Re: [Felvtalk] Update on Tigger's Condition

[Rachel Dagner]

Wow! That is an amazing story! So glad you are here to tell it. I am hoping by 
boosting Tucker's immune system I can help his body kick into fighting mode. 
What is really weird is that his blood work is all completely normal. My vet 
told me sometimes it is even with cancer. I guess the only way I will be able 
to tell if he is improving is do another X-ray in several months and see if it 
looks the same. 

Sent from my iPhone

> On Apr 29, 2016, at 5:53 PM,   
> wrote:
> 
> when i had lyphoma, the last chemo knocked my red cells down and the dr 
> stopped it.  i am wondering if this would help humans fighting lyphoma and 
> chemo?  what is it's shelf life?  might not hurt to have some on hand just in 
> case.  YES, i would be willing to try it siince the dr. told me none of the 
> chemos did any good nd i was back to 3 months.  1 year later i went into 
> spontaneous remission and have been there now for 10 years.  maybe if we had 
> ghone with winstrol to begin with.
> 
> 
>  Amani Oakley  wrote: 
>> Hi Everyone
>> 
>> With Ardy's permission, I want to share with everyone, the very promising 
>> results we have gotten with the use of Winstrol.
>> 
>> When Ardy first contacted me, she provided me with Tigger's lab results. As 
>> Ardy has mentioned, the results were pretty grim. The key findings for me 
>> were:
>> 
>> March 12/16 Red Cells:  1.07(RR: 5-10)
>>Haematocrit 6.3 (RR: 30.0 - 45.0%)
>>Haemoglobin 4.6 (RR: 9.0 - 15.1)
>>Reticulocyte5.2%
>>WBC 3.3 (RR: 5.5 - 19.5)
>>%Neutrophils16.4%
>>%Lymphocytes64.0%
>>%Monocytes
>>NRBCNone recorded
>> 
>> Even though there are no reference ranges listed for the percentage 
>> distribution of neutrophils and lymphocytes, I know this distribution 
>> pattern is abnormal. There should be more neutrophils and lymphocytes in 
>> cats, with the ratio being something like 1.8/1, so maybe 45% neutrophils 
>> and 25% to 35% lymphocytes would be the kind of range one would like to see. 
>> The very high lymphocyte count here (higher than the neutrophils) suggests 
>> these are leukemic cells - ie abnormal lymphocytes produced as a result of 
>> the viral infection.
>> 
>> Ardy frantically tried all kinds of places to get the Winstrol and she was 
>> finally able to get some and start Tigger on it, on March 15 - so three days 
>> after this blood work was drawn.
>> 
>> The next set of blood results showed an slight increase in red cells, a 
>> significant increase in the haematocrit, haemoglobin, reticulocytes, and a 
>> reversion of the neutrophil/lymphocyte distribution to what one would prefer 
>> to see.
>> 
>> March 25/16 Red Cells   1.70(RR: 5-10)
>>Haematocrit 14.1(RR: 30.0 - 45%)
>>Haemoglobin 4.6 (RR: 9.0 - 15.1)
>>Reticulocyte(Not done)
>>WBC 3.1 (RR: 5.5 - 19.5)
>>%Neutrophils43%
>>%Lymphocytes20%
>>%Monocytes  26%
>>%Blasts 9%
>>NRBC9/100 WBC   (Normal is 0)
>> 
>> 
>> So we started to see a slight increase in the red cell count (which although 
>> it still is well out of reference range, is a 70% in increase from the 
>> previous awful result. The haematocrit more than doubled. The haemoglobin 
>> stayed about the same. The reticulocyte level wasn't done but we started to 
>> see nucleated red blood cells (NRBC) appearing, which are immature red cells 
>> which still have their nuclei - mature red cells do not have nuclei. This 
>> indicates they are being pushed out early by the bone marrow in response to 
>> the low red cell count. The neutrophil/lymphocyte ratio has normalized, but 
>> the monocytes are quite high (usually are low like 2% or so) and are 
>> indicative of an inflammatory process going on. The total white cell count 
>> was still lower than the reference range, suggesting a depression of this 
>> cell line as well.
>> 
>> Not surprisingly, the pathologist who reviewed this set of blood results 
>> said (in part) the following: "This anemia appears NON-REGENERATIVE, and 
>> although I can't confirm the exact cause based on this CBC alone, given this 
>> appearance, and especially the macrocytosis [elevated monocytes] and 
>> metarubricytosis [presence of lots of nucleated red blood cells] and in the 
>> face of minimal polychromasia, FeLV is my top differential. . . . The blasts 
>> noted do appear consistent with lymphoblasts. . . While they could be 
>> neoplastic, their overall concentration is small, and I could not confirm 
>> neoplasia as seen here."
>> 
>> In the meantime, Ardy was reporting that Tigger was not needing as much pain 
>> medication 

Re: [Felvtalk] Update on Tigger's Condition

[dlgegg]

when i had lyphoma, the last chemo knocked my red cells down and the dr stopped 
it.  i am wondering if this would help humans fighting lyphoma and chemo?  what 
is it's shelf life?  might not hurt to have some on hand just in case.  YES, i 
would be willing to try it siince the dr. told me none of the chemos did any 
good nd i was back to 3 months.  1 year later i went into spontaneous remission 
and have been there now for 10 years.  maybe if we had ghone with winstrol to 
begin with.


