Re: [Felvtalk] Research into FeLV: was Staph Protein A

2009-08-12 Thread hebert ferrarezzi

Hi  MaryChristine and Gloria,
FIV is in fact a closer relative to HIV than is FeLV.  The three belong to the 
same retrovirus family and subfamily, but FeLV belongs to the Gammaretrovirus 
group, whereas FIV and HIV belong to the Lentivirus group.  The severe outcomes 
of the disease, however, make feline leukemia more analogous to AIDS in some 
aspects.
The discovery of HIV as the causal agent of human immunodeficiency was due to 
the previous knowledge that FeLV (not FIV) virus causes a similar syndrome in 
cats. 
Moreover, FeLV is a model for the study of cancer.  Indeed, most of the papers 
I have cited here about the use of Protein A came from the research group of 
the late Robert A. Good, a renamed immunologist and oncologist  
http://www.robertagoodarchives.com/biography.html 
 
Hebert 

 
 From: twelvehousec...@gmail.com
 Date: Mon, 10 Aug 2009 11:07:37 -0400
 To: felvtalk@felineleukemia.org
 Subject: [Felvtalk] Research into FeLV: was Staph Protein A
 
 wow, hebert, thank you for these great posts! (and your english is better
 than many who claim to be native speakers.)
 
 i have always been under the impression, tho, that FIV, not FeLV, was
 considered by researchers to be more analogous to HIV/AIDS (an early
 hypothesis which i believe has been adequately disproven), even tho it
 appears to those of us who aren't scientists but have done the best reading
 they can that FeLV is much closer in manner of transmission, manifestation,
 and course.
 
 gary, have pedersen or levy done any work with this? they're the two folks,
 off-hand, that i can think of who have consistently continued actually
 researching FeLV--susan little, as well, seems to have been fairly on top of
 what research is going on. might they know about any researchers
 currently working on this?
 
 i remember when i first got involved with FeLV, from living at a sanctuary,
 and i was asking why no one was doing safe, minimally invasive research on
 the three main populations of FeLVs in the countries, at that time Best
 Friends, us, and Angel Wings (in terms of population size)--i was told then
 that answering the questions that folks on this list and others were already
 asking would probably require catching the interest of a drug company, as
 private or academic researchers wouldn't likely have the funding. (back
 to my usual comment about how difficult it is to do research on a population
 that is regularly treated by immediate euthanasia.)
 
 i'm not sure how many folks here really realize that a great deal of
 research on genetic conditions in cats could not have come about without the
 involvement--and fundraising--on the part of breeders, determined to
 eradicate killers in their own breeds (HCM in maine coons and bengals
 immediately comes to mind.) FeLV owners aren't as identifiable an entity as
 cattery owners, and while their emotional investment is just as great, i'm
 not sure how to mobilize us to perhaps do the same for this illness.
 
 
 -- 
 Spay  Neuter Your Neighbors!
 Maybe That'll Make The Difference
 
 MaryChristine
 Special-Needs Coordinator, Purebred Cat Breed Rescue (www.purebredcats.org)
 Member, SCAT (Special-Cat Action Team)
 ___
 Felvtalk mailing list
 Felvtalk@felineleukemia.org
 http://felineleukemia.org/mailman/listinfo/felvtalk_felineleukemia.org

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Re: [Felvtalk] Research into FeLV: was Staph Protein A

2009-08-12 Thread Gloria B. Lane
Thanks, Hebert, that's interesting, and glad to have the info  
correctly.  However, I also wonder why FIV cats have so little problem  
- seems like HIV causes problems (Aids) quite frequently, but in my  
experience, FIV cats rarely have FIV related problems.  Any thoughts  
or info on that?


