Re: [Felvtalk] Michael's last hope

[Terri Knight]

So my last email I sent a few days ago didn't seem to go through as it
needed to be moderated due to its size. I attached a pic of the blood test
results which clearly the system didn't like. This was my email:

Update.

So Michael was first put on Epo a few weeks ago due to the suggestions of
specialists that my vet contacted, he was not on it for long as the vet
could see it was not working. I then organized to get Winstrol for him, he
started it on 1 February but due to his blood count being super low he had
to have a second transfusion on 3 February to give the Winstrol a chance to
work. He is still on Doxy as far as I know and cortisone. He visited the
vet yesterday (14 Feb) with this update: his red blood cells are still
dropping, but his platelets are up and the vet said he had a bit more
colour in his mouth and tongue, he has lost a bit more weight and was
running a slight temperature so his medrol (not sure what that is) was
upped for 3 days, back to the vet on 17 Feb. So kind of mixed results but
still not looking good with the red blood cell production.

Unfortunately his latest test results shows a decline again, his red blood
cells went from 10.42% on Tuesday to 8.18% on Friday and there is nothing
more that can be done. At his current rate of decline he will reach
critical levels by Monday.

My parents and I (but mostly my parents since I'm on the other side of the
world) have to make a heartbreaking decision of when it's time for Mikey.
The vet says that when he reaches 6% he will be feeling terrible and to add
to this he has no more energy he just lies down in one spot all the time.

It is with a heavy heart and tears in my eyes that I have accept his fate
on top of being so far away from him.

Terri


On 22 Jan 2017 09:49, "Amani Oakley" <aoak...@oakleylegal.com> wrote:

I probably can’t attach the actual papers regarding the use of Stanazolol
(Winstrol) in osteoporosis, but the title of one of the papers is: *Stanozolol
in postmenopausal osteoporosis: therapeutic efficacy and possible
mechanisms of action.*



Here is the abstract of the paper:



*To assess the efficacy of the anabolic steroid stanozolol in the treatment
of osteoporosis, a 29-month double-blind study was performed with 23
treated and 23 control postmenopausal osteoporotic women. Drug efficacy was
assessed by serial determinations of total body calcium (TBC--total bone
mass) by neutron activation analysis, regional bone mass (RBM) by
single-photon absorptiometry, and by spinal roentgenograms. Total body
calcium increased 4.4% from baseline values (P less than 0.01) in the
treated group and remained unchanged in the control group; the difference
in the change in TBC between the treated and control groups was significant
(P less than 0.03). The effect of the drug on TBC persisted throughout the
29-month period. In contrast to TBC, measurements of RBM indicated no
significant differences between the treated and placebo groups, suggesting
a possible differential response to therapy at various skeletal sites. No
new spinal compression fractures were noted in the treated group (compared
with three new fractures in the control group). Assessment of serum and
urine values indicated a decrease in the level of urinary calcium and an
increase in the level of total urinary cyclic AMP in the treated group.
These changes were observed even though the level of serum iPTH was
significantly decreased during the study. An analysis of changes in bone
biopsy specimens revealed no significant differences between the treated
and control groups. Seventy-six percent of the treated subjects developed
SGOT elevations or other side effects from the stanozolol therapy; at no
time were these effects sufficiently severe to cause termination of
medication. The data suggest that long-term use of stanozolol increases the
net total bone mass above pretreatment levels.*



Amani



*From:* Felvtalk [mailto:felvtalk-boun...@felineleukemia.org] *On Behalf Of
*Terri Knight

*Sent:* January-21-17 1:12 PM
*To:* felvtalk@felineleukemia.org
*Subject:* Re: [Felvtalk] Michael's last hope



So an update.



I had to leave to start working in South Korea without my baby Mike, but I
left him in my parents capable hands. They have done a great job and
Michael's vet has been great with doing research and getting new options
from specialists.



I spoke to my vet about Amani's advice and he explained what those drugs
were for and what we were doing already, Michael is in South Africa so we
don't always get the same drugs or they have different names.



He was already on a cortisone injection which was a better option than the
tablet form (until he improves), he was more than willing to give Michael
the anabolic steroid but said that it doesn't actually do anything for
production of anything in the bone marrow it is to help with appetite, and
he was already on Baytril which was similar to Doxycycline but without the
common side effect of nausea. H

Re: [Felvtalk] Michael's last hope

[Terri Knight]

sign of his body
> regenerating. On the weekend he just seemed to improve so much, is appetite
> was back and he had interest in playing like his old self again, but
> Monday’s results did not reflect his behavior. His body was not
> regenerating and his counts had dropped slightly.
> >
> > My next step is blood tests and decisions on Friday. I am devastated and
> don’t know if there is anything else that we can do. If anyone can give any
> advice or suggestions I would really appreciate it. At the moment he is on
> Baytril and a nutritional tonic.
> >
> > Kind regards,
> > Terri Knight
> >
> > Sent from Mail for Windows 10
> >
> >
> > ___
> > Felvtalk mailing list
> > Felvtalk@felineleukemia.org
> > http://felineleukemia.org/mailman/listinfo/felvtalk_felineleukemia.org
> >
>
>
> ___
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Re: [Felvtalk] Felvtalk Digest, Vol 33, Issue 10

[Terri Knight]

Thanks everyone for the awesome response and advice. We will be back at the
vet on Friday for the next round of blood tests and I will discuss all
options and your advice with the vet.

