..............................................................

>From the New Paradigms Project [Not Necessarily Endorsed]:

From: Alex Constantine <[EMAIL PROTECTED]>
To: Lloyd <[EMAIL PROTECTED]>
Subject: FW: Aspartame Toxicity 6.2.00: Trocho 6.26.98
Date: Tuesday, June 20, 2000 4:50 PM


----------
From: Rich Murray <[EMAIL PROTECTED]>
Date: Tue, 20 Jun 2000 08:44:24 -0600
To: [EMAIL PROTECTED], [EMAIL PROTECTED]
Subject: Aspartame Toxicity 6.2.00: Trocho 6.26.98


Aspartame Toxicity  6.2.00: Trocho 6.26.98

Rich Murray   Room For All
1943 Otowi Drive, Santa Fe, New Mexico 87505
505-986-9103  505-920-6130 cell   [EMAIL PROTECTED]
[B.A., M.I.T. 1964, M.A., Boston U. 1967: a layman committed to
facilitating civil debate on aspartame toxicity]

Aspartame (NutraSweet, Equal, Canderel, Benevia) is reported by many
scientific studies and case histories to be toxic: headaches, all kinds
of body and joint pain (or burning, tingling, tremors, twitching,
spasms, cramps, or numbness);  "mind fog", "feel unreal", poor memory,
confusion, anxiety, irritability, depression, mania, insomnia,
dizziness, slurred speech, ringing in ears, sexual problems, nausea,
seizures, poor vision, hearing, or taste; fever, fatigue;  red face,
itching, rashes, burning eyes or throat, dry mouth or eyes, mouth
sores; hair loss;  obesity, bloating, edema, poor or excessive hunger
or thirst, anorexia; coldness; diarrhea or constipation; breathing
problems; racing heart, high blood pressure, erratic blood sugar
levels; birth defects; brain cancers.

Users who quit often experience much immediate healing, but some
symptoms may last for weeks. Heavy users may suffer weeks of painful
withdrawal symptoms.  Also avoid all forms of MSG (glutamate),
legally mislabeled as "hydrolyzed vegetable protein" or even
"natural flavoring".  Some versions of RC Diet Rite Cola use Splenda
(sucralose) and Acesulfame-K, far less hazardous than asp., but
so far available only in a few areas. It's fun to mix club soda with
juices. A long-used herbal sweetener, stevia, is entirely safe and
widely available.  A corrupt FDA has refused to attest its safety:
www.holisticmed.com/sweet/stv-alert.txt

Read all labels!-- aspartame is in almost all diet sodas; many drink
mixes, instant breakfasts, cereals, cake mixes, yogurts, puddings,
jellos, chewing gums, breath mints, candies, toothpastes, laxatives,
cough syrups, even vitamins and medicines. Absorption through the skin
in the mouth may be especially strong.

Three careful double-blind experimental studies prove aspartame
causes headaches:  Koehler SM et al, 1988, Headache, 28(1), 10-14.
Shirley Koehler, PhD  904-858-7651  [EMAIL PROTECTED]

Walton RG et al, 1993, Biological Psychiatry, 34(1), 13-17.
Prof. Ralph G. Walton  330-740-3621  [EMAIL PROTECTED]

Van Den Eeden SK et al, 1994, Neurology, 44, 1787-93.
Steven K. Van Den Eeden, PhD  550-450-2202  [EMAIL PROTECTED]

Woodrow C. Monte, Director, Food Science and Nutrition Laboratory
602-965-6938  Arizona State University, [EMAIL PROTECTED],
"Aspartame: Methanol and the Public Health," 1984,
J. Applied Nutrition, 36(1), 42-54 (62 references):
The methanol from 2 L of diet soda, 5.6 12-oz cans, 20 mg/can, is
112 mg, 10% of the asp. The EPA limit for water is 7.8 mg daily for
methanol (wood alcohol), a deadly cumulative poison.  Many users
drink 1-2 L daily.  The reported symptoms are entirely consistent
with chronic methanol toxicity.  (Fresh orange juice has 34 mg/L, but,
like all juices, has 16 times more ethanol, which strongly protects
against methanol.)  www.dorway.com/wmonte.txt

