Dear Michel and FIS colleagues,

Thanks for the very accurate Intro. I am reluctant to discuss about 
biological information right now, as there are other aspects you have 
dealt with that deserve further discussion. The story itself is funny: 
the way new fields of multidisciplinary origins have to swim against the 
strong forces of institutional "viscosity" --probably the stunning 
success of bioinformatics also contributed to the revival of cheminfo in 
France (and elsewhere). That's fodder for my "scientomics" perspective, 
the interpenetration or recombination of fields as the usual origin of 
new disciplines ...  by the way, the proper term in English should be 
Chemoinformatics or Cheminformatics? I have seen both in the literature.

The relationship  between scientific practice, Data Mining (DM) and 
Knowledge Discovery in Databases (KDD) is another crucial informational 
aspect you enter. Where is information? For my taste, every major 
discipline has provided its own answer, but implicitly, and that 
contributes to the impossibility to give a consistent answer to your 
questions about that. The discussion could be too long, beyond my typing 
possibilities today... I think however that bioinformation can give some 
serious points precisely by means of DM and KDD related tools --my bet 
is that the technology of "microarrays" in systems biology and 
bionformatics will be able to tell us what is "meaning" at the cellular 
scale. But an in depth discussion of the chemical background would be 
needed.

Continuing with Gavin's --there is a grain of truth in some of his 
rejections-- precisely I see Info Science as the attempt to achieve 
multidisciplinary consistency around the whole familiy of info concepts, 
even probably assuming that info itself cannot be defined, although you 
can measure it, process it,  etc.  That's not pejorative, can anyone 
define "time", or "symmetry"? Biologically speaking there is not much to 
discuss: metabolism is what our cells "eat", signaling is about the 
"information they "read" from the environment. It is written in 
chemicals, like our newspapers (in ink), but cells do not eat it, the 
same way we do not eat newspapers (unless in onion paper!). Veteran 
Fisers will remember a funny exchange with Igor many years ago, Father 
Brown related...

best wishes

--Pedro

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Pedro C. Marijuán
Grupo de Bioinformación / Bioinformation Group
Instituto Aragonés de Ciencias de la Salud
Avda. Gómez Laguna, 25, Pl. 11ª
50009 Zaragoza, Spain
Telf: 34 976 71 3526 (& 6818) Fax: 34 976 71 5554
pcmarijuan.i...@aragon.es
http://sites.google.com/site/pedrocmarijuan/
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