Thanks,

Gloria




On Aug 12, 2009, at 8:14 AM, hebert ferrarezzi wrote:



Hi  MaryChristine and Gloria,
FIV is in fact a closer relative to HIV than is FeLV.  The three  
belong to the same retrovirus family and subfamily, but FeLV belongs  
to the Gammaretrovirus group, whereas FIV and HIV belong to the  
Lentivirus group.  The severe outcomes of the disease, however, make  
feline leukemia more analogous to AIDS in some aspects.
The discovery of HIV as the causal agent of human immunodeficiency  
was due to the previous knowledge that FeLV (not FIV) virus causes a  
similar syndrome in cats.
Moreover, FeLV is a model for the study of cancer.  Indeed, most of  
the papers I have cited here about the use of Protein A came from  
the research group of the late Robert A. Good, a renamed  
immunologist and oncologist  http://www.robertagoodarchives.com/biography.html


Hebert



From: twelvehousec...@gmail.com
Date: Mon, 10 Aug 2009 11:07:37 -0400
To: felvtalk@felineleukemia.org
Subject: [Felvtalk] Research into FeLV: was Staph Protein A

wow, hebert, thank you for these great posts! (and your english is  
better

than many who claim to be native speakers.)

i have always been under the impression, tho, that FIV, not FeLV, was
considered by researchers to be more analogous to HIV/AIDS (an early
hypothesis which i believe has been adequately disproven), even tho  
it
appears to those of us who aren't scientists but have done the best  
reading
they can that FeLV is much closer in manner of transmission,  
manifestation,

and course.

gary, have pedersen or levy done any work with this? they're the  
two folks,
off-hand, that i can think of who have consistently continued  
actually
researching FeLV--susan little, as well, seems to have been fairly  
on top of

what research is going on. might they know about any researchers
currently working on this?

i remember when i first got involved with FeLV, from living at a  
sanctuary,
and i was asking why no one was doing safe, minimally invasive  
research on
the three main populations of FeLVs in the countries, at that time  
Best
Friends, us, and Angel Wings (in terms of population size)--i was  
told then
that answering the questions that folks on this list and others  
were already
asking would probably require catching the interest of a drug  
company, as
private or academic researchers wouldn't likely have the  
funding. (back
to my usual comment about how difficult it is to do research on a  
population

that is regularly treated by immediate euthanasia.)

i'm not sure how many folks here really realize that a great deal of
research on genetic conditions in cats could not have come about  
without the

involvement--and fundraising--on the part of breeders, determined to
eradicate killers in their own breeds (HCM in maine coons and bengals
immediately comes to mind.) FeLV owners aren't as identifiable an  
entity as
cattery owners, and while their emotional investment is just as  
great, i'm
not sure how to mobilize us to perhaps do the same for this  
illness.



--
Spay  Neuter Your Neighbors!
Maybe That'll Make The Difference

MaryChristine
Special-Needs Coordinator, Purebred Cat Breed Rescue (www.purebredcats.org 
)

Member, SCAT (Special-Cat Action Team)
___
Felvtalk mailing list
Felvtalk@felineleukemia.org
http://felineleukemia.org/mailman/listinfo/ 
felvtalk_felineleukemia.org


_
Deixe suas conversas mais divertidas. Baixe agora mesmo novos  
emoticons. É grátis!

http://specials.br.msn.com/ilovemessenger/pacotes.aspx
___
Felvtalk mailing list
Felvtalk@felineleukemia.org
http://felineleukemia.org/mailman/listinfo/felvtalk_felineleukemia.org



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Re: [Felvtalk] Research into FeLV: was Staph Protein A

2009-08-12 Thread MaryChristine
hebert, i understand the fact that in terms of groups, FIV is closer to HIV
than FeLV is, but I think it's very confusing to most people to say that
they are comparable when you look at how they are transmitted. As you and i
and gloria all say, FeLV acts more like HIV/AIDS than FIV does, and it seems
that FIV's name itself has caused far more deaths than the virus itself. i
keep thinking that, had it not been identified as a separate entity in the
late 80s, (86? 87? i should be able to remember) the heyday of the
HIV/AIDS panic. Should FIV be renamed, so that the immediate association is
no longer made, and so the misnomer, Feline AIDS, would be less often
used?

Or, perhaps, could we in the field, begin to add a disclaimer like, FIV,
while it is a lentivirus like HIV/AIDS, is less similar than is FeLV in its
presentation in cats or something less pompous but more accessible

it seems that, this summer, especially, there is LESS understanding all over
this country, of what FIV actually is and does and how its transmitted! FIVs
are, to be technical, coming out of our ears.

sigh.

we still need to get researchers -- and funding sources -- interested in
looking at BOTH of these viruses.

