I received this from a listserve for the Project for Monitoring Emerging 
Diseases (ProMED). It contains useful information related to the epidemic of 
avian flu in wild birds and poultry and the low risk of infection in humans in 
Colorado. I’ve observed several dead pelicans and gulls in Larimer County in 
recent days. 

>  From: ProMED <pro...@isid.org> 
> 
> Sent: Friday, April 29, 2022 3:56 PM
> To: Komar, Nick (CDC/DDID/NCEZID/DVBD) <n...@cdc.gov>
> Subject: PRO/AH/EDR> Avian influenza, human (14): Americas (USA) H5N1
> 
>  
> 
> AVIAN INFLUENZA, HUMAN (14): AMERICAS (USA) H5N1
> ************************************************
> A ProMED-mail post
> http://www.promedmail.org
> ProMED-mail is a program of the
> International Society for Infectious Diseases
> http://www.isid.org
> 
> Date: Thu 28 Apr 2022 21:46 EDT 
> Source: KKTV [edited] 
> https://www.kktv.com/2022/04/29/colorado-man-tests-positive-h5-bird-flu-1st-human-case-us-cdc-reports-public-health-risk-assessment-remains-low/
>  
> 
> 
> The 1st human case associated with the H5 bird flu in the United
> States was detected in a Colorado man. The Centers for Disease Control
> [and Prevention] (CDC) shared information on the case with the public
> on Thursday [28 Apr 2022], adding the "public health risk assessment
> remains low." The CDC adds people who have job-related or recreational
> exposures to infected birds are at a higher risk of infection and
> should take appropriate precautions. 
> 
> The CDC has been monitoring people exposed to H5N1 virus-infected
> birds since the outbreaks were first detected in wild birds and
> poultry in late 2021. To date [28 Apr 2022], H5N1 viruses have been
> found in US commercial and backyard birds in 29 states and in wild
> birds in 34 states. CDC has tracked the health of more than 2500
> people with exposures to H5N1 virus-infected birds, and this is the
> only case that has been found to date. Other people involved in the
> culling operation in Colorado have tested negative for H5 virus
> infection, but they are being tested again out of an abundance of
> caution. Several wild birds have tested positive for the virus in
> Colorado. 
> 
> "This is the 2nd human case associated with this specific group of H5
> viruses that are currently predominant, and the 1st case in the United
> States," part of a news release from the CDC reads. "The 1st case
> internationally occurred in December 2021 in the United Kingdom in a
> person who did not have any symptoms and who raised birds that became
> infected with H5N1 virus. More than 880 human infections with earlier
> H5N1 viruses have been reported since 2003 worldwide, however, the
> predominant H5N1 viruses now circulating among birds globally are
> different from earlier H5N1 viruses." 
> 
> The 40-year-old man who tested positive was isolating as of Thursday
> [28 Apr 2022], as he was only experiencing fatigue. The Colorado
> Department of Public Health and Environment (CDPHE) is reporting the
> positive result is due to direct exposure to infected poultry at a
> commercial farm in Montrose County. The person, who is an inmate at a
> state correctional facility in Delta County, was working with poultry
> as part of a pre-release employment program where participants have
> the opportunity to work for private employers and be paid a prevailing
> wage. The affected flock has been euthanized and disposed of under the
> guidance of the USDA and CDA. All members of the response team,
> including other inmate workers, were provided personal protective
> equipment while working on the farm. 
> 
> "We want to reassure Coloradans that the risk to them is low," said
> Dr. Rachel Herlihy, state epidemiologist, Colorado Department of
> Public Health and Environment. "I am grateful for the seamless
> collaboration between CDC, Department of Corrections, Department of
> Agriculture, and CDPHE, as we continue to monitor this virus and
> protect all Coloradans." CDPHE adds human infections of the H5 viruses
> are rare. 
> 
> [Byline: Tony Keith] 
> 
> -- 
> Communicated by: 
> Ryan McGinnis 
> r...@digicana.com
> 
> [The above report mentions the 1st human case of avian influenza
> A/H5N1 in the United States. The 1st human case with this specific
> virus group was reported in December 2021 in the UK. The predominant
> H5N1 viruses now circulating among birds globally are different from
> earlier H5N1 viruses. The case had a history of direct exposure to
> poultry. 