A radioactive tracer study proves that the methanol from a low dose of
of aspartame binds formaldehyde, a deadly cumulative poison, into
tissues: Trocho C et al, June 26 1998, Life Sci, 63(5), 337-349.
www.PRESIDIOTEX.COM/barcelona/index.html

Lennart Hardell, M.D., PhD, in 1999 reported in Sweden that both
cell phone use and heavy aspartame use correlate with increased
brain cancers:  www.medscape.com/MedGenMed/braintumors

Who pays the piper, calls the tune.  Ralph G. Walton, Prof. of
Clinical Psychology, Northeastern Ohio Universities, Youngstown,
OH 44501, 330-740-3621  [EMAIL PROTECTED] , in an unpublished
66-page study (1998), listed 166 studies about asp. and health. All
74 studies funded by the industry were favorable, whereas 84 of the 92
non-industry studies identified a problem. Moreover, many industry
studies were published repeatedly with slight changes, from 2 to 6
times each, violating scientific ethics.  www.dorway.com/peerrev.html
Al Raetz has justly criticized bias in both sides of the debate:
www.aspartametruth.freeservers.com/personal.html

Asp. Victims Support Group Home Page www.presidiotex.com/aspartame/

Aspartame Toxicity Information Center    Mark D. Gold
www.HolisticMed.com/aspartame  603-225-2100
"Scientific Abuse in Aspartame Research"
www.holisticmed.com/aspartame/abuse/methanol.html
[EMAIL PROTECTED]  12 East Side Drive #2-18 Concord, NH 03301

Mission-Possible-USA Betty Martini  770-242-2599
www.dorway.com  [EMAIL PROTECTED]

Aspartame Consumer Safety Network 800-969-6050  214-352-4268
Mary Nash Stoddard [EMAIL PROTECTED] "The Deadly Deception"
http://web2.airmail.net/marystod/index.html

[EMAIL PROTECTED]  United Kingdom Mission Possible Intern.
63 Downlands Road  DEVIZES  SN10 5EF  Tel: 01380 728059
www.connectotel.com/missionpossible/

H.J. Roberts, M.D.  [EMAIL PROTECTED]   800-814-9800
Sunshine Sentinel Press http://members.icanect.net/~sunpress/index.htm
6708 Pamela Lane  West Palm Beach, Florida 33405
561-588-7628  561-547-8008 fax     See detailed 5-page review:
"Aspartame (NutraSweet) Addiction"  Townsend Letters  Jan 2000,
www.dorway.com/tldaddic.html

Search medical reports:  www.ncbi.nlm.nih.gov/PubMed

"The Dangers of Aspartame" discussion forum with many long reports with
references:  www.bevnet.com/bevboard/

The eminent British journal: The Lancet Interactive Discussion Group:
Aspartame Toxicity: fact or fiction?  www.thelancet.com/

For a searchable archive: www.eScribe.com/health/aspartameNM/  or
www.eGroups.com/community/aspartameNM/

www.truthinlabeling.org/  Truth in Labeling Campaign [MSG]
Adrienne and Jack Samuels  P.O. Box 2532   Darien, Illinois 60561
858-481-9333  [EMAIL PROTECTED]  "The Toxicity/Safety of Processed
Free Glutamic Acid (MSG): A Study in Suppression of Information."

Health Press   [EMAIL PROTECTED]   505-474-0303
www.healthpress.com/in-bad-taste.html
George R. Schwartz, M.D.  [EMAIL PROTECTED]
"In Bad Taste: The MSG Symptom Complex"
www.healingresearch.org/  Healing Research Institute
*******************************************************

April 21, 1999  Richard T. Murray, M.A.  [EMAIL PROTECTED]
Here is research in 1998 at a very low level of aspartame ingestion,
10 mg/kg, for rats, which have a much greater tolerance for aspartame
than humans. The same level for humans would be about 1 or 2 mg/kg.
Many headache studies in humans used doses of about 30 mg/kg daily.
A daily dose of 2100mg aspartame, about 4 L diet soda, used in many
experimental tests on humans, supplies 210mg methanol into the body.
Many cases report a typical serious symptom syndrome at this level.