MC

-- 
Spay  Neuter Your Neighbors!
Maybe That'll Make The Difference

MaryChristine
Special-Needs Coordinator, Purebred Cat Breed Rescue (www.purebredcats.org)
Member, SCAT (Special-Cat Action Team)
___
Felvtalk mailing list
Felvtalk@felineleukemia.org
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Re: [Felvtalk] Research into FeLV: was Staph Protein A

2009-08-10 Thread Gloria B. Lane
I've read this too, MC, that FELV is considered a closer analogy to  
HIV...


Gloria


On Aug 10, 2009, at 10:07 AM, MaryChristine wrote:

wow, hebert, thank you for these great posts! (and your english is  
better

than many who claim to be native speakers.)

i have always been under the impression, tho, that FIV, not FeLV, was
considered by researchers to be more analogous to  HIV/AIDS (an early
hypothesis which i believe has been adequately disproven), even tho it
appears to those of us who aren't scientists but have done the best  
reading
they can that FeLV is much closer in manner of transmission,  
manifestation,

and course.

gary, have pedersen or levy done any work with this? they're the two  
folks,

off-hand, that i can think of who have consistently continued actually
researching FeLV--susan little, as well, seems to have been fairly  
on top of

what research is going on. might they know about any researchers
currently working on this?

i remember when i first got involved with FeLV, from living at a  
sanctuary,
and i was asking why no one was doing safe, minimally invasive  
research on
the three main populations of FeLVs in the countries, at that time  
Best
Friends, us, and Angel Wings (in terms of population size)--i was  
told then
that answering the questions that folks on this list and others were  
already
asking would probably require catching the interest of a drug  
company, as
private or academic researchers wouldn't likely have the  
funding. (back
to my usual comment about how difficult it is to do research on a  
population

that is regularly treated by immediate euthanasia.)

i'm not sure how many folks here really realize that a great deal of
research on genetic conditions in cats could not have come about  
without the

involvement--and fundraising--on the part of breeders, determined to
eradicate killers in their own breeds (HCM in maine coons and bengals
immediately comes to mind.) FeLV owners aren't as identifiable an  
entity as
cattery owners, and while their emotional investment is just as  
great, i'm
not sure how to mobilize us to perhaps do the same for this  
illness.



--
Spay  Neuter Your Neighbors!
Maybe That'll Make The Difference

MaryChristine
Special-Needs Coordinator, Purebred Cat Breed Rescue (www.purebredcats.org 
)

Member, SCAT (Special-Cat Action Team)
___
Felvtalk mailing list
Felvtalk@felineleukemia.org
http://felineleukemia.org/mailman/listinfo/felvtalk_felineleukemia.org



___
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Felvtalk@felineleukemia.org
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Re: [Felvtalk] Research into FeLV: was Staph Protein A

2009-08-10 Thread gary
I haven't heard that anyone is presently doing any research on felines with
Staph Protein A.  What would really be frustrating would be to find someone
to do it and have great success and then not be able to get Staph Protein A
because it is not authorized as a drug or treatment for anything.  Maybe we
could get the USDA to give a provisional license like LTCI has if we can get
someone to do a research project.  As you know, LTCI did not have a LOT of
data when they got the license for that.

Gary

-Original Message-
From: felvtalk-boun...@felineleukemia.org
[mailto:felvtalk-boun...@felineleukemia.org] On Behalf Of MaryChristine
Sent: Monday, August 10, 2009 10:08 AM
To: felvtalk@felineleukemia.org
Subject: [Felvtalk] Research into FeLV: was Staph Protein A

wow, hebert, thank you for these great posts! (and your english is better
than many who claim to be native speakers.)

i have always been under the impression, tho, that FIV, not FeLV, was
considered by researchers to be more analogous to  HIV/AIDS (an early
hypothesis which i believe has been adequately disproven), even tho it
appears to those of us who aren't scientists but have done the best reading
they can that FeLV is much closer in manner of transmission, manifestation,
and course.

gary, have pedersen or levy done any work with this? they're the two folks,
off-hand, that i can think of who have consistently continued actually
researching FeLV--susan little, as well, seems to have been fairly on top of
what research is going on. might they know about any researchers
currently working on this?

