Re: [Felvtalk] Bone Marrow Testing for FELV positive Cat?
Thank you so much, again, Amani On Sep 19, 2019, at 8:13 PM, Amani Oakley mailto:aoak...@oakleylegal.com>> wrote: Wendy I was going to comment on that issue earlier, but I thought you had already gone ahead with the bone marrow testing. I am not sure there is any other treatment, regardless of the outcome of the testing. I personally agree with you that I probably would choose not to put my cat through bone marrow testing, when it really can’t affect the outcome. I am glad to hear that he is feeling better after the two transfusions. Use the Doxy-Pred-Winstrol combination now, and hopefully, your kitten’s haematocrit doesn’t end up falling after the temporary boost from the blood transfusion. The life span of a red blood cell is 120 days (at least in humans), and the blood transfusions will have red cells at different stages of their life spans, so you probably already know that the effect of the transfusions will probably only last 3 months or so. Hopefully by then the Winstrol would have kicked in to assist the bone marrow in producing red cells. Amani From: Felvtalk mailto:felvtalk-boun...@felineleukemia.org>> On Behalf Of Wendy Sent: September 19, 2019 10:41 PM To: felvtalk@felineleukemia.org<mailto:felvtalk@felineleukemia.org> Subject: [Felvtalk] Bone Marrow Testing for FELV positive Cat? Hello, Thank you all for your replies earlier today. Our cats’ red count is coming back after 2 blood transfusions, and we started doxy today. He is eating, drinking, purring, has much better energy, is back to talking, etc. We are awaiting results that we should have tomorrow morning on the test of his lymphocytes using blood that was drawn before the blood transfusions. If the test comes back showing that the lymphocytes contain cancer cells, then we have our answer. If the test comes back showing that the lymphocytes do not contain cancer cells, then it has been suggested that we do bone marrow testing asap tomorrow afternoon. My understanding is that the bone marrow test would likely either show that he has myelodysplasia or cancer in his bone marrow. My question is: Would the suggested treatment of Doxy + Pred + Winstrol change if we find out that our cat has myelodysplasia vs if he has cancer in his bone marrow? If the treatment is the same, then I question putting our cat at the risk of anesthesia, lowering his red count, infection, etc. The plan is to start our cat on Doxy + Pred + Winstrol tomorrow afternoon, and we are being told that if we want to test his bone marrow we need to do it tomorrow morning before we start giving him steroids. In addition, his chest x-ray today was clean, and his abdominal ultrasound showed a slightly enlarge spleen and either a few slightly enlarged lymph nodes or possibly a few small satellite spleens, all of which seems can be expected with the anemia and / or infection, and therefore was not cause for concern. Following are the background facts, which I also posted this morning: Our FELV positive neutered male cat approximately 1 and ½ years old has gotten very sick suddenly. He is a house cat, and he was neutered in May of 2019. A few days ago, he became lethargic and lost interest in eating. We had his blood drawn yesterday and he had iv fluids yesterday, and today we were told he needed a blood transfusion (or two) and more iv fluids, and then a bone marrow test tomorrow. We were told that the first blood transfusion today was not very effective because he got so many iv fluids at the same time, so now they are going to give him another transfusion. As background, we rescued him as a stray from Barbados in October 2018 when he was about 6 months old, and he has been healthy, active, happy and gaining weight, despite being FELV positive. Since October 2018, we cured him of giardia and bartonella henselae. On 12/31/2018, he tested positive for the ELISA and IFA, although his blood work was in normal ranges at that time. In 03/2019, we started giving him 1 t-cyte shot once per month, and we started giving him 1ml of interferon per days for 7 days on and then 7 days off, repeated. We have continued the interferon and t-cyte in this manner ever since 03/2019. Just yesterday, here are the results of his blood work: Tests ResultsRef. Range Total Protein 6.1 5.2- 8.8 g/dL Albumin 3.5 2.5- 3.9 g/dl Globulin 2.6 2.3- 5.3 g/dL A/G Ratio 1.30.35- 1.5 AST (SGOT) 106 (HIGH) 10-100 IU/L ALT (SGPT) 3910- 100 IU/L Alk Phosphatase406- 102 IU/L GGT 11- 10 IU/L Total Bilirubin 0.1
Re: [Felvtalk] Bone Marrow Testing for FELV positive Cat?
