Dear ccp4bb Subscribers,


Would you like to use your expertise to combat important problems affecting
public health?  Are you interested in combining your skills in structural
biology with quantitative genetic approaches?   Do you enjoy working in a
collaborative, intellectually stimulating environment, situated in one of
the most exciting (and beautiful) cities in the world?


The Rosenberg lab, located at University of California - San Francisco
(UCSF) and affiliated with the Chan-Zuckerberg Biohub, has an NIH funded
position for a postdoctoral scholar to continue our work characterizing the
structural biology of host-pathogen interactions.  You will have exciting
opportunities to combine your structural findings with functional
characterization using microbial genetics.  In recent work, we have used a
variety of structural techniques to characterize bacterial virulence
systems (see for example, PMID: 31886769, PMID: 28252385, or PMID:
25865481).  We have also developed novel genetic tools that can be used to
study how pathogens interact with their hosts (PMID: 30617347, PMID:
31481541, or PMID: 31073154).


We are looking for a Ph.D. candidate or recipient trained in electron
microscopy or x-ray crystallography and with an interest in expanding their
structural tool kit.  Our facilities at UCSF include access to a Talos
Arctica Cryo-TEM for screening and a Krios with a K3 bioquantum for data
collection, as well as several other instruments for negative stain and
additional data collection.  We also have new funding for the installation
of a Cryo-FIB and a cryo-fluorescence microscope to facilitate CryoCLEM.
Additionally, there is a state-of-the-art, automated facility for protein
crystal growth, and essentially unlimited access to synchrotron time at
ALS. Many shared instruments are available for biophysical characterization
of proteins.


If you are interested, please contact Laura Wise (laura.w...@ucsf.edu) with
a cover letter and a CV describing your work and we will be in touch!
Please submit your application before April 1'st for full consideration,
though the start date is negotiable.


The University of California is an *Equal Opportunity*/Affirmative Action
*Employer*. All qualified applicants will receive consideration for
*employment* without regard to race, color, religion, sex, sexual
orientation, gender identity, national origin, disability, age or protected
veteran status.


Looking forward to hearing from you soon,


Oren

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Oren Rosenberg
Associate Professor of Medicine

University of California, San Francisco

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