 Amani Oakley  wrote: 
> Hi Everyone
> 
> With Ardy's permission, I want to share with everyone, the very promising 
> results we have gotten with the use of Winstrol.
> 
> When Ardy first contacted me, she provided me with Tigger's lab results. As 
> Ardy has mentioned, the results were pretty grim. The key findings for me 
> were:
> 
> March 12/16 Red Cells:  1.07(RR: 5-10)
> Haematocrit 6.3 (RR: 30.0 - 45.0%)
> Haemoglobin 4.6 (RR: 9.0 - 15.1)
> Reticulocyte5.2%
> WBC 3.3 (RR: 5.5 - 19.5)
> %Neutrophils16.4%
> %Lymphocytes64.0%
> %Monocytes
> NRBCNone recorded
> 
> Even though there are no reference ranges listed for the percentage 
> distribution of neutrophils and lymphocytes, I know this distribution pattern 
> is abnormal. There should be more neutrophils and lymphocytes in cats, with 
> the ratio being something like 1.8/1, so maybe 45% neutrophils and 25% to 35% 
> lymphocytes would be the kind of range one would like to see. The very high 
> lymphocyte count here (higher than the neutrophils) suggests these are 
> leukemic cells - ie abnormal lymphocytes produced as a result of the viral 
> infection.
> 
> Ardy frantically tried all kinds of places to get the Winstrol and she was 
> finally able to get some and start Tigger on it, on March 15 - so three days 
> after this blood work was drawn.
> 
> The next set of blood results showed an slight increase in red cells, a 
> significant increase in the haematocrit, haemoglobin, reticulocytes, and a 
> reversion of the neutrophil/lymphocyte distribution to what one would prefer 
> to see.
> 
> March 25/16 Red Cells   1.70(RR: 5-10)
> Haematocrit 14.1(RR: 30.0 - 45%)
> Haemoglobin 4.6 (RR: 9.0 - 15.1)
> Reticulocyte(Not done)
> WBC 3.1 (RR: 5.5 - 19.5)
> %Neutrophils43%
> %Lymphocytes20%
> %Monocytes  26%
> %Blasts 9%
> NRBC9/100 WBC   (Normal is 0)
> 
> 
> So we started to see a slight increase in the red cell count (which although 
> it still is well out of reference range, is a 70% in increase from the 
> previous awful result. The haematocrit more than doubled. The haemoglobin 
> stayed about the same. The reticulocyte level wasn't done but we started to 
> see nucleated red blood cells (NRBC) appearing, which are immature red cells 
> which still have their nuclei - mature red cells do not have nuclei. This 
> indicates they are being pushed out early by the bone marrow in response to 
> the low red cell count. The neutrophil/lymphocyte ratio has normalized, but 
> the monocytes are quite high (usually are low like 2% or so) and are 
> indicative of an inflammatory process going on. The total white cell count 
> was still lower than the reference range, suggesting a depression of this 
> cell line as well.
> 
> Not surprisingly, the pathologist who reviewed this set of blood results said 
> (in part) the following: "This anemia appears NON-REGENERATIVE, and although 
> I can't confirm the exact cause based on this CBC alone, given this 
> appearance, and especially the macrocytosis [elevated monocytes] and 
> metarubricytosis [presence of lots of nucleated red blood cells] and in the 
> face of minimal polychromasia, FeLV is my top differential. . . . The blasts 
> noted do appear consistent with lymphoblasts. . . While they could be 
> neoplastic, their overall concentration is small, and I could not confirm 
> neoplasia as seen here."
> 
> In the meantime, Ardy was reporting that Tigger was not needing as much pain 
> medication (or any at all), and began to eat on his own.
> 
> 
> The last set of blood results showed:
> 
> April 26/16 Red Cells   1.67(RR: 5-10)
> Haematocrit 12.2(RR 30.0 - 45%)
> Haemoglobin 4.6 (RR: 9.0 - 15.1)
> Reticulocyte10.31%  (Not usually seen)
> WBC 4.9 (RR: 5.5 - 19.5)
> %Neutrophils45%
> %Lymphocytes40%
> %Monocytes  3%
> %Blasts 12%
> NRBC95/100 WBC  (Normal is 0)
> 
> 

[Felvtalk] Update on Tigger's Condition

[Amani Oakley]

Hi Everyone

With Ardy's permission, I want to share with everyone, the very promising 
results we have gotten with the use of Winstrol.