> 
> Typically human cases of zoonotic/avian influenza viruses are preceded
> by outbreaks in poultry; there have been numerous outbreaks of avian
> influenza A/H5N1 in USA and Canada, with loss of over 31 million birds
> in the US commercial poultry industry in 2022
> (https://www.wattagnet.com/blogs/27-agrifood-angle/post/44969-breaking-down-us-avian-flu-cases-by-flock-type).
>  
> 
> Mod.TG comments: "As one looks through the postings of the rampage of
> avian influenza, it becomes abundantly clear this virus is sweeping
> through the country like a grim reaper. The virus is merciless to both
> domestic birds and some species of wild birds in the USA and Canada. 
> 
> "Destroyed bird counts are increasingly going up. This means live bird
> counts are going down, affecting eggs and meat birds and decreasing
> wildlife. As dead bird counts mount, the cost is rising in the grocery
> stores, and in the cost of replacement birds" (from Avian influenza
> (106): Americas (Canada, USA) mixed flocks, HPAI H5N1
> http://promedmail.org/post/20220429.8702913). 
> 
> "Because of the possible threat bird flu viruses pose to human health,
> [it is important to conduct] research to learn more about these
> viruses, for example, where they spread, how they spread, and what
> kinds of disease they cause. This includes antigenic characterization,
> antiviral resistance, genetic characterization, serology and
> assessment of bird flu viruses' ability to cause disease and spread in
> animal models. This information, coupled with disease surveillance
> information, can help scientists better understand the risk these
> viruses pose to human health"
> (https://www.cdc.gov/flu/avianflu/risk-assessment-research.html). 
> 
> Using the WHO animal-human interface review dated 14 Apr 2022, we
> understand that most human cases were sporadic infections exposed to
> A(H5) viruses through contact with infected poultry or contaminated
> environments, including live poultry markets
> (https://www.who.int/publications/m/item/influenza-at-the-human-animal-interface-summary-and-assessment-7-april-2021).
> Since the viruses continue to be detected in animals and related
> environments, further human cases can be expected. 
> 
> Even though small clusters of A(H5) virus infections have been
> reported previously, including those involving healthcare workers,
> current epidemiological and virological evidence suggests that
> influenza A(H5) viruses have not acquired the ability of sustained
> transmission among humans; thus, the likelihood is low. 
> 
> Strong surveillance is needed at the health facility level for cases
> presenting with the respiratory illness and history of handling
> poultry. With the COVID-19 pandemic far from over, this remains a
> challenge and requires continued advocacy. Human infections with
> microorganisms of animal origin must be suspected among the population
> when human-animal interfacing is common. Surveillance for influenza
> viruses both in poultry/animal and human population, together with
> early laboratory confirmation of such viruses to detect antigenic
> drift or shift conferring human-to-human transmission of these
> viruses, is critical for a timely response to avoid any large-scale
> public health event. The Avian Influenza Weekly Update issued by WHO
> for Western Pacific Region is available at
> https://www.who.int/docs/default-source/wpro---documents/emergency/surveillance/avian-influenza/ai_20220422.pdf.
> - Mod.UBA
> 
> ProMED map:
> United States: https://promedmail.org/promed-post?place=8702920,106]
> 
> [See Also:
> Avian influenza (106): Americas (Canada, USA) mixed flocks, HPAI H5N1
> http://promedmail.org/post/20220429.8702913 
> Avian influenza (103): Americas (Canada, USA) mixed flocks, HPAI H5N1
> http://promedmail.org/post/20220427.8702870 
> Avian influenza (102): Americas (USA) wild birds, HPAI H5N1
> http://promedmail.org/post/20220425.8702840 
> Avian influenza (100): Americas (Canada, USA) poultry, mixed flocks,
> HPAI H5N1 http://promedmail.org/post/20220422.8702765 
> Avian influenza (98): Americas (Canada, USA) poultry, mixed flocks,
> HPAI H5N1 http://promedmail.org/post/20220420.8702706 
