The National Institute for Mathematical and Biological Synthesis (NIMBioS) and Department of Biochemistry & Cellular and Molecular Biology at the University of Tennessee, Knoxville, are currently accepting applications for a three-year postdoctoral fellowship in computational biology with an interest in using systems approaches to understand complex biological processes in cell biology, cancer biology, immunology or developmental biology. While the applicant must propose an independent research project as part of the application, he/she will be expected to work closely with Dr. Tian Hong, Department of Biochemistry & Cellular and Molecular Biology.

An applicant may propose to use modeling, simulation, or analysis to produce useful biological information or concepts that current theories cannot provide. The proposed study should address biological problems involving dynamics and complexity of gene regulatory networks (GRNs) and/or the interplay between the GRNs and networks at the cellular level. Examples of the biological topics include, but are not limited to: • Cell cycle progression, cellular senescence, cell differentiation and death.
•    Plasticity of cells during development or cancer progression.
•    Cancer metastasis and dormancy.
• Dynamical response of immune system (including response to viral infection).
•    Development of immune cells.
•    Embryonic development.

Examples of the proposed computational methods include, but are not limited to: • Processing of omics data for dynamical modeling (e.g., genomic, transcriptomic, proteomic data). • Integration of multiscale data for dynamical modeling (e.g. transcriptomic, epigenomic, subcellular, cellular data). • Ordinary Differential Equation (ODE), Partial Differential Equation (PDE), and stochastic methods.
•    Multiscale modeling.
•    Parameter optimization.
• Analysis using bifurcation theory, landscape theory, and statistical methods.

*Support: *annual stipend of $51,000 and full University of Tennessee employee fringe benefits.

*Deadline: *Applications will be considered beginning April 2, 2017, continuing until the position is filled. Letters of recommendation should be submitted at the time of application.

*How to apply:* For more detail on the position and application guidelines, see http://www.nimbios.org/positions/.

For more information, contact NIMBioS Associate Director Dr. Brian O’Meara (bome...@utk.edu) or Dr. Tian Hong, Department of Biochemistry & Cellular and Molecular Biology (hongt...@utk.edu).



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/////Catherine Crawley, Ph.D. /
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