Wendy I was going to comment on that issue earlier, but I thought you had already gone ahead with the bone marrow testing. I am not sure there is any other treatment, regardless of the outcome of the testing. I personally agree with you that I probably would choose not to put my cat through bone marrow testing, when it really can't affect the outcome. I am glad to hear that he is feeling better after the two transfusions. Use the Doxy-Pred-Winstrol combination now, and hopefully, your kitten's haematocrit doesn't end up falling after the temporary boost from the blood transfusion. The life span of a red blood cell is 120 days (at least in humans), and the blood transfusions will have red cells at different stages of their life spans, so you probably already know that the effect of the transfusions will probably only last 3 months or so. Hopefully by then the Winstrol would have kicked in to assist the bone marrow in producing red cells. Amani From: Felvtalk On Behalf Of Wendy Sent: September 19, 2019 10:41 PM To: felvtalk@felineleukemia.org Subject: [Felvtalk] Bone Marrow Testing for FELV positive Cat? Hello, Thank you all for your replies earlier today. Our cats' red count is coming back after 2 blood transfusions, and we started doxy today. He is eating, drinking, purring, has much better energy, is back to talking, etc. We are awaiting results that we should have tomorrow morning on the test of his lymphocytes using blood that was drawn before the blood transfusions. If the test comes back showing that the lymphocytes contain cancer cells, then we have our answer. If the test comes back showing that the lymphocytes do not contain cancer cells, then it has been suggested that we do bone marrow testing asap tomorrow afternoon. My understanding is that the bone marrow test would likely either show that he has myelodysplasia or cancer in his bone marrow. My question is: Would the suggested treatment of Doxy + Pred + Winstrol change if we find out that our cat has myelodysplasia vs if he has cancer in his bone marrow? If the treatment is the same, then I question putting our cat at the risk of anesthesia, lowering his red count, infection, etc. The plan is to start our cat on Doxy + Pred + Winstrol tomorrow afternoon, and we are being told that if we want to test his bone marrow we need to do it tomorrow morning before we start giving him steroids. In addition, his chest x-ray today was clean, and his abdominal ultrasound showed a slightly enlarge spleen and either a few slightly enlarged lymph nodes or possibly a few small satellite spleens, all of which seems can be expected with the anemia and / or infection, and therefore was not cause for concern. Following are the background facts, which I also posted this morning: Our FELV positive neutered male cat approximately 1 and ½ years old has gotten very sick suddenly. He is a house cat, and he was neutered in May of 2019. A few days ago, he became lethargic and lost interest in eating. We had his blood drawn yesterday and he had iv fluids yesterday, and today we were told he needed a blood transfusion (or two) and more iv fluids, and then a bone marrow test tomorrow. We were told that the first blood transfusion today was not very effective because he got so many iv fluids at the same time, so now they are going to give him another transfusion. As background, we rescued him as a stray from Barbados in October 2018 when he was about 6 months old, and he has been healthy, active, happy and gaining weight, despite being FELV positive. Since October 2018, we cured him of giardia and bartonella henselae. On 12/31/2018, he tested positive for the ELISA and IFA, although his blood work was in normal ranges at that time. In 03/2019, we started giving him 1 t-cyte shot once per month, and we started giving him 1ml of interferon per days for 7 days on and then 7 days off, repeated. We have continued the interferon and t-cyte in this manner ever since 03/2019. Just yesterday, here are the results of his blood work: Tests ResultsRef. Range Total Protein 6.1 5.2- 8.8 g/dL Albumin 3.5 2.5- 3.9 g/dl Globulin 2.6 2.3- 5.3 g/dL A/G Ratio 1.30.35- 1.5 AST (SGOT) 106 (HIGH) 10-100 IU/L ALT (SGPT) 3910- 100 IU/L Alk Phosphatase406- 102 IU/L GGT 11- 10 IU/L Total Bilirubin 0.1 0.1- 0.4 mg/dL BUN 1514- 36 mg/dl Creatinine 0.9 0.6- 2.4 mg/dl BUN/Creatinine Ratio 17
[Felvtalk] Bone Marrow Testing for FELV positive Cat?
