Re: [Freesurfer] Cortical thickness using qdec (between scanners)

2016-10-12 Thread Douglas N Greve
That is surface-based smoothing. the voxel size differences create differences in volume-based smoothing (a partial volume effect). I don't know of a good way to simulate volume-based PVC. This cannot be done in qdec On 10/06/2016 06:36 PM, Martin Juneja wrote: > Dear Dr. Greve, > > Thanks a

Re: [Freesurfer] Cortical thickness using qdec (between scanners)

2016-10-06 Thread Martin Juneja
Dear Dr. Greve, Thanks a lot for your inputs on this. In the manual- https://surfer.nmr.mgh.harvard.edu/fswiki/FsTutorial/QdecGroupAnalysis_freeview, in qdec it shows there is an option to select 'Smoothing (FWHM)' under the step 'Design'. Could you please share your thoughts if there is any

Re: [Freesurfer] Cortical thickness using qdec (between scanners)

2016-10-05 Thread Douglas N Greve
I think the difference in voxel size (1mm vs 1.3mm) is problematic. You will get more smoothing with the 1.3mm (ie, partial volume effects), and that could easily show up in the thickness measurements On 10/05/2016 12:19 PM, Martin Juneja wrote: > Hi Dr. Greve, > > After I compare the two

Re: [Freesurfer] Cortical thickness using qdec (between scanners)

2016-10-05 Thread Martin Juneja
Hi Dr. Greve, After I compare the two protocols (after using mri_info in FSL on raw dicom file), I get following parameters used in both the protocols. After looking at both the protocols parameters below, could you please share your thoughts on whether parameters are in match enough to go ahead

Re: [Freesurfer] Cortical thickness using qdec (between scanners)

2016-10-03 Thread Douglas N Greve
I would still say no -- the differences could still be due to differences in acquisition parameters On 10/03/2016 02:30 PM, Martin Juneja wrote: > Thanks Dr. Harms and Dr. Greve. > So can I do the cortical thickness comparison if we have healthy > controls data from the same scanner but

Re: [Freesurfer] Cortical thickness using qdec (between scanners)

2016-10-03 Thread Martin Juneja
Thanks Dr. Harms and Dr. Greve. So can I do the cortical thickness comparison if we have healthy controls data from the same scanner but acquired using different protocol e.g. if we get access of age-matched healthy controls data from another lab who used the same scanner? Thanks. On Fri, Sep

Re: [Freesurfer] Cortical thickness using qdec (between scanners)

2016-09-30 Thread Douglas N Greve
You can do the comparison, but the interpretation is difficult. If you see a difference, how do you know it is not due to the scanner? There's not much you can do ... On 09/29/2016 02:54 PM, Martin Juneja wrote: > Hello FS experts, > > I have a data set of 20 subjects (patients) collected at

Re: [Freesurfer] Cortical thickness using qdec (between scanners)

2016-09-29 Thread Harms, Michael
t; Subject: [Freesurfer] Cortical thickness using qdec (between scanners) Hello FS experts, I have a data set of 20 subjects (patients) collected at location-1 with 3T Siemens scanner. Also, I have a set of age-matched 20 subjects (controls) collected at location-2 with 3T Si

[Freesurfer] Cortical thickness using qdec (between scanners)

2016-09-29 Thread Martin Juneja
Hello FS experts, I have a data set of 20 subjects (patients) collected at location-1 with 3T Siemens scanner. Also, I have a set of age-matched 20 subjects (controls) collected at location-2 with 3T Siemens scanner. I am interested in comparing cortical thickness between controls and patients