When Ardy first contacted me, she provided me with Tigger's lab results. As 
Ardy has mentioned, the results were pretty grim. The key findings for me were:

March 12/16 Red Cells:  1.07(RR: 5-10)
Haematocrit 6.3 (RR: 30.0 - 45.0%)
Haemoglobin 4.6 (RR: 9.0 - 15.1)
Reticulocyte5.2%
WBC 3.3 (RR: 5.5 - 19.5)
%Neutrophils16.4%
%Lymphocytes64.0%
%Monocytes
NRBCNone recorded

Even though there are no reference ranges listed for the percentage 
distribution of neutrophils and lymphocytes, I know this distribution pattern 
is abnormal. There should be more neutrophils and lymphocytes in cats, with the 
ratio being something like 1.8/1, so maybe 45% neutrophils and 25% to 35% 
lymphocytes would be the kind of range one would like to see. The very high 
lymphocyte count here (higher than the neutrophils) suggests these are leukemic 
cells - ie abnormal lymphocytes produced as a result of the viral infection.

Ardy frantically tried all kinds of places to get the Winstrol and she was 
finally able to get some and start Tigger on it, on March 15 - so three days 
after this blood work was drawn.

The next set of blood results showed an slight increase in red cells, a 
significant increase in the haematocrit, haemoglobin, reticulocytes, and a 
reversion of the neutrophil/lymphocyte distribution to what one would prefer to 
see.

March 25/16 Red Cells   1.70(RR: 5-10)
Haematocrit 14.1(RR: 30.0 - 45%)
Haemoglobin 4.6 (RR: 9.0 - 15.1)
Reticulocyte(Not done)
WBC 3.1 (RR: 5.5 - 19.5)
%Neutrophils43%
%Lymphocytes20%
%Monocytes  26%
%Blasts 9%
NRBC9/100 WBC   (Normal is 0)


So we started to see a slight increase in the red cell count (which although it 
still is well out of reference range, is a 70% in increase from the previous 
awful result. The haematocrit more than doubled. The haemoglobin stayed about 
the same. The reticulocyte level wasn't done but we started to see nucleated 
red blood cells (NRBC) appearing, which are immature red cells which still have 
their nuclei - mature red cells do not have nuclei. This indicates they are 
being pushed out early by the bone marrow in response to the low red cell 
count. The neutrophil/lymphocyte ratio has normalized, but the monocytes are 
quite high (usually are low like 2% or so) and are indicative of an 
inflammatory process going on. The total white cell count was still lower than 
the reference range, suggesting a depression of this cell line as well.

Not surprisingly, the pathologist who reviewed this set of blood results said 
(in part) the following: "This anemia appears NON-REGENERATIVE, and although I 
can't confirm the exact cause based on this CBC alone, given this appearance, 
and especially the macrocytosis [elevated monocytes] and metarubricytosis 
[presence of lots of nucleated red blood cells] and in the face of minimal 
polychromasia, FeLV is my top differential. . . . The blasts noted do appear 
consistent with lymphoblasts. . . While they could be neoplastic, their overall 
concentration is small, and I could not confirm neoplasia as seen here."

In the meantime, Ardy was reporting that Tigger was not needing as much pain 
medication (or any at all), and began to eat on his own.


The last set of blood results showed:

April 26/16 Red Cells   1.67(RR: 5-10)
Haematocrit 12.2(RR 30.0 - 45%)
Haemoglobin 4.6 (RR: 9.0 - 15.1)
Reticulocyte10.31%  (Not usually seen)
WBC 4.9 (RR: 5.5 - 19.5)
%Neutrophils45%
%Lymphocytes40%
%Monocytes  3%
%Blasts 12%
NRBC95/100 WBC  (Normal is 0)

So, looking at these results, I was initially concerned because of the slight 
slippage of the red cell count but then I realized that if you combine the red 
cells with the massive increase of nucleated red blood cells (95 per 100 WBC's) 
and also add the reticulocytes (an even more immature form of red cells), then 
we would actually be seeing a much much increased red cell count. (See the 
comments from the Pathologist, which follow, to see that he also has picked up 
on this.) I was also concerned about the drop in haematocrit but then I 
recognized that the red cells are becoming more normal in size (they were quite 
macrocytic in the last blood sample), so it would show a drop because it is 
machine calculation. I