssh or remote desktop from his own laptop, even when he was physically in front of the user's computer. If feasible, that approach would actually seem quite smart in the current environment. On

Re: [ccp4bb] disinfecting keyboards

2020-04-29 Thread Dominika Borek
http://www.viziflex.com/disposables/universal-disposable-50-pack/ D. On 2020-04-29 01:53 PM, Tim Gruene wrote: Dear all, can you make suggestions for how to disinfect computer keyboards, and instrument panels? Our facility is going to reboot next week, with shifts so that people don't meet.

Re: [ccp4bb] disinfecting keyboards

2020-04-29 Thread James Holton
Keyboards are cheap.  Why not everyone get their own? Then we can all stop fighting about whether the key should be shaped like an "L" or not. -James Holton MAD Scientist On 4/29/2020 11:53 AM, Tim Gruene wrote: Dear all, can you make suggestions for how to disinfect computer keyboards,

Re: [ccp4bb] disinfecting keyboards

2020-04-29 Thread James Holton
Because as soon as I put on gloves my nose starts to itch. On 4/29/2020 12:37 PM, gianluca.sant...@esrf.fr wrote: ISO keyboards are bad. But why not just using disposable gloves to operate the instruments? On April 29, 2020 9:30:19 PM GMT+02:00, James Holton wrote: Keyboards are cheap. 

Re: [ccp4bb] 2fofc maps from refmac twinned refinement - clarify?

2020-04-29 Thread James Holton
Yes, they are "de-twinned".  There is really no other way to do it. Without de-twinning you'd be looking at a map of two overlapping structures.  How do you turn a single observation of the sum of intensities from two different hkls into two different Iobs values? You need to know the ratio. 

Re: [ccp4bb] disinfecting keyboards

2020-04-29 Thread Diana Tomchick
?You could try doing what my technician does with her keyboard; she wraps it in a clear, thin food wrap that can be taped to the back of the keyboard. This is usually done to keep food and other things (liquids) from damaging the keyboard, but you could simply replace the wrap every time

Re: [ccp4bb] disinfecting keyboards

2020-04-29 Thread Sravya Mounika Kantamneni
How about using keyboard guards and dissecting them as usual? Regards, Sravya > On Apr 29, 2020, at 8:53 PM, Tim Gruene wrote: > > Dear all, > > can you make suggestions for how to disinfect computer keyboards, and > instrument panels? > > Our facility is going to reboot next week, with

Re: [ccp4bb] disinfecting keyboards

2020-04-29 Thread Ankita Singla
Injecting the disinfectant might not be much functional. Maybe the Royal Society of London have thoughts to add to this. Can we publish it and call it a computer hazard! *laughs* Ankita Singla Masters student All India Institute of medical sciences New Delhi On Thu 30 Apr, 2020, 12:54 AM , <

Re: [ccp4bb] disinfecting keyboards

2020-04-29 Thread Andrea Thorn
Hi Tim! 100% alcohol is less effective than 80%, and in order to completely be sure, the keyboard needs not only to be wiped. One can buy keyboards that can be disinfected because they are waterproof, such as the Cherry JK-1068DE-2 for about 50 €. We clean the keyboards in our lab

Re: [ccp4bb] disinfecting keyboards

2020-04-29 Thread Crissy Lynette Tarver
Hello, I agree with wiping instruments down with 75-80% ethanol (as used to clean during cell culture). However, the BEST precaution is simply not touching your face and washing your hands for 20-30 seconds after touching anything. I made it a habit of scrubbing my hands with Hibiclens after

Re: [ccp4bb] disinfecting keyboards

2020-04-29 Thread David Schuller
If you are going that route, it would make sense to locate the UV lamps in the X-ray hutch, since those already have safety interlocks, etc. The X-ray beam itself is too directional to uniformly cover much. On 2020-04-29 15:48, Eduardo Rodríguez-Román wrote: Hi Tim, It may be convenient to

[ccp4bb] disinfecting keyboards

2020-04-29 Thread Tim Gruene
Dear all, can you make suggestions for how to disinfect computer keyboards, and instrument panels? Our facility is going to reboot next week, with shifts so that people don't meet. The main interface will be the computer keyboards, as well as the door of our X-ray diffractometer and the mounting

Re: [ccp4bb] disinfecting keyboards

2020-04-29 Thread 00000c2488af9525-dmarc-request
Re: injecting disinfect[ing]ant[?] through the USB cable [port?].Dear TimI am intrigued, seriously.Best wishes.Jon CooperOn 29 Apr 2020 19:53, Tim Gruene wrote:Dear all, can you make suggestions for how to disinfect computer keyboards, and instrument panels? Our facility is going to reboot

Re: [ccp4bb] disinfecting keyboards

2020-04-29 Thread Ethan A Merritt
On Wednesday, 29 April 2020 11:53:32 PDT Tim Gruene wrote: > Dear all, > > can you make suggestions for how to disinfect computer keyboards, and > instrument panels? The consensus here is that the keyboards must have a cover that can be washed/disinfected. They are not [usually] that hard to

Re: [ccp4bb] disinfecting keyboards

2020-04-29 Thread Diana Tomchick
?100% ethanol or isopropanol work really well on the microscopes, I soak a Kimwipe and then clean the eyepieces and the knobs for changing magnification and focus, as well as the door handles, bench tops, etc. Diana ** Diana R. Tomchick

Re: [ccp4bb] disinfecting keyboards

2020-04-29 Thread Gianluca Santoni
ISO keyboards are bad. But why not just using disposable gloves to operate the instruments? On April 29, 2020 9:30:19 PM GMT+02:00, James Holton wrote: >Keyboards are cheap.  Why not everyone get their own? > >Then we can all stop fighting about whether the key should be >shaped like an "L" or