Hello, Thank you all for your replies earlier today. Our cats' red count is coming back after 2 blood transfusions, and we started doxy today. He is eating, drinking, purring, has much better energy, is back to talking, etc. We are awaiting results that we should have tomorrow morning on the test of his lymphocytes using blood that was drawn before the blood transfusions. If the test comes back showing that the lymphocytes contain cancer cells, then we have our answer. If the test comes back showing that the lymphocytes do not contain cancer cells, then it has been suggested that we do bone marrow testing asap tomorrow afternoon. My understanding is that the bone marrow test would likely either show that he has myelodysplasia or cancer in his bone marrow. My question is: Would the suggested treatment of Doxy + Pred + Winstrol change if we find out that our cat has myelodysplasia vs if he has cancer in his bone marrow? If the treatment is the same, then I question putting our cat at the risk of anesthesia, lowering his red count, infection, etc. The plan is to start our cat on Doxy + Pred + Winstrol tomorrow afternoon, and we are being told that if we want to test his bone marrow we need to do it tomorrow morning before we start giving him steroids. In addition, his chest x-ray today was clean, and his abdominal ultrasound showed a slightly enlarge spleen and either a few slightly enlarged lymph nodes or possibly a few small satellite spleens, all of which seems can be expected with the anemia and / or infection, and therefore was not cause for concern. Following are the background facts, which I also posted this morning: Our FELV positive neutered male cat approximately 1 and ½ years old has gotten very sick suddenly. He is a house cat, and he was neutered in May of 2019. A few days ago, he became lethargic and lost interest in eating. We had his blood drawn yesterday and he had iv fluids yesterday, and today we were told he needed a blood transfusion (or two) and more iv fluids, and then a bone marrow test tomorrow. We were told that the first blood transfusion today was not very effective because he got so many iv fluids at the same time, so now they are going to give him another transfusion. As background, we rescued him as a stray from Barbados in October 2018 when he was about 6 months old, and he has been healthy, active, happy and gaining weight, despite being FELV positive. Since October 2018, we cured him of giardia and bartonella henselae. On 12/31/2018, he tested positive for the ELISA and IFA, although his blood work was in normal ranges at that time. In 03/2019, we started giving him 1 t-cyte shot once per month, and we started giving him 1ml of interferon per days for 7 days on and then 7 days off, repeated. We have continued the interferon and t-cyte in this manner ever since 03/2019. Just yesterday, here are the results of his blood work: Tests ResultsRef. Range Total Protein 6.1 5.2- 8.8 g/dL Albumin 3.5 2.5- 3.9 g/dl Globulin 2.6 2.3- 5.3 g/dL A/G Ratio 1.30.35- 1.5 AST (SGOT) 106 (HIGH) 10-100 IU/L ALT (SGPT) 3910- 100 IU/L Alk Phosphatase406- 102 IU/L GGT 11- 10 IU/L Total Bilirubin 0.1 0.1- 0.4 mg/dL BUN 1514- 36 mg/dl Creatinine 0.9 0.6- 2.4 mg/dl BUN/Creatinine Ratio 17 4-33 Phosphorus4.4 2.4- 8.2 mg/dl Glucose178 (HIGH) 64 - 170 mg/dL Calcium 9.38.2- 10 .8 mg/dL Magnesium2.0 1.5- 2.5 mEq/L Sodium 153 145-158 mEq/L Potassium 4.6 3.4- 5.6 mEq/L NAIK Ratio 3332-41 Chloride121 104-128 mEq/L Cholesterol9475- 220 mg/dl Triglyceride108 25-160 mg/dl Amylase 611 100-1200 IU/L PrecisionPSL(tm) 10 8- 26 U/L Acute pancreatitis is unlikely. Chronic pancreatitis is not excluded. CPK 711 (HIGH) 56-529 IU/L WBC 20.5 (HIGH)3.5- 16.0 10'/µL Corrected for NRBCs ABC 2.5 (LOW)5.92-9.93 10°/µ L HGB
