Postdoctoral Position: molecular structural biology of mechano-signalling cascades in muscle
** This position would suit an excellent candidate with ambition to transition to a team leader position ** We seek a highly motivated postdoctoral researcher to join our laboratory at the Department of Biology, University of Konstanz, Germany. Our laboratory studies the molecular mechanisms underpinning the architecture, stress response, adaptation and disease process of striated muscle. The successful applicant will work on profiling the cellular pathways that mediate the communication of the contractile sarcomere with other cellular organelles in function of mechanical activity. The work will involve the identification of new pathway components and the development of molecular tools to test mechanistic hypotheses both in vitro and in vivo. We apply an integrative approach to structural biology that combines a rich variety of biochemical, biophysical, computational and structural methodologies, with emphasis on X-ray crystallography. The work benefits from access to excellent experimental facilities and a highly interdisciplinary collaborative environment. The position is available for 3 years in the first instance. Qualifications Applicants should hold a Ph.D. in biophysics, biochemistry or related discipline and have a strong background in protein expression/purification, biophysical or biochemical characterization of protein samples and macromolecular X-ray crystallography. Experience in nanobody affinity binders, analysis of macromolecular complexes and/or cellular signalling will be of distinct advantage. Good command of written and spoken English, the ability to work in a team, and good communication and organizational skills are required. A publication record including first author manuscripts is expected. Application Applications should contain the following documents in PDF format: 1. Applicant's CV 2. Copies of original degree transcripts displaying marks obtained 2. A statement on how the applicant’s profile matches the position 3. Contact details of two referees Informal enquiries and application materials should be submitted by email to: olga.may...@uni-konstanz.de =================================== Prof. Olga Mayans Biophysics and Structural Biology Dept of Biology University of Konstanz D-78457 Konstanz, Germany Tel: +49 7531 88-2212 ######################################################################## To unsubscribe from the CCP4BB list, click the following link: https://www.jiscmail.ac.uk/cgi-bin/WA-JISC.exe?SUBED1=CCP4BB&A=1 This message was issued to members of www.jiscmail.ac.uk/CCP4BB, a mailing list hosted by www.jiscmail.ac.uk, terms & conditions are available at https://www.jiscmail.ac.uk/policyandsecurity/