I really am extremely grateful.

Terri

On 11 Jan 2017 23:46, "ROBERT CHAPEL"  wrote:

> Nancy
>
> In keeping with Amani's response...would be VERY interested to know if the
> cats ( with which you have had success) were ( are) FeLV+ per IFA or
> FeLV at all.
> Owners of FeLV Kitties can get desperate to find ANYTHING that might help
> their cats and can spend their way into oblivion with useless elixers that
> will leave them cash poor for the ( sometimes) more expensive drugs that
> stand a better chance of success Personally I can't imagine how Omega
> 3's are going to  have any appreciable effect on depressed RBC's.
> Aracept... as pointed out could be effective if the anemia is
> regenerativepossibly harmful if not ( cats can respond with antibodies
> to Epo and the like with antibodies that further depress their blood
> count
> If you have positive experience with the above would love to hear about
> it  even better if you have any reference papers to point us to
> regarding the successful use of Omega 3's in FeLV Kitties we would ALL, I
> am sure, be very interested as they are widely available and certainly
> reasonably priced ( generally)
> thanks...
>
>
> On Wed, Jan 11, 2017 at 01:00 PM, felvtalk-requ...@felineleukemia.org
> wrote:
>
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>> Today's Topics:
>>
>>1. Omega 3s (gidge...@aol.com)
>>2. Re: Omega 3s (Amani Oakley)
>>
>>
>> --
>>
>> Message: 1
>> Date: Wed, 11 Jan 2017 12:31:17 -0500
>> From: gidge...@aol.com
>> To: felvtalk@felineleukemia.org
>> Subject: [Felvtalk] Omega 3s
>> Message-ID: <1598e957a12-237d-5...@webprd-a66.mail.aol.com>
>> Content-Type: text/plain; charset="utf-8"
>>
>> I'm sure this won't be allowed, but I must try anyways as I cannot
>> express how important it is to put your cats on an omega 3 supplement.
>> Moxxor is 100% pure.  Green-lip mussel oil, grapeseed oil and kiwifruitseed
>> oil.  No preservatives, pesticides, GMOs, Mercury, PCBs, or excipients of
>> any kind.  My two FeLV cats are on Moxxor and knock on wood have been doing
>> well.  They also take the Rx Vitamins for Pets ~ Liquid Immuno.  All
>> natural.  For Moxxor, please please come join my FB page at
>> https://www.facebook.com/moxxorforabetterlife/to learn more about
>> this.  I swear by it for both me and for my two girls.
>>
>> Nancy
>> -- next part --
>> An HTML attachment was scrubbed...
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>>
>> Message: 2
>> Date: Wed, 11 Jan 2017 17:43:12 +
>> From: Amani Oakley To: "felvtalk@felineleukemia.org" Subject: Re:
>> [Felvtalk] Omega 3s
>> Message-ID:
>>
>> Content-Type: text/plain; charset="utf-8"
>>
>> Hi Nancy
>>
>> Were your cats in anemic crisis when you put them on the supplements, or
>> were they positive for FeLV but not in crisis? I am interested to know if
>> your supplements turned around severe non-regenerative anemia. I am sure I
>> am not telling you anything new when I indicate that the problem is that if
>> a cat is severely anemic and not producing his/her own red cells (low or
>> insufficient reticulocytes) then there is very little time to address the
>> crisis. Moreover, as I have posted before epogen, and other
>> erythropoietin-type mimics, act on the red cell precursors in the bone
>> marrow, signalling to them to produce more red cells. If the precursor
>> cells are damaged or killed by the virus, which they often are, and that is
>> why all three cell lines (red cells, white cells and platelets) are often
>> affected, then no amount of erythropoietin, ?yelling? at a dead precursor
>> cell, will get it to re-start red cell production. The only thing I have
>> found that has a chance to do that is the Winstrol, co
>>  upled with the Doxycycline. The Winstrol promotes the development of
>> bone marrow and has been found to be effective for conditions such as
>> osteoporosis. It promotes the growth and increased density of bone.
>>
>> Were you able to restart bone marrow red cell production with the
>> supplements you are referencing? I would be very interested to hear if that
>> is the case since we certainly need as many weapons in our