-Caveat Lector-

WHO calls urgent meeting over possible link between cancer,
starchy foods

By CLARE NULLIS, Associated Press

GENEVA (June 24, 2002 12:35 p.m. EDT) - Alarmed about new
studies indicating that potato chips, french fries and certain types
of bread contain a substance that may cause cancer, the World
Health Organization has convened an emergency meeting to
evaluate the research and decide what action to take.

The three-day meeting, which opens Tuesday, follows the
publication in April of a Swedish study that some starch-based
foods cooked at high temperatures contained acrylamide.

Acrylamide, used to produce plastics and dyes and to purify
drinking water, has been shown to be carcinogenic in animal
experiments and is suspected of causing cancer among people
exposed to high levels for long periods. Although traces of it have
been found in water, its possible presence at high levels in basic
foods came as a shock.

"If what we know from water and animal experiments is true, it
could be a very significant source of cancer in humans," said
Jorgen Schlundt, coordinator of WHO's food safety division. "It is
not just another food scare," he said.

Such was the level of WHO concern that it organized the
gathering of 25 international experts within two months of the
publication of the Swedish study. According to Schlundt, this set
a "world record" for the U.N. health agency, which usually takes
about one year to organize meetings of experts to review
scientific data.

Although much is known about acrylamide and its effects in
animals, there is far less information about its effects on humans.
After the study was released in April, some U.S. scientists urged
consumers to be patient in awaiting more investigation.

"I think we need to step back a little bit and wait for greater
discussion of the issue and see the findings presented in more
detail," said Carl Winter, a toxicologist at the University of
California at Davis. "The most important thing is not the
presence or absence of any type of ingredient, but how much is
there."

Mary Ellen Camire, a food scientist and nutritionist at the
University of Maine, was skeptical about any link to cancer and
said it was important to remember that whole-grain bread and
potatoes contain a lot of important nutrients.

"The risk-to-benefit ratio is hard to estimate," she said at the
time. "We eat a lot of strange chemicals, but that's life. You just
have to get a balance."

Schlundt said subsequent studies in Norway, Britain and
Switzerland basically backed up the findings of Sweden's
National Food Administration.

"It is not a case of a batch of wrong results from scientists," he
said. "Everybody who has any expertise understands this is a
potential threat."

In voicing misgivings about the validity of the Swedish results,
which were based on 100 foods, scientists noted that they were
released at a government news conference rather than passing
through normal peer review procedures in a scientific journal.

The Swedish researchers said that "fried, oven-baked and deep-
fried potato and cereal products may contain high levels of
acrylamide." The same results were not found in boiled products.


Swedish government scientists estimated it could be
responsible for several hundred of the 45,000 cancer cases in
the country each year, based on experiments in which rats were
fed fried food.

Schlundt said the type of cancers provoked by acrylamide in
animals were not just limited to the digestive tract, but also
included the mammary and testicular glands, and skin. But he
stressed there was no evidence to suggest this could apply to
humans.

He said it was premature to predict whether the meeting would
urge dietary changes, or recommend further studies in specific
areas.

Regardless of the acrylamide fears, there is basic consensus
that people should limit consumption of fried and fatty foods if
they want a healthy diet. But it would prove more difficult to issue
advice concerning bread - and only certain types are so far
implicated - given its importance in many national diets.

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