Package: wnpp Severity: wishlist Subject: ITP: r-bioc-pfamanalyzer -- GNU R identification of domain isotypes in pfam data Package: wnpp Owner: Andreas Tille <ti...@debian.org> Severity: wishlist
* Package name : r-bioc-pfamanalyzer Version : 1.0.1 Upstream Author : Kristoffer Vitting-Seerup * URL : https://bioconductor.org/packages/pfamAnalyzeR/ * License : MIT Programming Lang: GNU R Description : GNU R identification of domain isotypes in pfam data Protein domains is one of the most import annoation of proteins we have with the Pfam database/tool being (by far) the most used tool. This R package enables the user to read the pfam prediction from both webserver and stand-alone runs into R. We have recently shown most human protein domains exist as multiple distinct variants termed domain isotypes. Different domain isotypes are used in a cell, tissue, and disease- specific manner. Accordingly, we find that domain isotypes, compared to each other, modulate, or abolish the functionality of a protein domain. This R package enables the identification and classification of such domain isotypes from Pfam data. Remark: This package is maintained by Debian R Packages Maintainers at https://salsa.debian.org/r-pkg-team/r-bioc-pfamanalyzer