Re: [ccp4bb] disinfecting keyboards

2020-04-29 Thread Jurgen Bosch
You really just need two keyboards per computer, every user change, just add the used keyboards into the hutch, the rest should take care of itself then. You are at the source to successfully blast these little viruses Jürgen > On Apr 29, 2020, at 3:30 PM, James Holton wrote: > > Keyboards

Re: [ccp4bb] disinfecting keyboards

2020-04-29 Thread Eduardo Rodríguez-Román
Hi Tim, It may be convenient to install a UV light lamp in the room. Have you thought about that? I do not know if any of the equipment may suffer damage in the medium or long term due to the incidence of UV light. You must evaluate this. UV light is used in different microbiology laboratories

Re: [ccp4bb] disinfecting keyboards

2020-04-29 Thread Bernhard Rupp
>I do not know if any of the equipment may suffer damage in the medium or long >term due to the incidence of UV light. Hmm….everything made of cheap plastic….i.e. almost everything made in China…that must be the true conspiracy behind the virus! Cheers, BR On Wed, Apr 29, 2020 at

Re: [ccp4bb] disinfecting keyboards

2020-04-29 Thread Bernhard Rupp
>This email was not typed but spoken by Siri on my laptop. Outing yourself? https://www.youtube.com/watch?v=7-SVvtxHJGU HTH BR > On Apr 29, 2020, at 2:59 PM, Sravya Mounika Kantamneni > wrote: > > How about using keyboard guards and dissecting them as usual? > > Regards, > Sravya > >> On

Re: [ccp4bb] disinfecting keyboards

2020-04-29 Thread Matthew Bick
Even better - UV "inside the computer". Hasn't been done, but we're testing it and it looks promising. Matthew Bick On Wed, Apr 29, 2020 at 1:12 PM DUMAS Philippe (IGBMC) < p.du...@ibmc-cnrs.unistra.fr> wrote: > I got a good advice about it: inject WhiteHouse disinfectant right into > the cpu.

Re: [ccp4bb] disinfecting keyboards

2020-04-29 Thread Crissy Lynette Tarver
https://pdb101.rcsb.org/learn/videos/fighting-coronavirus-with-soap Crissy L Tarver Postdoctoral Researcher Department of Structural Biology Stanford University School of Medicine From: CCP4 bulletin board on behalf of Tim Gruene Sent: Wednesday, April 29,

Re: [ccp4bb] disinfecting keyboards

2020-04-29 Thread Tristan Croll
Posted semi-seriously (they look like they’d be awful to use, but maybe I’m being pessimistic): https://wiki.ezvid.com/best-virtual-keyboards. With a projection keyboard, all you have to worry about cleaning is the benchtop. > On 29 Apr 2020, at 21:38, Crissy Lynette Tarver wrote: > >

Re: [ccp4bb] disinfecting keyboards

2020-04-29 Thread David Briggs
Have you considered autoclaving the keyboards in between users? Or maybe autoclave the users? That'll work, right? -- Dr David C. Briggs Senior Laboratory Research Scientist Signalling and Structural Biology Lab The Francis Crick Institute London, UK == about.me/david_briggs

Re: [ccp4bb] disinfecting keyboards

2020-04-29 Thread Frank Von Delft
Make your users wear masks. Sent from tiny silly touch screen From: David Schuller Sent: Wednesday, 29 April 2020 21:03 To: CCP4BB@JISCMAIL.AC.UK Subject: Re: [ccp4bb] disinfecting keyboards If you are going that route, it would make sense to locate the UV lamps

Re: [ccp4bb] disinfecting keyboards

2020-04-29 Thread Lukasz Sobala
You can find tutorials for everything on YouTube, and one prominently featured >>tech tip<< uses a dishwasher on a selection of cheap to expensive keyboards. Interestingly, all keyboards worked after drying. Good luck, Lukasz On Wed, 29 Apr 2020, 22:12 DUMAS Philippe (IGBMC), <

Re: [ccp4bb] 2fofc maps from refmac twinned refinement - clarify?

2020-04-29 Thread Petrus Zwart
I am not quite sure how it is done in Refmac, but in phenix it works as follows - difference maps are gradient maps for a least squares target and they do not contain any amplitude contamination from twinning. - Fo type maps are computed either via classic detwinning (solving the linear

Re: [ccp4bb] disinfecting keyboards

2020-04-29 Thread DUMAS Philippe (IGBMC)
I got a good advice about it: inject WhiteHouse disinfectant right into the cpu. Good to repeat it a couple of times, but wear mask and gloves against possible Cotrump-16-20 last attacks ! Hope it will be helpful. Philippe Dumas (#SupportFauci) - Mail original - De: "Jurgen Bosch" À:

[ccp4bb] EMBL Online Course - Solution Scattering from Biological Macromolecules

2020-04-29 Thread Clement Blanchet
Dear Colleagues, the EMBL SAXS group is offering a free online lecture course on Solution Scattering from Biological Macromolecules. Starting from Tuesday, May 5th, members of our group will give a total of 8 live webinars at *9:20 AM (CEST) on Tuesdays and Thursdays* (excluding public

Re: [ccp4bb] disinfecting keyboards

2020-04-29 Thread Jurgen Bosch
Somehow this reminds me of the scene of Scotty talking into the mouse when he is instructed to use the keyboard to interact with the computer. How is voice recognition these days on Linux? This email was not typed but spoken by Siri on my laptop. Jürgen > On Apr 29, 2020, at 2:59 PM, Sravya