i remember when i first got involved with FeLV, from living at a sanctuary,
and i was asking why no one was doing safe, minimally invasive research on
the three main populations of FeLVs in the countries, at that time Best
Friends, us, and Angel Wings (in terms of population size)--i was told then
that answering the questions that folks on this list and others were already
asking would probably require catching the interest of a drug company, as
private or academic researchers wouldn't likely have the funding. (back
to my usual comment about how difficult it is to do research on a population
that is regularly treated by immediate euthanasia.)

i'm not sure how many folks here really realize that a great deal of
research on genetic conditions in cats could not have come about without the
involvement--and fundraising--on the part of breeders, determined to
eradicate killers in their own breeds (HCM in maine coons and bengals
immediately comes to mind.) FeLV owners aren't as identifiable an entity as
cattery owners, and while their emotional investment is just as great, i'm
not sure how to mobilize us to perhaps do the same for this illness.




___
Felvtalk mailing list
Felvtalk@felineleukemia.org
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Re: [Felvtalk] Research into FeLV: was Staph Protein A

2009-08-10 Thread MaryChristine
On Mon, Aug 10, 2009 at 1:22 PM, gary gcru...@centurytel.net wrote:

 I haven't heard that anyone is presently doing any research on felines with
 Staph Protein A.  What would really be frustrating would be to find someone
 to do it and have great success and then not be able to get Staph Protein A
 because it is not authorized as a drug or treatment for anything.  Maybe we
 could get the USDA to give a provisional license like LTCI has if we can
 get
 someone to do a research project.  As you know, LTCI did not have a LOT of
 data when they got the license for that.

 Gary

 -Original Message-
 From: felvtalk-boun...@felineleukemia.org
 [mailto:felvtalk-boun...@felineleukemia.org] On Behalf Of MaryChristine
 Sent: Monday, August 10, 2009 10:08 AM
 To: felvtalk@felineleukemia.org
 Subject: [Felvtalk] Research into FeLV: was Staph Protein A

 wow, hebert, thank you for these great posts! (and your english is better
 than many who claim to be native speakers.)

 i have always been under the impression, tho, that FIV, not FeLV, was
 considered by researchers to be more analogous to  HIV/AIDS (an early
 hypothesis which i believe has been adequately disproven), even tho it
 appears to those of us who aren't scientists but have done the best reading
 they can that FeLV is much closer in manner of transmission, manifestation,
 and course.

 gary, have pedersen or levy done any work with this? they're the two folks,
 off-hand, that i can think of who have consistently continued actually
 researching FeLV--susan little, as well, seems to have been fairly on top
 of
 what research is going on. might they know about any researchers
 currently working on this?

 i remember when i first got involved with FeLV, from living at a sanctuary,
 and i was asking why no one was doing safe, minimally invasive research on
 the three main populations of FeLVs in the countries, at that time Best
 Friends, us, and Angel Wings (in terms of population size)--i was told then
 that answering the questions that folks on this list and others were
 already
 asking would probably require catching the interest of a drug company, as
 private or academic researchers wouldn't likely have the funding. (back
 to my usual comment about how difficult it is to do research on a
 population
 that is regularly treated by immediate euthanasia.)

 i'm not sure how many folks here really realize that a great deal of
 research on genetic conditions in cats could not have come about without
 the
 involvement--and fundraising--on the part of breeders, determined to
 eradicate killers in their own breeds (HCM in maine coons and bengals
 immediately comes to mind.) FeLV owners aren't as identifiable an entity as
 cattery owners, and while their emotional investment is just as great, i'm
 not sure how to mobilize us to perhaps do the same for this illness.




 ___
 Felvtalk mailing list
 Felvtalk@felineleukemia.org
 http://felineleukemia.org/mailman/listinfo/felvtalk_felineleukemia.org




-- 
Spay  Neuter Your Neighbors!
Maybe That'll Make The Difference

MaryChristine
Special-Needs Coordinator, Purebred Cat Breed Rescue (www.purebredcats.org)
Member, SCAT (Special-Cat Action Team)
___
Felvtalk mailing list
Felvtalk@felineleukemia.org
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