This report shows that aspartame causes binding of methanol's product,
formaldehyde, a potent, cumulative toxin, into tissues.

Life Sci June 26 1998; 63(5): 337-49 From PubMed
Formaldehyde derived from dietary aspartame binds to tissue
components in vivo.
Trocho C, Pardo R, Rafecas I, Virgili J, Remesar X,
Fernandez-Lopez JA, Alemany M, Departament de Bioquimica i
Biologia Molecular, Facultat de Biologia, Universitat de Barcelona,
Spain.

Sra. Carme Trocho, Sra. Rosario Pardo, Dra. Immaculada Rafecas,
Sr. Jordi Virgili, X. Remesar, Dr. Jose Antonio Fernandez-Lopez,
Dr. Marià Alemany Fac. Biologia Tel.:
(93)4021521, FAX: (93)4021559
[EMAIL PROTECTED]   [EMAIL PROTECTED]
[EMAIL PROTECTED]   [EMAIL PROTECTED]

This report is available in full at:
http://www.PRESIDIOTEX.COM/barcelona/index.html

Abstract:
Adult male rats were given an oral dose of 10 mg/kg aspartame,
14C-labelled in the methanol carbon. At timed intervals of up to 6
hours, the radioactivity in plasma and several organs was investigated.
Most of the radioactivity found (>98% in plasma, >75% in liver) was
bound to protein. Label present in liver, plasma and kidney was in the
range of 1-2% of total radioactivity administered per g or mL, changing
little with time. Other organs (brown and white adipose tissues,
muscle, brain, cornea and retina) contained levels of label in the
range of 1/12th to 1/10th of that of liver. In all, the rat retained,
6 hours after administration, about 5% of the label, half of it in the
liver. The specific radioactivity of tissue protein, RNA and DNA was
quite uniform. The protein label was concentrated in amino acids,
different from methionine, and largely coincident with the result of
protein exposure to labelled formaldehyde. DNA radioactivity was
essentially in a single different adduct base, different from the
normal bases present in DNA. The nature of the tissue label
accumulated was, thus, a direct consequence of formaldehyde binding
to tissue structures. The administration of labelled aspartame to a
group of cirrhotic rats resulted in comparable label retention by
tissue components, which suggests that liver function(or its defect)
has little effect on formaldehyde formation from aspartame and binding
to biological components. The chronic treatment of a series of rats
with 200 mg/kg of non-labelled aspartame during 10 days results in
the accumulation of even more label when given the radioactive bolus,
suggesting that the amount of formaldehyde adducts coming from
aspartame in tissue proteins and nucleic acids may be cumulative.
It is concluded that aspartame consumption may constitute a hazard
because of its contribution to the formation of formaldehyde adducts.
PMID: 9714421, UI: 98378223

Mark D. Gold has an excellent, detailed analysis, "Scientific Abuse in
Methanol / Formaldehyde Research Related to Aspartame" at:

http://www.holisticmed.com/aspartame/abuse/methanol.html#discussion

In short, biochemical evidence exists to motivate us to seriously and
respectfully consider anecdotal evidence of aspartame toxicity.

Mark D. Gold gives another detailed review, "Scientific Abuse in
Seizure Research Related to Aspartame", at:

http://www.holisticmed.com/aspartame/abuse/seizures.html .

"If the seizures from aspartame are caused by the combination of
methanol/formaldehyde and the excitotoxic amino acid from aspartame,
as I believe may be the case, it is important to note that methanol is
10 times more acutely toxic in humans than in rodents (Roe 1982), and
it takes five times more excitotoxins given to rodents to simulate
human ingestion (Olney 1988, Stegink 1979, page 90)."
***************************************************************










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