> Avian influenza (97): Americas (USA) wild birds, die-off, susp
> http://promedmail.org/post/20220418.8702687 
> Avian influenza (96): Americas (Canada, USA) poultry, mixed flocks,
> HPAI H5N1 http://promedmail.org/post/20220416.8702664 
> Avian influenza (92): Americas (Canada, USA) wild bird, HPAI H5N1
> http://promedmail.org/post/20220413.8702586 
> Avian influenza (90): Americas (Canada, USA) poultry, mixed flocks,
> HPAI H5N1 http://promedmail.org/post/20220413.8702577 
> Avian influenza (88): Americas (Canada, USA) poultry, mixed flocks,
> HPAI H5N1 http://promedmail.org/post/20220411.8702536 
> Avian influenza (87): Americas (USA) poultry, mixed flocks, HPAI H5N1
> http://promedmail.org/post/20220409.8702501 
> Avian influenza (86): Americas (Canada) poultry, mixed flocks, HPAI
> H5N1 http://promedmail.org/post/20220409.8702499 
> Avian influenza (84): Americas (Canada, USA) poultry, mixed flocks,
> HPAI H5N1 http://promedmail.org/post/20220405.8702425 
> Avian influenza (83): Americas (Canada, USA) mixed flocks, HPAI H5N1
> http://promedmail.org/post/20220403.8702369 
> Avian influenza (80): Americas (Canada, USA) poultry, mixed flocks,
> HPAI H5N1 
> Avian influenza (76): Americas (USA) poultry, HPAI H5N1
> http://promedmail.org/post/20220326.8702236 
> Avian influenza (70): Americas (USA) wild bird, HPAI H5N1
> http://promedmail.org/post/20220320.8702088 
> Avian influenza (68): Americas (USA) mixed flocks, HPAI
> http://promedmail.org/post/20220316.8702021 
> Avian influenza (65): Americas (Canada, USA) wild bird, HPAI H5N1
> http://promedmail.org/post/20220311.8701931 
> Avian influenza (62): Americas (USA) poultry
> http://promedmail.org/post/20220308.8701868 
> Avian influenza (53): Americas (USA) wild bird, poultry, HPAI H5N1
> http://promedmail.org/post/20220225.8701648 
> Avian influenza (50): Americas (Canada, USA) poultry, mixed flock,
> wild bird, HPAI http://promedmail.org/post/20220221.8701557 
> Avian influenza (40): Americas (USA) wild bird, HPAI H5N1
> http://promedmail.org/post/20220210.8701387 
> Avian influenza (30): Americas (USA) wild bird
> http://promedmail.org/post/20220201.8701178 
> Avian influenza (22): Americas (USA) wild bird, HPAI H5N1 Archive
> Number: http://promedmail.org/post/20220120.8700990 
> Avian influenza (19): Americas (USA) wild bird, HPAI H5, OIE
> http://promedmail.org/post/20220117.8700932 
> 2020 
> ---- 
> Avian influenza (39): USA (SC) poultry, HPAI H7N3
> http://promedmail.org/post/20200410.7206731 
> 2017 
> ---- 
> Avian influenza (79): USA (TN): poultry, HPAI H7N9
> http://promedmail.org/post/20170317.4908223 
> Avian influenza (78): USA poultry, (AL) H7, (TN) H7N9, both LPAI
> http://promedmail.org/post/20170317.4906690 
> Avian influenza (71): USA (WI) turkey, HPAI H7N9
> http://promedmail.org/post/20170311.4893871 
> Avian influenza (69): USA (TN) poultry, HPAI H7N9
> http://promedmail.org/post/20170309.4888517 
> Avian influenza (67): USA (TN) poultry, HPAI H7, OIE
> http://promedmail.org/post/20170307.4883078 
> Avian influenza (66): USA (TN) poultry, HPAI, H7
> http://promedmail.org/post/20170305.4881365 
> 2016 
> ---- 
> Avian influenza (15): USA (IN) poultry, HPAI & LPAI H7N8
> http://promedmail.org/post/20160121.3953508 
> Avian influenza (11): USA (IN) poultry, HPAI/LPAI H7N8
> http://promedmail.org/post/20160120.3950429 
> Avian influenza (08): USA (IN) poultry, HPAI revised to LPAI H7N8,
> update http://promedmail.org/post/20160118.3944747 
> 2015 
> ---- 
> Avian influenza (164): USA (GA) HPAI H5N2, poultry, proactive
> prevention http://promedmail.org/post/20150620.3452030 
> Avian influenza (151): USA (MN, IA) HPAI H5N2, poultry
> http://promedmail.org/post/20150606.3414670 
> Avian influenza (120): USA, HPAI H5N2, poultry, turkey
> http://promedmail.org/post/20150510.3352747 
> Avian influenza (80): USA, HPAI H5N2, turkey, poultry
> http://promedmail.org/post/20150415.3298419 
> Avian influenza (74): USA (MN, ND) HPAI H5N2, turkey
> http://promedmail.org/post/20150412.3292191 
> Avian influenza (59): USA (MN): turkey, H5N2
> http://promedmail.org/post/20150329.326408]
> .................................................uba/tg/rd
> 
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